Modulating the structure of Cu in CuX/CNTs hollow tetrakaidecahedron to enhance high-efficiency HO production.

Regulation of active sites of electrocatalysts is critical in adjusting electronic structure and catalytic selectivity towards oxygen reduction reaction (ORR) to hydrogen peroxide (HO). Herein, the CuX/CNTs (X = Se, SSe, S) hollow tetrakaidecahedron catalysts were synthesized to facilitate the electrocatalytic reduction of O to HO. The introduction of S resulted in a shift from four-electron pathway on CuSe/CNTs to two-electron process on CuS/CNTs, ultimately leading to an enhancement in HO productivity.

Kirigami Design Smart Contact Lens for Highly Sensitive Eyelid Pressure Measurement.

Eyelid pressure is a crucial biomechanical parameter for ocular health and refractive status, yet measuring it poses challenges related to flexibility, sensitivity, and regional specificity. This study introduces a novel smart contact lens that incorporates kirigami designs and an iontronic capacitive sensing array to enhance flexibility and conformability. The unique structural composition of this device allows for precise and simultaneous monitoring of eyelid pressure in multiple regions with a high sensitivity and seamlessly fit across corneal curvatures.

Green interface optimization strategy based on allium mongolicum regel extract for enhanced alkaline Al-air battery performance.

Aqueous aluminum (Al)-air batteries (AABs) are gaining significant attention due to their excellent theoretical performance. However, the self-corrosion of the aluminum anode reduces anodic efficiency and battery capacity, limiting the broad commercial application of AABs. Herein, we propose the utilizing Allium Mongolicum Regel (AMR) extract as a green electrolyte additive to optimize the Al anode/electrolyte interface in alkaline AABs.

Scale-up construction of stable multifunctional hydrogel interfaces for large-scale purification of complex oil-water emulsions and oil recovery.

Inspired by the multi-level structure of grass clumps in nature, a novel filter with plexiform-structured hydrogel interface was constructed using sepiolite-derived silica nanofiber (SiNF) as the supporter and crosslinked polyvinyl alcohol (cl-PVA) hydrogel as the coating. Experimental test, DFT and MD calculations have confirmed that the addition of SiNF can not only enhance oil-water separation efficiency, but also improve the stability of hydrogel coating. The hydrogel interface with excellent stability and superhydrophilic/underwater superoleophobicity can be manufactured on a large copper mesh (1 m × 1.

Clinical effect of botulinum toxin type A combined with autologous fat grafting in patients with nasolabial fold depression.

Background: Nasolabial fold (NLF) depression can affect the facial appearance of patients to some extent and increase their psychological burdens. In recent years, autologous fat grafting (AFG) combined with botulinum toxin A (BTX-A) injection (AFG + BTX-A injection) has been gradually applied in the treatment of patients with NLF depression. Although studies have been conducted on the efficacy and safety of AFG + BTX-A injection in treating NLF depression, the experimental design, observational indicators, and sample enrollment criteria vary remarkably, making it difficult to draw convincing and consistent conclusions.

A dual-labeling molecule for efficient drug discovery of mitochondrial-lysosomal interactions.

The close association between organelle interactions, such as mitochondrial-lysosomal interactions, and various diseases, including tumors, remains a challenge for drug discovering and identification. Conventional evaluation methods are often complex and multistep labeling procedures often generate false positives, such as cell damage. To overcome these limitations, we employed a single dual-color reporting molecule called Coupa, which labels mitochondria and lysosomes as blue and red, respectively.

In Vivo Corneal Biomechanical Response to Three Different Laser Corneal Refractive Surgeries.

Purpose: To compare the effects of three common refractive surgeries on corneal biomechanics.

Methods: Two hundred seven patients who had refractive surgery were included in this study, of whom 65 received transepithelial photorefractive keratectomy (tPRK), 73 received femtosecond laser-assisted laser in situ keratomileusis (FSLASIK), and 69 received small incision lenticule extraction (SMILE). Each patient had biomechanical measurements using the Corvis ST (Oculus Optikgeräte GmbH) preoperatively and at 3 and 6 months postoperatively.

