Publications by authors named "Jindi Lei"
Article Synopsis
- The study aims to establish how anxiety and depression affect the progression and treatment outcomes of vitiligo, aiming to improve psychological care for patients.
- Using a Mendelian randomization analysis and various statistical tests, researchers found that depression notably increases the risk of developing vitiligo and that different levels of anxiety and depression correlate with varying clinical characteristics in patients.
- The results indicate that moderate to severe anxiety-depression negatively impacts treatment effectiveness, establishing a U-shaped relationship where the most significant influence occurs at specific anxiety-depression scores.
Vitiligo is an acquired autoimmune skin disease characterized by patchy depigmentation of the skin, often accompanied by white hair. The aetiology of vitiligo is complex and difficult to cure, and its disfiguring appearance significantly impacts patients' mental and physical health. Psychological stress is a major factor in inducing and exacerbating vitiligo, as well as affecting its treatment efficacy, though the specific mechanisms remain unclear.
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