Publications by authors named "Jinchen Long"
Anthropogenic evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are currently built from six different nucleotides. Thus, six-letter AEGIS-LIVE delivers AegisBodies with greater stability in biological mixtures, more folds, and enhanced binding and catalytic power.
View Article and Find Full Text PDFAnthropogenic evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are currently built from six different nucleotides. Thus, six-letter AEGIS-LIVE delivers AegisBodies with greater stability in biological mixtures, more folds, and enhanced binding and catalytic power.
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- Three new compounds, named moralbaflavones A-C, were discovered from the root barks of a specific plant species.
- The structures and configurations of these compounds were analyzed using techniques like HRMS, NMR, and ECD.
- Among the compounds tested for neuroprotective properties, moralbaflavone C showed significant effectiveness, outperforming the established neuroprotective agent edaravone in the study.
A pair of undescribed dihydrobenzofuran neolignan enantiomers, (+/-)-phybrenan A (/), two new benzofuran neolignans, phybrenan B and C ( and ), along with four known neolignans (-) were obtained from the plants of P. T. Li.
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