Aluminum decreases cadmium accumulation by down-regulating the expression of cadmium-related genes in wheat.

Aluminum (Al) and cadmium (Cd) often coexist in the acidic soils of southern China, but their interactive effects remain unclear. In this study, this was examined in Al-resistant (Atlas 66) and Al-sensitive (Scout 66) wheat cultivars. The results showed that Al significantly alleviated the root growth of Al-tolerant Atlas 66 under Cd stress but had no effect on the root growth of Al-sensitive Scout 66 or the shoot growth of both cultivars.

Research on improved YOLOV7-SSWD digital meter reading recognition algorithms.

Meter reading recognition is an important link for robots to complete inspection tasks. To solve the problems of low detection accuracy and inaccurate localization of current meter reading recognition algorithms, the YOLOV7-SSWD (YOLOV7-SiLU-SimAM-Wise-IoU-DyHeads) model is proposed, a novel detection model based on the multi-head attention mechanism, which is improved on the YOLOV7-Tiny model. First, the Wise-IoU loss function is used to solve the problem of sample quality imbalance and improve the model's detection accuracy.

Organ donation after brain death from autoimmune glial fibrillary acidic protein astrocytopathy: A case report.

Background: No reports of organ donation have been documented in patients suffering from severe autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.

Case Presentation: A 27-year-old male patient developed a fever and headache, followed a week later by weakness and unsteadiness in his limbs. He attended his local hospital, but no cause was found.

Research progress of robot and laparoscope in postoperative complications of rectal cancer.

Rectal cancer is one of the most common malignant tumours worldwide, and it is also one of the major diseases that seriously threatens human life and health. At present, the main treatment for rectal cancer is still surgical treatment. The surgical methods have been rapidly developed from the previous open surgery to the current minimally invasive surgery.

Lower serum uric acid and impairment of right cerebral hemisphere structural brain networks are related to depressive symptoms in cerebral small vessel disease: A cross-sectional study.

Cerebral small vessel disease (SVD) may be associated with an increased risk of depressive symptoms. Serum uric acid (SUA), an antioxidant, may be involved in the occurrence and development of depressive symptoms, but the mechanism remains unknown. Moreover, the relationship between structural brain networks and SUA has not been explored.

Discontinuity of deep medullary veins in SWI is associated with deep white matter hyperintensity volume and cognitive impairment in cerebral small vessel disease.

Background: Discontinuation of the deep medullary veins (DMVs) may be an early imaging marker for identifying cognitive impairment caused by cerebral small vessel disease (CSVD). However, this method lacks mechanistic exploration. We aimed to investigate whether the DMV score is related to CSVD imaging markers and cognitive impairment in patients with CSVD.

Efficacy and safety of neuromodulation for apathy in patients with Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials.

Background: Non-pharmacological interventions, including noninvasive neuromodulation, may alleviate apathy in individuals with Alzheimer's disease. This systematic review and meta-analysis investigated the efficacy and safety of neuromodulation for apathy in elderly patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI).

Methods: The Cochrane Central Register of Controlled Trials, EMBASE, and PubMed databases were searched for randomized controlled trials (RCTs) of neuromodulation for apathy in AD or MCI.

Distillers' grains organic fertilizer alters soil bacterial composition and co-occurrence patterns in a tobacco-growing field.

In recent years, numerous studies have indicated that the combination of organic and inorganic fertilizers can effectively improve soil fertility and soil productivity. Distillers' grain (DG), the primary by-product of Chinese spirits production, has a high utilization value for producing organic fertilizer. We investigated the effects of distillers' grain organic fertilizer (DGOF) on soil chemical properties and microbial community composition, as well as the effects of chemical properties on the abundance of keystone species.

Aza-dicyclopenta[,]naphthalenes: controllable seesaw-like emissive behavior and narrowband AIEgens.

Molecular motions significantly influence the emissive behavior and properties of organic fluorescent molecules. However, achieving controllable emission remains a major challenge for fluorophores. In the case of aggregation-induced emission luminogens (AIEgens), the desired properties of aggregated emission and narrowband spectrum demand molecular motion patterns that inherently oppose each other.

Multi-scale detection of pulmonary nodules by integrating attention mechanism.

The detection of pulmonary nodules has a low accuracy due to the various shapes and sizes of pulmonary nodules. In this paper, a multi-scale detection network for pulmonary nodules based on the attention mechanism is proposed to accurately predict pulmonary nodules. During data processing, the pseudo-color processing strategy is designed to enhance the gray image and introduce more contextual semantic information.

Bacterial Community Composition and Function of Tropical River Ecosystem along the Nandu River on Hainan Island, China.

Microorganisms play a pivotal role in nutrient cycling in aquatic ecosystems. Understanding bacterial diversity and its functional composition are crucial for aquatic ecology and protection. We investigated the bacterial community structure using 16S rRNA gene amplicons high-throughput sequencing in this study.

Optimal parameter determination of repetitive transcranial magnetic stimulation for treating treatment-resistant depression: A network meta-analysis of randomized controlled trials.

Background: Many studies have shown the efficacy of repetitive transcranial magnetic stimulation (rTMS) in treatment-resistant depression (TRD). However, the choice of different parameters has been a challenging issue.

