The value of serum albumin concentration in predicting functional outcome of status epilepticus: An observational study.

Objective: Status epilepticus (SE) is a common neurological emergency with unsatisfying prognoses, and accurate prediction of functional outcome is beneficial in clinical decision-making. The relationship between serum albumin concentration and outcome of SE patients has yet to be unveiled.

Methods: Clinical profiles of SE patients admitted to Xiangya Hospital, Central South University, from April 2017 to November 2020, were analyzed retrospectively.

Spectrum of neuroimaging findings in cryptococcal meningitis in immunocompetent patients in China - A series of 18 cases.

Purpose: Cryptococcosis is a devastating opportunistic disease commonly encountered in organ transplant recipients and patients with acquired immunodeficiency syndrome (AIDS). Few studies have profiled the disease in immunocompetent patients. We sought to characterize the neuroimaging findings of cryptococcal meningitis among immunocompetent patients in China.

Tenuigenin attenuates α-synuclein-induced cytotoxicity by down-regulating polo-like kinase 3.

Background And Aims: Tenuigenin (Ten) is a Chinese herbal extract with antioxidative and antiinflammatory effects on toxin-induced cell models of Parkinson's disease (PD); however, its effects on α-synuclein toxicity-based PD models remain unknown. α-synuclein hyperphosphorylation is a key event in PD pathogenesis and potential target of therapeutic interventions. We tested whether Ten alleviates α-synuclein-induced cytotoxicity via reducing kinases that phosphorylate α-synuclein.

[Callus cultivation and determination of gentiopicroside from Gentiana macrophylla].

Objective: To explore and improve the utilization efficiency of Gentiana macrophylla resources.

Methods: The germination of Gentiona macrophylla seeds were used as explants to induce calluses; Cultured on various culture media and condition for callus induction and subculture by test; The content of gentiopicroside in callus was determined by HPLC.

Results: The optimum medium for callus was MS +2,4-D (1.

[Fine mapping of a pure paroxysmal kinesigenic dyskinesia family].

Objective: To fine map the gene responsible for pure paroxysmal kinesigenic dyskinesia in a Chinese family.

Methods: Six additional markers flanking the tightly linked markers were chosen in the candidate region resulting from a whole genome-wide scanning and tested by parameter and nonparameter analysis using Linkage and Genehunter softwares to fine map the candidate region.

Results: Evidence for linkage of the pure paroxysmal kinesigenic dyskinesia to chromosome 3 was further confirmed.

[Clinical features and prognosis of cerebral venous thrombosis].

Objective: To explore the diagnosis,therapy and prognosis of cerebral venous thrombosis (CVT).

Methods: Twenty-two CVT patients were reviewed. The onset age, clinical manifestations, imaging, treatment, and prognosis were analyzed.