Publications by authors named "Jing Kun Liu"
Background: Resistant hypertension (RH) remains one of the major risk factors for cardiovascular disease. This study aims to investigate the association between the triglyceride-glucose (TyG) index and RH incidence in patients with hypertension and to construct a nomogram for predicting the occurrence of RH.
Methods And Results: A retrospective cohort study was conducted on 1635 patients initially diagnosed with hypertension at the Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University from August 2019 to August 2021.
Dipeptidyl peptidase III (DPP3), a zinc‑dependent metallopeptidase, is upregulated in a variety of malignancies. However, little is known about its roles in the pathogenesis of these malignancies. The present study was designed to investigate the roles of DPP3 in the pathogenesis and progression of oesophageal cancer (EC).
View Article and Find Full Text PDFArticle Synopsis
- Smoking has a significant impact on intestinal flora, especially in middle-aged and elderly males, as shown by a study collecting data from 188 patients.
- Analysis revealed that smokers had a different composition of gut bacteria compared to non-smokers, with specific genera such as Bifidobacterium being less abundant in smokers.
- Various correlations were found between certain bacteria and clinical indicators like blood glucose, uric acid, BMI, and liver enzyme levels, suggesting smoking influences not only gut health but also overall metabolic conditions.
Article Synopsis
- - The study investigated the differences in gut bacteria between diabetic patients and healthy individuals, finding that the gut flora in diabetics was significantly abnormal compared to the control group.
- - Certain bacteria genera, like Veillonella and specific Bacteroidales, were linked to blood glucose levels, with some excesses and deficiencies in specific types of bacteria detected among diabetics.
- - The research indicated that gut microbiota could serve as a valuable indicator for diagnosing diabetes, potentially being as crucial as fasting blood glucose levels in assessing the disease.
Asymptomatic hyperuricemia (AH) is an early stage of gout. Emerging evidence shows that the intestinal microbiota is related to gout. However, the relationship between AH and the intestinal microbiota is poorly understood.
View Article and Find Full Text PDFSirtuin 3 (SIRT3) modulates mitochondria-localized processes and is implicated in the metabolic reprogramming of cancer cells, especially fatty acid (FA) synthesis. However, the relationship between SIRT3 and aberrant lipid synthesis in cervical cancer remains unclear. Here, we investigated the clinical relevance of SIRT3 expression in cervical squamous cell carcinoma (CSCC), cervical intraepithelial neoplasia (CIN), and normal tissues.
View Article and Find Full Text PDF