Publications by authors named "Jinfang Cao"

The aim of this study is to prepare hybrid polymer-ceramic dental materials for chairside computer-aided design/computer-aided manufacturing (CAD/CAM) applications. The hybrid polymer-ceramic materials were fabricated via infiltrating polymerizable monomer mixtures into sintered hydroxyapatite/bioactive glass (HA/BAG) ceramic blocks and thermo-curing. The microstructure was observed by scanning electron microscopy and an energy-dispersive spectrometer.

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Aim: A meta-analysis was conducted in order to investigate the potential association of vitamin D receptor (VDR) gene polymorphisms with susceptibility to aggressive and chronic periodontal disease.

Material And Methods: A database search yielded a total of 15 studies involving 1338 cases and 1302 controls. Four polymorphisms were included in the meta-analysis: VDR TaqI (rs731236), VDR BsmI (rs1544410), VDR FokI (rs2228570), and VDR ApaI (rs7975232).

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Article Synopsis
  • - The study aimed to explore how the expression of epidermal growth factor receptor (EGFR) changes in human periodontal ligament cells (hPDLC) during their mineralization process in a lab setting.
  • - Researchers used methods like immunolocalization and RT-PCR to track changes in EGFR expression over time, finding that the presence of EGFR decreased significantly by the fourth week of the mineralization process.
  • - The findings suggest that EGFR plays a negative regulatory role in the mineralization of hPDLC, indicating that as mineralization progresses, the expression of EGFR declines.
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Objective: To investigate the biocompatibility of chitosan-carboxymethylchitosan as membrane for periodontal guided tissue regeneration (GTR).

Methods: Chitosan-carboxymethylchitosan blending membrane was prepared by freeze-drying and tests including cytotoxicity test, inserting the membrane into the rabbits, muscles, were employed to investigate its biocompatibility.

Results: Chitosan-carboxymethylchitosan blending membrane showed no toxicity.

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