Toxicity trends in E-Waste: A comparative analysis of metals in discarded mobile phones.

Mobile phones and various electronic products contribute to the world's fastest-growing category of hazardous waste with international repercussions. We investigated the trends in potential human health impacts and ecotoxicity of waste mobile phones through quantitative life cycle impact assessment (LCIA) methods and regulatory total threshold limit concentrations. A market-dominant sample of waste basic phones and smartphones manufactured between 2001 and 2015, were analyzed for toxicity trends based on 19 chemicals.

Dual function of VGLL4 in muscle regeneration.

VGLL4 has previously been identified as a negative regulator of YAP. Here we show that VGLL4 regulates muscle regeneration in both YAP-dependent and YAP-independent manners at different stages. Knockout of VGLL4 in mice leads to smaller myofiber size and defective muscle contraction force.

A cascade reaction-based switch-on fluorescent sensor for Ce(iv) ions in real samples.

We herein report a cascade reaction-based switch-on fluorescence sensor for Ce(iv) ions. The mechanism is based on the ability of Ce(iv) ions to oxidize β-naphthol, which condenses with -phenylenediamine to generate fluorescent benzo[]phenazine. The sensor achieved a 200-fold fluorescence enhancement and was successfully applied to real sample detection.

Detection and Genetic Characterization of Atypical Porcine Pestivirus in Piglets With Congenital Tremors in Southern China.

Atypical porcine pestivirus (APPV) is an RNA virus newly discovered from swine in Asia, Europe, and the Americas. This novel virus has been confirmed as the cause of congenital tremor (CT) in piglets, which causes extensive economic losses to the swine industry. To investigate the genetic diversity and evolutionary relationship of APPV in China, 83 piglet samples with severe CT clinical signs were obtained from 12 commercial swine farms in 3 provinces of Southern China.

A low-toxicity and high-efficiency deep eutectic solvent for the separation of aluminum foil and cathode materials from spent lithium-ion batteries.

The separation of cathode materials from aluminum (Al) foil is a key issue worthy of attention in the process of resource utilization of spent lithium-ion batteries (LIBs). Traditional technologies for the Al foil and cathode materials separation have the disadvantages of the use of corrosive acid/alkali, release of HF hazards, and environment and healthy risks of the toxicity reagent. In this study, a low-toxicity, high-efficiency, and low-cost deep eutectic solvent (DES), choline chloride-glycerol, was synthesized and applied to solving the separation dilemma of Al foil and cathode materials in spent LIBs.

The association of 6 variants of 8q24 and the risk of glioma: A meta-analysis.

With the advances in sequencing technologies and genome-wide association studies (GWAS), several inherited variants that increase glioma risk have been identified. Ten studies including 8818 cases and 17,551 controls were collected to conduct a meta-analysis to evaluate the associations between 6 variants in 8q24 and glioma risk. Of the 6 variants located in 8q24, 2 have strong significant associations with the risk of glioma, including rs4295627 (P = .

Forecasting the temporal stock generation and recycling potential of metals towards a sustainable future: The case of gallium in China.

Gallium is one such co-product mineral, being used for consumer electronics and contemporary renewable energy applications. China is the top producer of gallium and supplies over 70% of global demand. However, supply uncertainty of primary gallium is increasing due to a shortage of reserves.

Self-Healable Polyelectrolytes with Mechanical Enhancement for Flexible and Durable Supercapacitors.

The practical application of advanced personalized electronics is inseparable from flexible, durable, and even self-healable energy storage devices. However, the mechanical and self-healing performance of supercapacitors is still limited at present. Herein, highly transparent, stretchable, and self-healable poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PAMPSA)/poly(vinyl alcohol) (PVA)/LiCl polyelectrolytes were facilely prepared by one-step radical polymerization.

Neural correlates of appreciating natural landscape and landscape garden: Evidence from an fMRI study.

Introduction: Rambling natural landscapes or landscape gardens may invoke positive emotions. However, the manner in which people experience landscape gardens and the cortical differences in the appreciation of the naturalness and artificiality of landscapes remain unknown.

