Publications by authors named "Jinbaek Lee"
Article Synopsis
- Japanese quail are important for providing protein but their sexual dimorphism is not well understood compared to other species.
- Researchers analyzed RNA sequencing data from quails and chickens to identify sex-biased genes in different tissues and stages of development.
- Results showed that quails and chickens have similar gene expression patterns related to sex determination, but there are unique challenges due to the lack of global dosage compensation in quails that could affect breeding and transgenic efforts.
Introduction: For reference genomes and gene annotations are key materials that can determine the limits of the molecular biology research of a species; however, systematic research on their quality assessment remains insufficient.
Methods: We collected reference assemblies, gene annotations, and 3,420 RNA-sequencing (RNA-seq) data from 114 species and selected effective indicators to simultaneously evaluate the reference genome quality of various species, including statistics that can be obtained empirically during the mapping process of short reads. Furthermore, we newly presented and applied transcript diversity and quantification success rates that can relatively evaluate the quality of gene annotations of various species.