Constructing a nomogram model for patients with cervical spondylotic myelopathy.

This study aims to construct a nomogram to predict the prognosis of patients with cervical spondylotic myelopathy (CSM). This study included 358 patients diagnosed with cervical spondylotic myelopathy. We collected serological indicators of patients at admission, including routine blood tests, biochemical tests, liver and kidney function, coagulation function and other laboratory tests.

Selective C(sp)-P Cross-Coupling of Alkenylsulfonium Salts with P(O)H Compounds: Divergent Synthesis of Alkenylphosphorus Compounds.

Herein, we report a both regioselective and stereoselective method for the formation of C(sp)-P bonds using alkenylsulfonium salts and >P(O)-H compounds. By employing a palladium catalyst or KCO, a variety of ()-alkenylphosphorus compounds and terminal alkenylphosphorus compounds were successfully synthesized with high selectivity. Notably, trisubstituted ()-alkenylphosphorus compounds were synthesized for the first time under metal-free conditions.

[The historical evolution of Chinese physiology textbooks].

This article systematically reviews the characteristics and trends of the writing, editing, publication and promotion of physiology textbooks in China from the late 19th century to the present, focusing on the introduction, development and innovation of Chinese physiology textbooks. The development of physiology textbooks in China is divided into four main stages: the introduction and initial development of physiology textbooks from the late 19th century to 1925; the localization and diversification of textbooks from 1926 to 1949, after the establishment of the Chinese Physiological Society; the exploratory phase of textbook construction after the founding of the People's Republic of China from 1949 to 1976; the formation and innovation of the textbook development process from 1977 to the present, following the restoration of the college entrance examination. For each phase, the article not only records the historical development of physiology textbooks, but also analyzes the evolution of their content, writing styles and the interaction with the social and political contexts.

Comparison of the Learning Curves of Ultrasound-Guided In-Plane Needle Placement Among Four Different Puncture Modes: A Randomized, Crossover, Simulation Study.

Background: The effects of different positional relationships between the probe, needle, and puncture model on in-plane puncture performance have not been fully evaluated. In this simulation study, we used a 4-period crossover design to compare the learning curves of ultrasound-guided in-plane needle placement among 4 different puncture modes by novices.

Methods: Forty residents were randomly assigned to receive training in one of 4 puncture modes according to the placement of the puncture model and the orientation of the probe to the operator: horizontal phantom-parallel probe (HP), horizontal phantom-vertical probe (HV), vertical phantom-parallel probe (VP), and vertical phantom-vertical probe (VV).

Preparation and characterization of Salecan β-glucan-based edible film loaded with lemon essential oil nanoemulsion: Effects on the preservation of chilled pork.

Chilled meat is highly prone to microbial spoilage, and edible films with antimicrobial properties offer a feasible solution. In this study, oil-in-water (O/W) nanoemulsions loaded with lemon essential oil (LEO) were developed. Nanoemulsification improved the antioxidant and antimicrobial activities of LEO.

Association between low-dose ionizing radiation and hypertension: a cohort study in China.

Objective: The association between high-dose ionizing radiation and the incidence of hypertension is well-established, whereas the impact of low-dose ionizing radiation (<20 mSv) on hypertension remains uncertain. The aim of this study is to assess the risk of hypertension among petroleum workers workers following long-term exposure to low-dose ionizing radiation (<20 mSv).

Methods: The study began in July 2013 and was followed up to December 2019.

Comprehensive Cross-Sectional Study of the Triglyceride Glucose Index, Organophosphate Pesticide Exposure, and Cardiovascular Diseases: A Machine Learning Integrated Approach.

Using NHANES data from 2003 to 2008, 2011 to 2012, and 2015 to 2020, we examined the relationship between urinary organophosphate pesticide (OPP) metabolites and the triglyceride glucose (TyG) index. The TyG index evaluates insulin resistance, a crucial factor in metabolic diseases. Linear regression analyzed urinary metabolites in relation to the TyG index and OPPs.

Foamy monocytes and atherogenesis in mice with combined hyperlipidemia and effects of antisense knockdown of apoCIII.

Hypertriglyceridemia (HTG), particularly in combined hyperlipidemia, increases risk for atherosclerotic cardiovascular disease, but the underlying mechanisms remain incompletely understood. We sought to determine contributions of circulating monocytes to atherosclerosis associated with HTG in combined hyperlipidemia, created by transgenic expression of human apoCIII in Ldlr mice (LdlrApoCIIItg) fed western high-fat diet (WD). Tissue culture with THP1 and primary human monocytes was used to examine effects of triglyceride (TG)-rich lipoproteins (TGRL) on monocytes.

