Publications by authors named "Jing K"

Backgrounds: Considering the crucial role of military personnel's mental health in the armed forces, society, and the nation, the present study aims to describe the prevalence and influential factors of depression, anxiety, insomnia, and post-traumatic stress disorder (PTSD) among Chinese military personnel during the COVID-19 pandemic.

Methods: The present study conducted an epidemiological investigation of mental health among Chinese military personnel between October 25th and November 10th, 2022. Data was collected from military units in thirty provinces across the country.

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Background: Conventional systemic corticosteroid therapy for bullous pemphigoid (BP) has been challenged due to severe adverse events. Dupilumab has emerged as an alternative therapeutical option of BP patients.

Objectives: To evaluate the efficacy of dupilumab monotherapy and the combination with medium/low-dose corticosteroids for BP treatment.

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As the hybrid between cattle and yak, cattleyak is a typical male sterile mammal, and the underlying mechanism for its spermatogenic arrest is still unclear. In this study, the coding region of cattleyak TAF4B gene was cloned by RT-PCR and analysed by bioinformatics. To investigate the effects of TAF4B on cellular proliferation and differentiation, an expression vector was generated and introduced into undifferentiated spermatogonia (UDSPG) of cattleyak.

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Antibiotics are a widely distributed and effective antibacterial agents. Human medical treatment and livestock aquaculture are major sources of antibiotics in aquatic ecosystems, potentially damaging the biofilms that are the foundation of stream food webs. In this study, we conducted antibiotic biotransformation experiments using biofilms cultured in streams upstream and downstream of a wastewater treatment plant outlet to distinguish different fate processes of antibiotics in biofilms.

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In this paper, the adsorption of gatifloxacin (GAT) by three types of polystyrene nano-plastics (PSNPs), including 400 nm polystyrene (PS), amino-modified PS (PS-NH), and carboxyl-modified PS (PS-COOH) was studied and the adsorption mechanism were assessed. Experimental findings revealed that the equilibrium adsorption capacity of PSNPs to GAT followed the order PS-NH > PS-COOH > PS. The adsorption was regulated by both physical and chemical mechanisms, with intra-particle and external diffusion jointly controlling the adsorption rate.

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Mandibular defects requiring reconstructions may result from mandibular resections due to benign or malignant lesions. Prosthesis-based rehabilitation of such cases represents a challenge due to various anatomical and functional limitations. Here we present a novel design for the fabrication of a swing lock denture utilizing a simplified hinge and magnets for a patient who had undergone hemimandibulectomy.

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Article Synopsis
  • This paper discusses the design of a Class-AB power amplifier specifically for correcting nonlinearity in pressure-mode sensor applications, utilizing advanced circuit techniques to boost gain and maintain stability.
  • The amplifier employs a unique structure combining gain-boosting folded cascode, push-pull configuration, and adaptive output, resulting in a high-efficiency system that can handle resistive sensors ranging widely in resistance values.
  • Final simulations reveal the amplifier achieves over 140 dB gain and effectively reduces sensor nonlinearity to just 4% of its initial value, with minimal output voltage error despite varying environmental conditions.
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  • Myocardial arrhythmia is a serious complication of ischemia-reperfusion injury in diabetic patients, and the study investigates the protective role of irisin against this issue.
  • In an experiment with diabetic rats, irisin treatment showed a significant reduction in both the severity and occurrence of arrhythmias following I/R injury, affecting key proteins related to mitochondrial health, ER stress, and pyroptosis.
  • The results indicate that irisin may provide a therapeutic approach for managing arrhythmias in diabetic patients by improving mitochondrial function while reducing ER stress and pyroptosis, although further research is needed to validate its effectiveness in humans.
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Obesity is a major public health concern and burden on individuals and healthcare systems. Due to the challenges and limitations of lifestyle adjustments, it is advisable to consider pharmacological treatment for people affected by obesity. However, the side effects and limited efficacy of available drugs make the obesity drug market far from sufficient.

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Development of functional recovery therapies is critical to reduce the global impact of stroke as the leading cause of long-term disability. Our previous studies found that acute-phase protein orosomucoid (ORM) could provide an up to 6 h therapeutic time window to reduce infarct volume in acute ischemic stroke by improving endothelial function. However, its role in neurons and functional recovery post-stroke remains largely unknown.

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Wearable sensors for sweat trace metal monitoring have the challenges of effective sweat collection and the real-time recording of detection signals. The existing detection technologies are implemented by generating enough sweat through exercise, which makes detecting trace metals in sweat cumbersome. Generally, it takes around 20 min to obtain enough sweat, resulting in dallied and prolonged detection signals that cannot reflect the endogenous fluctuations of the body.