Altering optical zone diameter, reverse curve width, and compression factor: impacts on visual performance and axial elongation in orthokeratology.

Purpose: To investigate the effects of modifications in back optical zone diameter (BOZD), reverse curve width (RCW), and compression factor (CF) on refractive error changes and axial elongation in myopic children undergoing orthokeratology (ortho-k) over a 12-month period.

Method: In this retrospective study, data from 126 myopic children undergoing ortho-k fitting were analyzed. Subjects were categorized into four distinct groups based on lens design parameters: Group A (BOZD 6.

Evaluation of changes in corneal biomechanics after orthokeratology using Corvis ST.

Purpose: To investigate the alterations in corneal biomechanical metrics induced by orthokeratology (ortho-k) using Corvis ST and to determine the factors influencing these changes.

Method: A prospective observational study was conducted to analyze various Corvis ST parameters in 32 children with low to moderate myopia who successfully underwent ortho-k lens fitting. Corneal biomechanical measurements via Corvis ST were acquired at six distinct time points: baseline (pre) and 2 h (pos2h), 6 h (pos6h), and 10 h (pos10h) following the removal of the first overnight wear ortho-k, one week (pos1w) and one month (pos1m) subsequent to the initiation of ortho-k.

Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in hyperlipidemic rats by inhibiting inflammation, oxidative stress and NF-κB.

The present study was conducted to determine the protective effect of Dexmedetomidine (DEX) in myocardial ischemia-reperfusion injury in hyperlipidemic rats. Towards this, the effect of DEX was first evaluated on the infarct size and the histopathology of cardiac tissues using TTC and H and E staining, and it was found that DEX significantly improved the infarct size and architecture of the myocardial tissues following the I/R injury. DEX also showed significant improvement in various examined hemodynamic parameters (e.

Regulating the Electronic Structure of Ni Sites in Ni(OH) by Ce Doping and Cu(OH) Coupling to Boost 5-Hydroxymethylfurfural Oxidation Performance.

Biomass is a sustainable and renewable resource that can be converted into valuable chemicals, reducing the demand for fossil energy. 5-Hydroxymethylfurfural (HMF), as an important biomass platform molecule, can be converted to high-value-added 2,5-furandicarboxylic acid (FDCA) a green and renewable electrocatalytic oxidation route under mild reaction conditions, but efficient electrocatalysts are still lacking. Herein, we rationally fabricate a novel self-supported electrocatalyst of core-shell-structured copper hydroxide nanowires@cerium-doped nickel hydroxide nanosheets composite nanowires on a copper mesh (CuH_NWs@Ce:NiH_NSs/Cu) for electrocatalytically oxidizing HMF to FDCA.

Trehalose promotes functional recovery of keratinocytes under oxidative stress and wound healing via ATG5/ATG7.

Wounds are in a stressed state, which precludes healing. Trehalose is a stress metabolite that protects cells under stress. Here, we explored whether trehalose reduces stress-induced wound tissue damage.

Development and Validation of a Nomogram for Predicting Second Surgery in Patients with Concomitant Esotropia.

Introduction: This study developed and validated a nomogram for predicting the risk of second surgery in patients with concomitant esotropia (CE) based on a cohort in Beijing.

Methods: In this retrospective cohort study, the inpatient and outpatient medical records of 419 patients with CE who underwent surgery at the Peking University First Hospital between January 1, 2005 and December 31, 2009 were collected. A total of 357 CE cases were included.

Circulating levels of Elabela in pregnant women with missed abortion.

This study aimed to detect Elabela concentrations in the serum of Missed abortion (MA) and compare them with the healthy pregnancies.This retrospective case-control study was performed in the second affiliated hospital, Xi'an Jiaotong University March 2019 to September 2019. A total of 108 healthy (35 early, 36 middle and 37 late) pregnant women and 25 (early gestational stage) MA patients were involved.

Synthesis of Nitrogen-Doped KMn O with Oxygen Vacancy for Stable Zinc-Ion Batteries.

