Maternal multivitamin supplementation mitigates the risk of fetal congenital heart disease associated with high indoor total volatile organic compounds exposure in east china: a case-control study.

Background: Congenital heart disease (CHD) is a common birth defect. Our previous studies suggest that indoor air pollution, especially total volatile organic compounds (TVOCs), may increase fetal CHD risk, whereas vitamin and folic acid (FA) supplements in early pregnancy might offer protection against CHD. However, limited research has explored whether FA or multivitamin supplementation can mitigate the effects of TVOCs exposure on CHD.

Environmental DNA/RNA metabarcoding for noninvasive and comprehensive monitoring and assessment of marine fishes.

Marine fisheries resources are under increasing threat, necessitating the development of new effective monitoring and management strategies. Environmental DNA (eDNA) and RNA (eRNA) metabarcoding has emerged as a non-invasive and sensitive alternative method for monitoring fish biodiversity and fisheries resources and assessing the fisheries impact of anthropogenic activities. Here, we summarize crucial technical details about eDNA metabarcoding for marine fish monitoring and provide meta-analytical trends in primer selection and sample size, assessment standards, fish and fisheries databases, reference fish genomic databases, and other relevant metrics.

Noise characteristics and its influence analysis of the waiting areas in a Chinese children's hospital.

Compared to the general hospital, the children's hospital has significantly higher noise levels. This seriously influences hospital environment quality and medical service level. The noise characteristic and its influence were studied with field measurements and questionnaire surveys conducted in Kunming Children's Hospital.

Enjoy the silence: Canonical and non-canonical RNA silencing activity during plant sexual reproduction.

Plants produce small RNAs that accomplish a surprisingly versatile number of functions. The heterogeneity of functions of plant small RNAs is evident at the tissue-specific level. In particular, in the last years, the study of their activity in reproductive tissues has unmasked an unexpected diversity in their biogenesis and roles.

Green development and co-benefits analysis of a typical chemical industrial park under pollution and carbon reduction and zero-waste city policies.

Industrial parks, under the framework of the "enterprise relocation to parks" policy, have become a crucial cornerstone of China's industrial green development and play a key role in reducing pollution and mitigating carbon emissions . Taking a chemical industrial park in Shanghai as a case study, this study employed the Tapio-CCD model to explore the synergistic relationships among pollutants, and between the economy and pollutants. Additionally, the DDF-Tobit model was used to investigate the impact of Zero Waste City (ZWC) policy and the synergy of carbon and pollution control on green development in the chemical industrial park.

OsAAH confers salt tolerance in rice seedlings.

Soil salinization is becoming a great threat that reduces crop productivity worldwide. In this study, we found that rice allantoate amidohydrolase (OsAAH) expression was significantly upregulated by salt stress, and its overexpression conferred salt tolerance at the seedling stage. Compared to wild type (WT), the contents of ureides (allantoin and allantoate) were significantly increased in Osaah mutants and reduced in OsAAH overexpression lines both before and after salt treatments.

Surgical Face Mask as an Air Sampling Device for Assessing Personal Exposure to Airborne Antimicrobial Resistance Gene-Bearing Bacteria.

In this study, we assessed the feasibility of using a surgical face mask as a sampling device to collect airborne antimicrobial resistance genes (ARGs). The method entails collection of ARG-bearing microbes on face masks, followed by their DNA extraction and quantification by qPCR analysis. Analysis of masks worn by volunteers showed an apparent mask wearing time-dependent accumulation of 16S rRNA gene and select ARGs trapped on masks, highlighting the applicability of the method in monitoring personal ARG exposure through inhalation.

Hop stunt viroid infection induces heterochromatin reorganization.

Viroids are pathogenic noncoding RNAs that completely rely on their host molecular machinery to accomplish their life cycle. Several interactions between viroids and their host molecular machinery have been identified, including interference with epigenetic mechanisms such as DNA methylation. Despite this, whether viroids influence changes in other epigenetic marks such as histone modifications remained unknown.

Allantoate Amidohydrolase OsAAH is Essential for Preharvest Sprouting Resistance in Rice.

