[Optimize extraction technology of Fufang Bajitian Shenggu Particles by central composite design and response surface method].

Objective: To optimize extraction process of Fufang Bajitian Shenggu Particles by central composite design and response surface method.

Methods: The preparation of Fufang Bajitian Shenggu Particles was designed according to the test. With the overall desirability (OD) of Icariin content and the dry extract yield in medicinal materials extract concentrate as examining indexes, immersion time, material liquid ratio, extraction time and stress concentration temperature were investigated.