Methods: PubMed, Cochrane, and Embase databases were searched for relevant studies until June 20, 2022.

A GRIP-1-EZH2 switch binding to GATA-4 is linked to the genesis of rhabdomyosarcoma through miR-29a.

Terminal differentiation failure is an important cause of rhabdomyosarcoma genesis, however, little is known about the epigenetic regulation of aberrant myogenic differentiation. Here, we show that GATA-4 recruits polycomb group proteins such as EZH2 to negatively regulate miR-29a in undifferentiated C2C12 myoblast cells, whereas recruitment of GRIP-1 to GATA-4 proteins displaces EZH2, resulting in the activation of miR-29a during myogenic differentiation of C2C12 cells. Moreover, in poorly differentiated rhabdomyosarcoma cells, EZH2 still binds to the miR-29a promoter with GATA-4 to mediate transcriptional repression of miR-29a.

Palladium-Catalyzed Cascade Reaction in Water to Imidazo[1,2-a]pyridazines as Switchable DSEgens, AIEgens, and ACQgens.

Dual-state emission (DSE) luminophores exhibit strong emissions in both solution and solid states, filling the gaps between aggregation-induced emissions (AIE) and aggregation-caused quenching (ACQ). However, limited design concepts and complicated synthetic strategies restrict the discovery of novel DSE molecules. Developing efficient and green methodologies to access novel DSE scaffolds via rational design remains highly desirable.

Privileged Biorenewable Secologanin-Based Diversity-Oriented Synthesis for Pseudo-Natural Alkaloids: Uncovering Novel Neuroprotective and Antimalarial Frameworks.

Bioprivileged molecules hold great promise for supplementing petrochemicals in sustainable organic synthesis of a diverse bioactive products library. Secologanin, a biorenewable monoterpenoid glucoside with unique structural elements, is the key precursor for thousands of natural monoterpenoid alkaloids. Inspired by its inherent highly congested functional groups, a secologanin-based diversity-oriented synthesis (DOS) strategy for novel pseudo-natural alkaloids was developed.

Direct Transition-Metal Free Benzene C-H Functionalization by Intramolecular Non-Nitroarene Nucleophilic Aromatic Substitution of Hydrogen to Diverse AIEgens.

Direct C(sp )-H functionalization through nitroarene-triggered nucleophilic aromatic substitution of hydrogen (SNAr ) has attracted growing attention, owing to its high efficiency and low carbon footprint. In this study, non-nitro-group-assisted S Ar has been developed for direct benzene functionalization in one pot under mild conditions. The electron-withdrawing carbonyl group and the halide or trifluoromethyl group on the phenyl ring enable the σ adduct formation to fulfill the intramolecular C(sp )-C(sp ) bond construction.

Comparative efficacy and acceptability of neuromodulation procedures in the treatment of treatment-resistant depression: a network meta-analysis of randomized controlled trials.

Background: Nearly half of the patients with depression experience suboptimal benefits from antidepressants. Neuromodulation therapies, a kind of technology that can regulate neuronal firing activity by electrical or magnetic stimulation, were introduced to improve this situation. However, the results from clinical trials have been inconsistent.

Rhodium(iii)-catalyzed cascade reactions of benzoic acids with dioxazolones: discovery of 2,5-substituted benzoxazinones as AIE molecules.

A rhodium-catalyzed cascade reaction of benzoic acids with 1,4,2-dioxazol-5-ones was studied. The carboxyl group enabled a double C-H amidation followed by further intramolecular cyclization to afford 2,5-substituted benzoxazinones, which exhibited aggregation-induced emission (AIE) properties with a promising excited-state intramolecular proton-transfer (ESIPT) phenomenon.

Room-Temperature Phosphorescence in Pure Organic Materials: Halogen Bonding Switching Effects.

Organic room-temperature phosphorescence (ORTP), when combined with external stimuli-responsive capability, is very attractive for sensors and bio-imaging devices, but remains challenging. Herein, by doping two β-iminoenamine-BF derivatives (S-2CN and S-2I) into a 4-iodoaniline (I-Ph-NH ) crystalline matrix, the formation of S-2CN⋅⋅⋅I-Ph-NH and S-2I⋅⋅⋅I-Ph-NH halogen bonds leads to bright-red RTP emissions from these two host-guest doped crystals (hgDCs) with quantum efficiencies up to 13.43 % and 15.

Intravenous lidocaine suppresses dexamethasone-induced perineal pruritus during anesthesia induction: a randomized controlled, double blind study.

Previous studies have found that intravenous dexamethasone may produce perineal pruritus in some patients when administered as premedicant in the preoperative period. This randomized controlled, double-blind study evaluated the efficacy of pretreatment of lidocaine on the incidence and severity of dexamethasone-induced perineal pruritus. 400 patients were enrolled in this study and allocated randomly into four groups (n=100, in each).

[Experimental study on Dendrobium candidum polysaccharides on promotion of hair growth].

Objective: To observe the effect and mechanism of Dendrobium candidum polysaccharides (DCP) in promoting hair growth, in order to lay a foundation for the development and utilization of D. candidum.

Method: The water-extraction and alcohol-precipitation method was adopted to extract DCP, and the phenol-sulphuric acid method was used to determine its content.