Preharvest sprouting (PHS) is an undesirable trait that decreases yield and quality in rice production. Understanding the genes and regulatory mechanisms underlying PHS is of great significance for breeding PHS-resistant rice. In this study, we identified a mutant, preharvest sprouting 39 (phs39), that exhibited an obvious PHS phenotype in the field.

Degree of paraxiality of radially polarized twisted multi-Gaussian Schell-model beams.

The degree of paraxiality (DOP) of a radially polarized twisted multi-Gaussian Schell-model (RPT MGSM) beam is discussed, and the influence of the source parameters on its DOP is studied. It is shown that the parameters of the beam source, including the boundary characteristic, the beam waist width, the coherence width of the source correlation, and the twist factor, have a significant impact on the DOP of the RPT MGSM beam. To explain the behaviors of the DOP, the far-field divergence angle of this beam is also discussed.

Amyloid β oligomer induces cerebral vasculopathy via pericyte-mediated endothelial dysfunction.

Background: Although abnormal accumulation of amyloid beta (Aβ) protein is thought to be the main cause of Alzheimer's disease (AD), emerging evidence suggests a pivotal vascular contribution to AD. Aberrant amyloid β induces neurovascular dysfunction, leading to changes in the morphology and function of the microvasculature. However, little is known about the underlying mechanisms between Aβ deposition and vascular injuries.

Chromatin attachment to the nuclear matrix represses hypocotyl elongation in Arabidopsis thaliana.

The nuclear matrix is a nuclear compartment that has diverse functions in chromatin regulation and transcription. However, how this structure influences epigenetic modifications and gene expression in plants is largely unknown. In this study, we show that a nuclear matrix binding protein, AHL22, together with the two transcriptional repressors FRS7 and FRS12, regulates hypocotyl elongation by suppressing the expression of a group of genes known as SMALL AUXIN UP RNAs (SAURs) in Arabidopsis thaliana.

Proposal of policies based on temporal-spatial dynamic characteristics and co-benefits of CO and air pollutants from vehicles in Shanghai, China.

In megacities, vehicle emissions face urgent challenges related to air pollution and CO control. To achieve the refinement of vehicle control policies for the co-control of air pollutants and CO, this study established a vehicle emission inventory with high spatial and temporal resolution based on the hourly traffic flow in Shanghai and analyzed the spatial and temporal distribution characteristics of the real-time vehicle emissions. Meanwhile, a policy evaluation framework was constructed by combining pollutant emission predictions with quantitative co-control effect assessments.

Progression of cognitive dysfunction in NPC survivors with radiation-induced brain necrosis: A prospective cohort.

Background And Purpose: The evidence of longitudinal changes in cognition in nasopharyngeal carcinoma (NPC) survivors with radiation-induced brain necrosis (RIBN) after radiotherapy (RT) remained insufficient. We aimed to estimate the clinical progression rate of cognitive decline and identify patients with differential decline rates.

Materials And Methods: Based on an ongoing prospective cohort study, NPC patients aged ≥18 years old and diagnosed with RIBN were included in this current analysis if they finished the time frame of 3-year follow-up and had at least twice cognition assessments.

Diel Pattern of Microplastic Residues in Zebrafish.

As one of the emerging pollutants, microplastics (MPs) can be taken up by aquatic organisms through ingestion. However, little is known about the uptake pattern in organisms over time and the associated mechanisms of retention patterns. The present study aims to elucidate these patterns in fish, their relationship with light/dark conditions, and examine the uptake kinetic process of small-sized plastic pollutants, especially during the long-neglected dark period.

Plastic mulching, and occurrence, incorporation, degradation, and impacts of polyethylene microplastics in agroecosystems.

Polyethylene microplastics have been detected in farmland soil, irrigation water, and soil organisms in agroecosystems, while plastic mulching is suggested as a crucial source of microplastic pollution in the agroecosystem. Plastic mulch can be broken down from plastic mulch debris to microplastics through environmental aging and degradation process in farmlands, and the colonization of polyethylene-degrading microorganisms on polyethylene microplastics can eventually enzymatically depolymerize the polyethylene molecular chains with CO release through the tricarboxylic acid cycle. The selective colonization of microplastics by soil microorganisms can cause changes in soil microbial community composition, and it can consequently elicit changes in enzyme activities and nutrient element content in the soil.