Effects of cytoreductive surgery combined with hyperthermic perfusion chemotherapy on prognosis of patients with advanced gallbladder cancer.

Background: Gallbladder cancer (GC) is a common malignant tumor and one of the leading causes of cancer-related death worldwide. It is typically highly invasive, difficult to detect in the early stages, and has poor treatment outcomes, resulting in high mortality rates. The available treatment options for GC are relatively limited.

Contrast-enhanced ultrasonography assessment of gastric cancer response to neoadjuvant chemotherapy.

Aim: To quantitatively assess the ability of double contrast-enhanced ultrasound (DCUS) to detect tumor early response to pre-operative chemotherapy.

Methods: Forty-three patients with gastric cancer treated with neoadjuvant chemotherapy followed by curative resection between September 2011 and February 2012 were analyzed. Pre-operative chemotherapy regimens of fluorouracil + oxaliplatin or S-1 + oxaliplatin were administered in 2-4 cycles over 6-12 wk periods.

[Effects of no-tillage and stubble-remaining on soil enzyme activities in broadcasting rice seedlings paddy field].

A field experiment was conducted to study the effects of four cultivation modes (conventional tillage, no-tillage, conventional tillage + stubble-remaining, and no-tillage + stubble-remaining) on the activities of urease, acid phosphatase, protease, and cellulose in different soil layers in a broadcasting rice seedlings paddy field. Under the four cultivation modes, the activities of test enzymes were higher in upper than in deeper soil layers, and had a greater difference between the soil layers under no-tillage + stubble-remaining. In upper soil layers, the activities of test enzymes were higher in the treatments of no-tillage than in the treatments of conventional tillage, being the highest under no-tillage + stubble-remaining and the lowest under conventional tillage.

[Study on the interaction of Sm(III) complexes of rutin with serum albumin].

The binding reaction of rutin-Sm with serum albumin (SA) was investigated by the fluorescence method in physiological condition. The authors studied mainly the quenching mechanism of the fluorescence of SA by rutin-Sm, and calculation of the binding constants K(LB) of human serum albumin (HSA) and bovine serum albumin (BSA) with rutin-Sm by Lineweaver-Burk equation at different temperatures respectively, then obtained the thermodynamic parameters of HSA and BSA with rutin-Sm according to the calculated binding constants K(LB) at different temperature, meanwhile the type of binding forces of HSA and BSA with rutin-Sm was determined. The results showed that the emission spectra of BSA (HSA) in the presence and absence of rutin-Sm are different.

[Effects of returning straw to soil and different tillage methods on paddy field soil fertility and microbial population].

A field experiment was conducted on a paddy field to study the effects of returning straw to soil and different tillage methods (no-tillage + returning straw, no-tillage, tillage + returning straw, and tillage) on the fertility level and microbial quantities of different soil layers. The results showed that in upper soil layer, the organic matter content in treatment 'no-tillage + returning straw' was 5.33, 2.

[Influence of rutin on conformation of serum albumin].

We studied the effect of the rutin on the conformation of bovine serum albumin (BSA) and human serum albumin (HSA) by synchronous fluorescence spectrum (Alambda = lambda(em) - lambda(ex) = 15 nm and deltalambda = lambda(em) -lambda(ex) = 60 nm) and circular dichroism spectra. The results showed that rutin had hardly effect on the serum protein conformation, but influenced the secondary structure of serum albumin (SA) molecule with the addition of rutin into BSA and HSA solution. The alpha-helix structure of BSA and HSA was decreased and the beta-sheet was increased with the increase in rutin concentration.

[Thermodynamics studies on the binding of rutin and serum albumin].

To study the binding of rutin and serum albumin (SA) in physiological condition and the quenching mechanism of the fluorescence of SA by rutin, the fluorescence method was used. The results shows that the emission spectra of BSA (HSA) in the presence and absence of rutin are different. The emission spectra of BSA (HSA) in the presence of rutin can be quenched.

[Study on the interactions of Eu(III) complex of O-(thioxanthone-[2]-yl)-oxyacetic acid with DNA].

The interaction of the Eu(III) complex of O-(thioxanthone-[2]-yl)-oxyacetic acid and calf thymus DNA was studied using fluorimetric, UV-Vis and CD(circular dichroism) methods. It was found that the ultraviolet absorption intensity of Eu(III) complex of O-(thioxanthone-[2]-yl)-oxyacetic acid decreased as the concentration of DNA increased under the physiological condition of pH 7.10, and the compound remarkably influenced the negative peak in CD spectra of DNA when Eu(III) complex of O-(thioxanthone-[2]-yl)-oxyacetic acid interacted with DNA.