The development of MnO as a cathode for aqueous zinc-ion batteries (AZIBs) is severely limited by the low intrinsic electrical conductivity and unstable crystal structure. Herein, a multifunctional modification strategy is proposed to construct N-doped KMn O with abundant oxygen vacancy and large specific surface area (named as N-KMO) through a facile one-step hydrothermal approach. The synergetic effects of N-doping, oxygen vacancy, and porous structure in N-KMO can effectively suppress the dissolution of manganese ions, and promote ion diffusion and electron conduction.

Inflammation-Related Gene Signature: An Individualized Risk Prediction Model for Kidney Renal Clear Cell Carcinoma.

Background: There is much evidence that confirms the inextricable link between inflammation and malignancy. Inflammation-related regulators were involved in the progression of kidney renal clear cell carcinoma (KIRC). However, the predictive role of single gene biomarkers is inadequate, and more accurate prognostic models are necessary.

The Biomechanical Response of the Cornea in Orthokeratology.

Orthokeratology has been widely used to control myopia, but the mechanism is still unknown. To further investigate the underlying mechanism of corneal reshaping using orthokeratology lenses the finite element method, numerical models with different corneal curvatures, corneal thicknesses, and myopia reduction degrees had been developed and validated to simulate the corneal response and quantify the changes in maximum stress in the central and peripheral corneal areas during orthokeratology. The influence of the factors on corneal response had been analyzed by using median quantile regression.

Engineering Active Sites of Gold-Cuprous Oxide Catalysts for Electrocatalytic Oxygen Reduction Reaction.

Understanding how the catalyst morphology influences surface sites is crucial for designing active and stable catalysts and electrocatalysts. We here report a new approach to this understanding by decorating gold (Au) nanoparticles on the surface of cuprous oxides (CuO) with three different shape morphologies (spheres, cubes, and petals). The Au-CuO particles are dispersed onto carbon nanotube (CNT) matrix with high surface area, stability, and conductivity for oxygen reduction reaction.

Active Sites and Interfacial Reducibility of CuO/CeO Catalysts Induced by Reducing Media and O/H Activation.

The development of a highly efficient and stable catalyst for preferential oxidation of CO for the commercialization of proton-exchange membrane fuel cells has been a result of continuous effort. The main challenge is the simultaneous control of abundant active sites and interfacial reducibility over the catalyst CuO/CeO. Here, we report a strategy to modulate porosity, active sites, and O-vacancy sites (O) by reducing media and O/H activation.

Orthokeratology lens-related keratitis: case report and analytical review.

keratitis (AK) is a rare but severe ocular infection with a significant risk of vision loss. Contact lens use is the main risk factor for AK. The orthokeratology (OK) lens, a specially designed contact lens, has been used worldwide as an effective method of myopia control.

Prenatal diagnosis of pulmonary artery sling associated with tracheal agenesis: A case report.

Pulmonary artery sling (PAS) and tracheal agenesis (TA) are rare diseases, and most cases of PAS are associated with tracheal bronchial malformations. However, PAS associated with TA is yet to be reported. We report a case of PAS with TA diagnosed prenatally.

Probing Heteroatomic Dopant-Activity Synergy over CoO/Doped Carbon Nanotube Electrocatalysts for Oxygen Reduction Reaction.

Understanding and predicting how heteroatomic dopants of carbon nanotubes (CNTs)-based catalysts alter their catalytic performance at nanoscale is essential to design superior electrocatalysts for oxygen reduction reaction (ORR). This report describes findings of an investigation of the heteroatomic dopant-activity relationship for CoO/doped CNTs catalysts with different heteroatoms including N, O, and P atoms in ORR. By using an array of techniques to probe the structure and elementary valence of the catalysts, the incorporation of the CoO nanoparticles can introduce defects into the doped CNTs, especially the N-CNTs, which should contribute to the generation of active sites.

Investigation of the underling mechanism of ketamine for antidepressant effects in treatment-refractory affective disorders via molecular profile analysis.

Ketamine elicits a rapid antidepressant effect in treatment-refractory affective disorders. The aim of the present study was to elucidate the underlying mechanism of this effect and to identify potential targets of ketamine for antidepressant effects. GSE73798 and GSE73799 datasets were downloaded from the Gene Expression Omnibus database.