Publications by authors named "Jina Ha"

The gut microbiome is a dynamic ecosystem crucial for maintaining its host's health by regulating various immune and metabolic functions. Since diet plays a fundamental role in shaping the gut microbiome, understanding the relationship between food consumption and microbiome structure is essential. Although medicinal plants are widely recognized for their broad health benefits, their specific impact on the gut microbiome remains unclear.

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Article Synopsis
  • - The study focuses on enterohemorrhagic Escherichia coli (EHEC) in South Korea, which is linked to serious outbreaks and infections, with around 2000 reported cases since it became notifiable in 2000.
  • - Researchers conducted genetic analyses using real-time PCR and whole-genome sequencing to identify virulence and antimicrobial resistance genes in hybrid strains (STEC/aEPEC) found in livestock and environmental samples.
  • - Findings revealed that these hybrid strains possess key virulence factors, demonstrating cytotoxic effects and invasive abilities towards human cells, which may be influenced by specific genetic types, highlighting a need for further investigation into their pathogenic potential.
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Hybrid strains acquires genetic characteristics from multiple pathotypes and is speculated to be more virulent; however, understanding their pathogenicity is elusive. Here, we performed genome-based characterization of the hybrid of enteropathogenic (EPEC) and enterotoxigenic (ETEC), the strains that cause diarrhea and mortality in children. The virulence genes in the strains isolated from different sources in the South Korea were identified, and their phylogenetic positions were analyzed.

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Outbreaks of food poisoning due to the consumption of norovirus-contaminated shellfish continue to occur. Male-specific (F+) coliphage has been suggested as an indicator of viral species due to the association with animal and human wastes. Here, we compared two methods, the double agar overlay and the quantitative real-time PCR (RT-PCR)-based method, for evaluating the applicability of F+ coliphage-based detection technique in microbial contamination tracking of shellfish samples.

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