Relative Aromaticity/Aliphaticity Steered Pore Structure in Polyamide-Derived Ultramicroporous Carbons for Efficient CH/CH Separation.

Carbon molecular sieves (CMS) with a tunable pore structure hold significant promise for efficient CH/CH separation. However, understanding the relationship between a precursor's carbon framework and the microstructure of carbonized products is still ambiguous and requires further investigation. Herein, a relative aliphaticity/aromaticity regulated strategy was proposed to tailor the carbon skeleton of the polyamide precursor, aiming to fine tune the CMS pore size between the kinetic diameter of CH (4.

A wearable enzyme sensor enabled by the floating-gate OECT with poly(benzimidazobenzophenanthroline) as the catalytic layer.

With the advantages of miniaturization, simple device structure, and fast response, the organic electrochemical transistor (OECT) has become an emerging platform for developing wearable enzyme sensors for real-time health monitoring. The floating gate (FG) OECT employs a distinct signal acquisition and amplification structure, mitigating the effects of non-specific physical adsorption during the sensing process and preventing contamination of the electrolyte solution by side reaction products. The current work reports a feasible wearable enzyme sensor using a poly(benzimidazobenzophenanthroline) (BBL)-Nafion-enzyme-Nafion stacking structure as the sensing layer of the FG OECT.

Musculoskeletal ultrasound-guided needle knife therapy in the treatment of refractory nonspecific low back pain: A single-blind, randomized controlled trial.

Background: This clinical study aimed to evaluate the Numerical Rating Scale (NRS), Oswestry disability index (ODI), and Japanese Orthopedic Association (JOA) scores at 2, 4, 6, and 12 weeks, and the thickness of the 4th lumbar multifidus under ultrasound at 6 and 12 weeks, using musculoskeletal ultrasound (MU)-guided needle-knife loosening therapy for treating refractory nonspecific low back pain (RNSLBP) compared to usual care, to demonstrate the clinical efficacy of needle knife therapy for RNSLBP. This study used a single-blind, randomized controlled design.

Methods: A total of 66 patients with RNSLBP who met the inclusion criteria were randomly divided into an observation group and a control group of 33 patients.

[Niche and Interspecific Association of Phytoplankton Dominant Species at Different Hydrological Periods in Xiaoche River, Guizhou Province].

To understand the niche and interspecific association of phytoplankton in different hydrological periods of the Xiaoche River in Guizhou Province, phytoplankton samples were collected in two different hydrological periods （dry period and wet period） from 2020 to 2022. The niche width （），niche overlap（），variance ratio method（VR），chisquare test（）, AC test, and Jaccard index （JI） were used to analyze the niche and interspecific association of phytoplankton dominant species. The results showed that a total of 7 phyla and 50 species of phytoplankton were identified in the Xiaoche River, with 4 phyla and 12 species being the dominant species.

Tolerogenic nanovaccines for the treatment of type I allergic diseases.

The high prevalence of type I allergic diseases such as allergic rhinitis, allergic asthma, food allergies, allergic conjunctivitis, and atopic dermatitis has emerged as a significant public health concern globally. Failure of immune tolerance to ordinarily harmless substances or stimulation, and subsequent induction of T helper 2 cells by antigen-presenting cells evokes the allergic immune response, which results in persistent inflammation, tissue damage, and organ function impairment. Current therapeutic approaches for allergic diseases include avoiding allergen exposure, corticosteroids, biologics, etc.

Age and diet affect self-resilience of intestinal microbiome in mice.

Background: Gut microbiota contributes to human health. Little is known about the self-resilience of the gut microbiota after dysbiosis. This study aimed to investigate the self-resilience of the gut microbiome at different ages and the effects of diet on its recovery capacity in adulthood.

Exploring the Role of Macrophages and Their Associated Structures in Rheumatoid Arthritis.

Background: Rheumatoid arthritis (RA) is a chronic, invasive autoimmune disease characterized by symmetrical polyarthritis involving synovial inflammation. Epidemiological studies indicate that the incidence of RA continues to rise, yet the pathogenesis of this disease remains not fully understood. A significant infiltration of macrophages is observed in the synovium of RA patients.

Trajectories and Influences of Depression in Adolescents: A Latent Profile Transition Analysis Study.

