Publications by authors named "Jing Jian Dong"

Article Synopsis
  • Prenatal exposure to heavy metals, especially mercury (Hg), may disrupt neurodevelopment and affect hormone levels in children, highlighting a risk in areas near electronic waste recycling in China.* -
  • The study analyzed human milk and serum steroid hormones in children at age four, finding a significant association between higher Hg levels and increased dehydroepiandrosterone (DHEA) concentrations.* -
  • Results suggest that while Hg may influence hormone levels, the effect is complex due to exposure to multiple metals, emphasizing the need for regulatory measures to mitigate heavy metal exposure.*
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This study is the first to assess postnatal exposure to heavy metals using breast milk in an electronic waste (e-waste) recycling area. From January to April 2021, 102 and 97 breastfeeding women were recruited from an e-waste recycling area and a control area, respectively. Four weeks after delivery, medical staff collected 20 mL of breast milk from each participant.

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Article Synopsis
  • This observational study revisits the impact of dioxin exposure on the synthesis of steroid hormones in infants by analyzing data from 42 mother-infant pairs previously studied in 2015.
  • Researchers assessed serum samples for four steroid hormones—progesterone, testosterone, androstenedione (A-dione), and dehydroepiandrosterone (DHEA)—while also measuring dioxin levels in breast milk.
  • The study found a significant negative correlation between dioxins and DHEA and A-dione, but not with progesterone and testosterone, highlighting the need for ongoing monitoring of dioxin effects on hormone levels in children since earlier studies indicated different relationships.
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In the past two decades, numerous studies on dioxin concentrations in breast milk have been conducted in China. However, information concerning dioxin concentrations in breast milk from women living in e-waste recycling sites remains limited. Thus, this study aimed to evaluate health risk owing dioxin intake in e-waste recycling areas in China.

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Perinatal exposure to dioxins affects steroid hormone synthesis. The purpose of the present study was to evaluate the associations between perinatal exposure to dioxins and serum steroid hormone levels in preschool-aged children from an e-waste recycling region in China. In the present study, we enrolled 50 pairs of mothers and infants from the Taizhou, Luqiao region in 2015.

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As observed among residents in electronic waste (e-waste) recycling areas, dioxins can disrupt the homeostasis of endocrine hormones and the balance of thyroid hormones. Few studies, however, have examined whether e-waste recycling activities influence steroid hormone equilibrium in the general adult male population. This study evaluated the association between steroid hormones and the physical burdens of dioxins in the general adult male population residing in an e-waste region.

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The purpose of this study was to investigate the longitudinal effects of perinatal exposure to dioxin on physical growth in a 3-year follow-up study. In 2015, 27 mother-infant pairs living in an electronic waste (e-waste) dismantling region and 35 pairs living in a control region were enrolled in the present study. Breast milk samples were collected at 4 weeks after birth.

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Background: Owing to the multifactorial nature of the pathogenesis of diabetic peripheral neuropathy (DPN), conventional drug therapies have not been effective. The application of stem cells transplantation may be useful for the treatment of DPN. This study was designed to assess the safety and therapeutic effects of autologous bone marrow mononuclear cells (BMMNCs) transplantation on the treatment of refractory DPN.

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