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Background: Anti-p200 pemphigoid is a rare autoimmune subepidermal blistering disease. Although the phenomenon of epitope spreading has been reported to be common in anti-p200 pemphigoid, the association between its clinical and immunoserological features has yet to be elucidated.

Objectives: Our aim was to compare the clinical and immunoserological characteristics of anti-p200 pemphigoid patients with and without epitope spreading.

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The three-dimensional (3D) organization of chromatin within the nucleus is crucial for gene regulation. However, the 3D architectural features that coordinate the activation of an entire chromosome remain largely unknown. We introduce an omics method, RNA-associated chromatin DNA-DNA interactions, that integrates RNA polymerase II (RNAPII)-mediated regulome with stochastic optical reconstruction microscopy to investigate the landscape of noncoding RNA -associated chromatin topology for gene equalization to achieve dosage compensation.

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Aim: A skin tear (ST) is a common skin injury that is often misdiagnosed or overlooked. This study examined the current state of nurses' ST knowledge and its influencing factors.

Design: A national cross-sectional survey combined with a quantitative analysis was used to provide evidence of poor ST knowledge among nurses and its influencing factors.

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Background: The manifestations of bullous pemphigoid (BP) and herpes simplex virus (HSV) infection are similar in oral mucosa, and the laboratory detection of HSV has some limitations, making it difficult to identify the HSV infection in oral lesions of BP. In addition, the treatments for BP and HSV infection have contradictory aspects. Thus, it is important to identify the HSV infection in BP patients in time.

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To explore the content and variation characteristics of water-soluble ions of atmospheric fine particles (PM) in a Beijing urban area and put forward the pollution prevention and control scheme, the water-soluble ions, gaseous precursors (SO, NO), and meteorological factors (temperature, RH) of PM in 2022 were analyzed and determined. The results showed that the water-soluble ions with the highest proportion in PM in the Beijing City urban area were NO, NH, and SO, accounting for 52.7% of PM.

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Electrochromic materials allow for optical modulation and have attracted much attention due to their bright future in applications such as smart windows and energy-saving displays. Two-dimensional (2D) molybdenum oxide nanoflakes with combined advantages of high active specific surface area and natural layered structure should be highly potential candidates for electrochromic devices. However, the efficient top-down preparation of 2D MoO nanoflakes is still a huge challenge and the sluggish ionic kinetics hinder its electrochromic performance.

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The correlation between IgE anti-BP180 NC16A autoantibody and disease activity of bullous pemphigoid (BP) remains disputable. To determine the levels of IgE anti-BP180 NC16A autoantibody and its clinical significance in untreated BP patients. IgG and IgE anti-BP180 NC16A autoantibody in serum and blister fluid samples of 34 untreated BP patients was detected by enzyme-linked immunosorbent assay (ELISA), and correlation with clinical and pathological features of BP were statistically analysed.

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Article Synopsis
  • Anti-LC1 antibodies serve as a marker for type 2 autoimmune hepatitis but are not specific to it, as they appear in various liver disorders.
  • A study of 157 anti-LC1 positive patients examined the link between their liver diagnoses and the risk of decompensated cirrhosis or liver failure (DC/LF).
  • Results indicated that viral hepatitis significantly increased the risk of DC/LF in these patients, highlighting the need to consider viral infections over autoimmune liver diseases in risk assessments.
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The presence of autoantibodies is closely associated with the occurrence and development of cancer. Autoantibodies can be used as biomarkers for early breast cancer diagnosis. However, the relationship between autoantibodies and the prognosis of breast cancer patients remains elusive.

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Goniogryllus bistriatus Wu & Wang, 1992 was described at the end of the last century, based on the female holotype, and there have been no further studies or reports related to this species since then. Callogryllus yunnanus Wu & Zheng, 1992 also has a similar situation. Although the holotype is a male, its external genitalia have been lost.

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Larvae of Pseudopyrochroa girardi were collected beneath bark and in coarse, decaying woody debris of dead logs in Yaan City, Sichuan Province, China. The species association was confirmed by rearing both males and females to the adult stage. The last instar larva is described and illustrated, along with the first description of the adult female.

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To clarify the characteristics and source apportionment of the VOCs initial mixing ratio in Beijing in summer, continuous monitoring of VOCs was conducted in the Beijing urban area from May to August 2022, and the initial mixing ratio was calculated using the photochemical ratio method. The results showed that:① during the study period, initial (TVOCs) in the Beijing urban area were (30.0 ±11.

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