Methods: This study scanned participants with functional magnetic resonance imaging while they viewed photographs of natural landscapes and landscape gardens and performed scene type judgment task.

Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer.

Background: Apalutamide is an inhibitor of the ligand-binding domain of the androgen receptor. Whether the addition of apalutamide to androgen-deprivation therapy (ADT) would prolong radiographic progression-free survival and overall survival as compared with placebo plus ADT among patients with metastatic, castration-sensitive prostate cancer has not been determined.

Methods: In this double-blind, phase 3 trial, we randomly assigned patients with metastatic, castration-sensitive prostate cancer to receive apalutamide (240 mg per day) or placebo, added to ADT.

Ultrahigh-Rate Behavior Anode Materials of MoSe Nanosheets Anchored on Dual-Heteroatoms Functionalized Graphene for Sodium-Ion Batteries.

MoSe is a prospective anode material for Na-ion batteries because of its layered structure and high theoretical capacity, while the unsatisfied electrochemical performance limits its further development. Herein, we report MoSe nanosheets anchored on dual-heteroatoms functionalized graphene by a solvothermal method. The heteroatoms and carbon matrix coexist in the form of graphitic-N/pyridinic-N/pyrrolic-N and P-C/P═O bonds, which result in excellent electronic conductivity of the materials and provide abundant active sites for electrochemical process.

An RNA-seq-Based Expression Profiling of Radiation-Induced Esophageal Injury in a Rat Model.

Radiation-induced acute injury is the main reason for the suspension of radiotherapy and unsuccessful treatment of cancer. It is of great importance to understand the molecular mechanism of radiation-induced esophageal injury. We used RNA-seq data from normal esophageal tissue and irradiated esophageal tissues and applied computational approaches to identify and characterize differentially expressed genes and detected 40 059 messenger RNAs (mRNAs) previously annotated and 717 novel long noncoding RNAs (lncRNAs).

Direct 800 nm diode-pumped Holmium laser with broad pump wavelength range and temperature adaptability.

We developed an 808 nm diode laser pumped composite Holmium laser via the integration of Tm-doped and Ho-doped YAG crystals into a single bulk structure. A maximum output power of 1.8 W at 2122 nm with near diffraction-limited beam quality was achieved for an absorbed pump power of approximately 7 W.

Rapid and sensitive detection of Senecavirus A by reverse transcription loop-mediated isothermal amplification combined with a lateral flow dipstick method.

Senecavirus A (SVA) is a critical pathogen causing vesicular lesions in sows and acute death of newborn piglets, resulting in very large economic losses in the pig industry. To restrict the transmission of SVA, an establishment of an effective diagnostic method is crucial for the prevention and control of the disease. However, traditional detection methods often have many drawbacks.

Is neutrophil CD11b a special marker for the early diagnosis of sepsis in neonates? A systematic review and meta-analysis.

Objectives: Our study aimed to synthesise and analyse the early diagnostic value of neutrophil CD11b (nCD11b) for neonatal sepsis.

Design: Systematic review and meta-analysis.

Methods: Pubmed, Embase, the Cochrane Library and Web of Science Databases were searched up to June 2018.

Correction: Controlled synthesis of bifunctional particle-like Mo/Mn-NiS/NF electrocatalyst for highly efficient overall water splitting.

Correction for 'Controlled synthesis of bifunctional particle-like Mo/Mn-NiS/NF electrocatalyst for highly efficient overall water splitting' by Yaqiong Gong et al., Dalton Trans., 2019, DOI: 10.

Controlled synthesis of bifunctional particle-like Mo/Mn-NiS/NF electrocatalyst for highly efficient overall water splitting.

Heteroatom-doping engineering has been recognized as an effective strategy to improve the activity and stability of electrocatalytic materials. Herein, we fabricated a bimetallic Mo/Mn codoped three-phase nickel sulfide on Ni foam, with Mo/Mn-NixSy/NF successfully synthesized via hydrothermal synthesis and calcination. In order to better explore the codoping effect of Mo/Mn, we also synthesised Ni3S2/NF, NiS@Ni0.