Depression has become increasingly prevalent among adolescents, posing significant challenges for mental health professionals. While most studies on depression adopt a cross-sectional perspective or a variable-centred approach, these methods often fail to illuminate the developmental trajectories of depression in individuals. We employed Latent Profile Transition Analysis (LPTA), a person-centred approach, to analyse longitudinal data from a large adolescent sample (N = 978; M = 16.

A HF-resistant perfluorinated porous polymer for the separation of electronic specialty gases.

A perfluorinated porous polymer, PFPP-1, featuring large (1068 m g) and ultrahigh fluorine content (35.6 at%), was synthesized to accomplish high HF resistance and selective adsorption of F-gases. Enhanced dipole interactions and optimal F-gas/N selectivity highlight PFPP-1's potential for efficient recovery of electronic specialty gases in sustainable electronics.

Usp7 contributes to the tail regeneration of planarians via Islet/Wnt1 axis.

Background: Regeneration plays a key role in energy recycling and homeostasis maintenance. Planarians, as ideal model animals for studying regeneration, stem cell proliferation, and apoptosis, have the strong regenerative abilities. Considerable evidence suggests that ubiquitin plays an important role in maintaining homeostasis and regulating regeneration, but the function of Ubiquitin specific proteases 7 (Usp7) on regeneration in planarians remains elusive.

Association between occupational exposure to gasoline and anemia: a retrospective cohort study in China.

Background: Anemia is a major global burden, and occupational gasoline exposure is a common occupational hazard factor. Although previous studies have shown that there is a potential relationship between occupational gasoline exposure and the increase of anemia prevalence, this relationship has not been fully explored. The current cohort study aimed to investigate the association between occupational exposure to gasoline and anemia, and the effect of gasoline concentration on hemoglobin (Hb) levels.

Evaluation and analysis of the transmission route of sigmoid sinus tinnitus by HRCT of the temporal bone: A retrospective analysis.

Objective: This study aims to analyze anatomical parameters of the transmission route of sigmoid sinus tinnitus (SST) to explore its mechanism and speculate on possible responsible anatomical abnormalities.

Methods: Clinical data were retrospectively collected from SST and sigmoid sinus wall dehiscence (SSWD) patients suggested by temporal bone high resolution computed tomography (HRCT), with and without tinnitus, at the First Affiliated Hospital of Chongqing Medical University from January 2015 to August 2022. Patients were divided into SSWD tinnitus ( = 61), and non-tinnitus ( = 60) groups based on HRCT features.

Nomogram model for decompressing craniectomy after mechanical thrombectomy in patients with acute ischemic stroke.

The most common treatment method for patients with acute ischemic stroke with large vessel occlusion is mechanical thrombectomy. However, complications such as cerebral edema and hemorrhage transformation after MT can affect patient prognoses, while decompression craniectomy considerably improves patient prognoses. The aim of this study was to identify clinical indicators, such as the neutrophil/high-density lipoprotein cholesterol ratio, to predict DC.

Comparative outcomes of ultrasound-guided radiofrequency ablation vs. microwave ablation for patients with T1N0M0 papillary thyroid carcinoma: a retrospective cohort study.

Objective: To compare the clinical outcomes between radiofrequency ablation (RFA) and microwave ablation (MWA) for the treatment of T1N0M0 papillary thyroid carcinoma (PTC) in a large cohort.

Materials And Methods: This retrospective study included 1111 patients with solitary T1N0M0 PTC treated with RFA (n = 894) or MWA (n = 215) by experienced physicians. A propensity score matching was used to compare disease progression, including lymph node metastases (LNM), recurrent tumors and persistent tumors, recurrence-free survival (RFS), volume reduction ratio (VRR), and complications between the RFA and MWA groups.

Multicenter study of thermal ablation versus partial thyroidectomy for paratracheal papillary thyroid microcarcinoma.

Objective: To compare the clinical outcomes of patients with unifocal paratracheal papillary thyroid microcarcinoma (PTMC) after thermal ablation (TA) vs. partial thyroidectomy (PT).

Materials And Methods: This retrospective multicenter study included 436 patients with unifocal, clinical N0 paratracheal PTMC who underwent TA (210 patients) or PT (236 patients) between June 2014 and December 2020.

Exposure to nano-polystyrene during pregnancy leads to Alzheimer's disease-related pathological changes in adult offspring.

Nanoplastics are common environmental pollutants. As of now, research has yet to explore how exposure to nanomaterials during gestation might influence the risk of developing Alzheimer's disease (AD) in offspring. Throughout the research, we assessed the AD pathology in adult offspring of mice prenatal 80 nm polystyrene nanoparticles (PS-NPs) exposure.