Exploring hepatic fibrosis screening via deep learning analysis of tongue images.

Background: Tongue inspection, an essential diagnostic method in Traditional Chinese Medicine (TCM), has the potential for early-stage disease screening. This study aimed to evaluate the effectiveness of deep learning-based analysis of tongue images for hepatic fibrosis screening.

Methods: A total of 1083 tongue images were collected from 741 patients and divided into training, validation, and test sets.

Contrast-enhanced transcranial Doppler for the detection of right-to-left shunt: A new provocation method with a syringe-modified Valsalva maneuver.

Background: Contrast-enhanced transcranial Doppler (cTCD) study has been established as one of the most common investigations for detecting right-to-left shunt (RLS). Although the conventional Valsalva maneuver (c-VM) has been used to increase the sensitivity of cTCD for RLS, efforts are still needed to improve the detection rate further. We proposed a new provocation method with a syringe-modified Valsalva maneuver (sm-VM) during cTCD and compared the efficacy of this strategy with cTCD measured at resting and with the provocation of c-VM.

Physicochemical and Structural Characterization of Alkali-Treated Biopolymer Sphingan WL Gum from Marine sp. WG.

Sphingan WL gum (WL), a kind of exopolysaccharide, is produced by sp. WG, which was screened from sea mud samples of Jiaozhou Bay by our group. The solubility of WL was investigated in this work.

Observing the quantum topology of light.

Topological photonics provides a powerful platform to explore topological physics beyond traditional electronic materials and shows promising applications in light transport and lasers. Classical degrees of freedom are routinely used to construct topological light modes in real or synthetic dimensions. Beyond the classical topology, the inherent quantum nature of light provides a wealth of fundamentally distinct topological states.

Digital quantum simulation of Floquet symmetry-protected topological phases.

Quantum many-body systems away from equilibrium host a rich variety of exotic phenomena that are forbidden by equilibrium thermodynamics. A prominent example is that of discrete time crystals, in which time-translational symmetry is spontaneously broken in periodically driven systems. Pioneering experiments have observed signatures of time crystalline phases with trapped ions, solid-state spin systems, ultracold atoms and superconducting qubits.

Citric acid crosslinked sphingan WL gum hydrogel films supported ciprofloxacin for potential wound dressing application.

Sphingan WL gum (WL), a kind of exopolysaccharides, is produced by Sphingomonas sp. WG. In this study, citric acid (CA) crosslinked WL hydrogel films were firstly developed for potential wound dressing application.

LncRNA Promotes Proliferation, Migration, and Invasion of Glioma Cells Through Regulating the / Axis.

officially retracts the paper entitled, "LncRNA Promotes Proliferation, Migration, and Invasion of Glioma Cells Through Regulating the Axis," by Fangen Kong, Yang Yan, Jinfeng Deng, Yaoli Zhu, Yingqin Li, Huiqing Li, and Yiping Wang (Cancer Biother Radiopharm. E-pub ahead of print 23 Jul 2020; doi: 10.1089/cbr.

Generation and Application of Mouse Monoclonal Antibody Against Human Cytomegalovirus UL23.

Human cytomegalovirus (HCMV) is a paradigm for pathogen-mediated immune evasion. The immune response to HCMV has been intensively studied for many years and still remains the focus of attention for numerous research groups. is an early gene of HCMV, belonging to the US22 gene family, encoding protein UL23.

Circ_016719 plays a critical role in neuron cell apoptosis induced by I/R via targeting miR-29c/Map2k6.

Background: Stroke is a leading cause of mortality worldwide. Rac-MAPK kinase 6 (Map2k6) plays important roles in cell proliferation and apoptosis. However, the role played by Map2k6 in stroke injury and the underlying mechanism of action remain unknown.

Preparation and identification of polyclonal antibody against human cytomegalovirus encoding protein UL23.

Human cytomegalovirus (HCMV), a member of the human herpesvirus family, is a common opportunistic virus causing severe ailments and deaths in people with immature or compromised immune systems. UL23 is a virion protein found in the tegument and is expressed in the cytoplasm in HCMV infected cells. However, UL23 is dispensable for viral replication in cultured cells and little is currently known about its function.

[Association between angiotensin-converting enzyme gene polymorphism and Alzheimer's disease].

Objective: To determine the association between the polymorphism of angiotensin converting enzyme (ACE) gene and Alzheimer's disease (AD).

Methods: This case-control study involved 201 AD patients and 257 healthy subjects matched for age and gender as the control group. Polymerase chain reaction amplification and matrix-assisted laser desorption/ ionization time of flight mass spectrometry were used to examine the rs4291, rs4309, and rs4343 of ACE gene, and the difference in genotypes, allelotype frequencies and haplotype frequencies were analyzed between the two groups.

Effect of the +781C/T polymorphism in the interleukin-8 gene on atherosclerotic cerebral infarction, and its interaction with smoking and drinking.

Objective: The aims of this study were to investigate the association between the +781C/T polymorphism of interleukin-8 (IL-8) and atherosclerotic cerebral infarction and the interaction between the +781C/T polymorphism and smoking or drinking in cerebral infarction in the Han Chinese population.

Methods: We investigated the +781C/T polymorphism of IL-8 in 308 consecutive Han Chinese patients who were diagnosed with atherosclerotic cerebral infarction and in 294 age- and gender-matched healthy control subjects. The patients were classified using the Oxfordshire Community Stroke Project (OCSP) classification.

Nanoporous titanium borophosphates with rigid gainesite-type framework structure.

Nanoporous titanium borophosphates have been synthesized which exhibit a rigid gainesite-type framework of polyhedra. The open-framework character is supported by the reversibility of de- and rehydration processes.

[Effect of willed movement therapy on GFAP and SYP expression in rats with cerebral ischemia-reperfusion].

Objective: To determine the effect of willed movement on the expression of glial fibrillary acidic protein (GFAP) and synaptophysin (SYP) in adult rats with cerebral ischemia-reperfusion, and explore the mechanism of willed movement in promoting nerve repair and regeneration.

Methods: Adult rat models of cerebral ischemia-reperfusion injury were established by middle cerebral artery occlusion (MCAO) for 2 h followed by a 24-h reperfusion. The models were then divided randomly into 3 groups, namely the model group, environmental modification (EM) group, and willed movement (WM) group.

[Effect of willed movement therapy on the expression of neurotrophin 3 and growth-associated protein 43 in rats with cerebral ischemia reperfusion].

Objective: To observe the effect of willed movement therapy on the expression of neurotrophin 3 (NT-3) and growth associated protein 43 (GAP-43) in rats with cerebral ischemia-reperfusion (IR) and investigate the neuroprotective mechanism of willed movement therapy in nerve regeneration and repair.

Methods: Cerebral IR model was established by middle cerebral artery occlusion (MCAO) in SD rats. The rats were randomly divided into MCAO group, environment modification group (EM group) and willed movement therapy group (WM group).