A novel immunogenic cell death signature for the prediction of prognosis and therapies in glioma.

Glioma is a primary cranial malignancy with high recurrence rate, poor prognosis and high mortality. However, the roles of immunogenic cell death (ICD) in glioma remain unclear. Twenty ICD genes were analyzed to be differentially expressed between glioma tissues and non-tumor tissues in 371 glioma patients from The Cancer Genome Atlas (TCGA).

Analysis and Design of Robust H∞ Fault Estimation Observer With Finite-Frequency Specifications for Discrete-Time Fuzzy Systems.

This paper addresses the problem of fault estimation observer design with finite-frequency specifications for discrete-time Takagi-Sugeno (T-S) fuzzy systems. First, for such T-S fuzzy models, an H∞ fault estimation observer with pole-placement constraint is proposed to achieve fault estimation. Based on the generalized Kalman-Yakubovich-Popov lemma, the given finite-frequency observer possesses less conservatism compared with the design of the entire-frequency domain.

Value of T2-mapping and DWI in the diagnosis of early knee cartilage injury.

Objective: To study the value of T2-mapping and diffusion weighted imaging (DWI) in the diagnosis of early injury of knee cartilage.

Methods: Seventy-two subjects, including healthy group (n=30) and early cartilage injury group (n=42), were tested on MR scans with T2-mapping and DWI. T2 and apparent diffusion coefficient (ADC) values of cartilage were measured after being processed at the workstation, and the differences were statistically analyzed between the two groups.

MR imaging of the cisternal segment of the posterior group of cranial nerves: neurovascular relationships and abnormal changes.

Objective: To evaluate the detailed anatomic features, neurovascular relationships of the cisternal segment of the posterior group of cranial nerves (PGCN: IX, X, XI, XII); to evaluate the utility of magnetic resonance (MR) in demonstrating the PGCN with disorders caused by abnormal compression related to artery or tumor.

Methods: A total of 59 volunteers, 12 patients with abnormal symptom in the PGCN underwent three-dimensional (3D) Fourier transformation constructive interference in steady-state (CISS) MR imaging, and 22 of these volunteers and 12 patients also underwent MR angiography in which a time-of-flight (TOF) sequence was used to further distinguish the PGCN from the adjacent blood vessels. Anatomical features, neurovascular relationships of the PGCN in 59 volunteers and abnormal changes in 12 patients caused by neurovascular compression or tumor were observed from multi-planar reconstruction (MPR) images, cryomicrotome section and 3D-CISS MR imaging of cranial cadaver were used to testify the PGCN displayed in 59 volunteers.