Sustainable Bioprospecting of Electronic Waste.

Global electronic waste management is emerging as a critical issue, especially in developing countries. Collective societal effort and scientific innovation are required along with interdisciplinary approaches to the development of sustainable technologies for recycling precious metals. Bioprospecting of electronic waste is a promising approach to provide economic, environmental, and public health benefits.

Green tea extract prevents obesity in male mice by alleviating gut dysbiosis in association with improved intestinal barrier function that limits endotoxin translocation and adipose inflammation.

Gut-derived endotoxin translocation provokes obesity by inducing TLR4/NFκB inflammation. We hypothesized that catechin-rich green tea extract (GTE) would protect against obesity-associated TLR4/NFκB inflammation by alleviating gut dysbiosis and limiting endotoxin translocation. Male C57BL/6J mice were fed a low-fat (LF) or high-fat (HF) diet containing 0% or 2% GTE for 8 weeks.

Highly Ordered 3D Porous Graphene Sponge for Wearable Piezoresistive Pressure Sensor Applications.

Wearable sensors with excellent flexibility and sensitivity have emerged as a promising field for healthcare, electronic skin, and so forth. Three-dimensional (3D) graphene sponges (GS) have emerged as high-performance piezoresistive sensors; however, problems, such as limited flexibility, high cost, and low sensitivity, remain. Meanwhile, device-level wearable pressure sensors with GS have rarely been demonstrated.

Increased susceptibility to heat for respiratory hospitalizations in Hong Kong.

Background: Emerging studies have shown temperature-mortality association is changing over time, but little is known about the temporal changes of the temperature-morbidity association.

Objectives: We aimed to evaluate the temporal variations in both temperature-respiratory hospitalizations associations and temperature-related attributable risks in Hong Kong.

Methods: We collected 17-year time-series data on daily ambient temperature and emergency hospital admissions for respiratory diseases between 2000 and 2016 in Hong Kong.

VGLL4 plays a critical role in heart valve development and homeostasis.

Heart valve disease is a major clinical problem worldwide. Cardiac valve development and homeostasis need to be precisely controlled. Hippo signaling is essential for organ development and tissue homeostasis, while its role in valve formation and morphology maintenance remains unknown.

Mechano-microbial systems: An ecofriendly approach for copper bioleaching from waste printed circuit board.

Waste printed circuit board (PCB) is attracting serious concerns because the recycling of its valuable metallic portion is made difficult by the existence of hazardous substances. The objective of the present study was to develop a simplified approach for copper bioleaching from waste PCB. In this context, we intended mechano-microbial systems symbolized as SET-I (spore suspension + potato dextrose broth medium + waste PCB powder), SET-II (pre-cultured until the logarithmic phase, without waste PCB powder), and SET-III (fungal metabolites produced at stationary phase).

Five-year lung cancer mortality risk analysis and topography in Xuan Wei: a spatiotemporal correlation analysis.

Background: In Xuan Wei, China, the lung cancer mortality rate is rising significantly more than that of the nation overall. However, it remains unclear 1) if improved diagnosis can just partially explain this observation and how other local risk factors may be correlated with the lung cancer mortality rate and 2) how the lung cancer mortality rates differ within Xuan Wei and how these spatiotemporal patterns are linked with local risk factors. To increase etiological knowledge, this study evaluated the spatial and temporal distributions of the health effects (the lung cancer mortality rates) from 2011 to 2015.

Occurrence, levels and profiles of brominated flame retardants in daily-use consumer products on the Chinese market.

With the global phasing-out of POP-BFRs (brominated flame retardants restricted under the Stockholm Convention on Persistent Organic Pollutants), the main challenge for their environmentally sound management has shifted from manufacturing and consumption to their recycling and disposal. For the end-of-life products containing POP-BFRs, material recycling and reuse in new articles is the favorite approach widely adopted by recyclers. This would result in POP-BFRs being transferred into daily-use consumer products.