Publications by authors named "Jin-jun Xu"
Article Synopsis
- Histomonosis is a protozoan disease that affects poultry and causes significant economic losses in China, prompting the development of an attenuated vaccine based on a less virulent strain.
- Four experiments were conducted to test the viability of the attenuated strain, including comparing different infection routes, doses, and immunization schedules to determine the most effective vaccination strategy.
- Results indicated that the intracloacal route was more effective than oral administration, particularly with a vaccination dose of 2 × 10 on day 14, which led to better weight gain and fewer health issues in vaccinated chickens.
Introduction: can cause histomonosis in poultry. Due to the prohibition of effective drugs, the prevention and treatment of the disease requires new strategies. Questions about its pathogenic mechanisms and virulence factors remain puzzling.
View Article and Find Full Text PDFBackground: Histomonas meleagridis is an anaerobic, intercellular parasite, which infects gallinaceous birds such as turkeys and chickens. In recent years, the reemergence of Histomoniasis has caused serious economic losses as drugs to treat the disease have been banned. At present, H.
View Article and Find Full Text PDFThe shear transfer mechanism of steel fiber reinforced concrete (SFRC) beams without stirrups is still not well understood. This is demonstrated herein by examining the accuracy of typical empirical formulas for 488 SFRC beam test records compiled from the literature. To steer clear of these cognitive limitations, this study turned to artificial intelligence (AI) models.
View Article and Find Full Text PDFThe current methods of treating toxoplasmosis have a number of side effects, and these therapies are only effective against the acute stage of the disease. Thus, development of new low toxicity and efficient anti- drugs is extremely important. Natural products are important sources for screening new drugs; among them, essential oils (EOs) have efficacy in anti-bacterial, anti-inflammatory, anti-insect, and other aspects.
View Article and Find Full Text PDFArticle Synopsis
- - Toxoplasma gondii is a widespread parasitic protozoan primarily transmitted to humans through infected pigs and oocysts from cats, with a study conducted in Jiangsu Province revealing high infection rates in both sick pigs (46.81%) and stray cats (34.38%) using PCR and ELISA methods.
- - The study identified that T. gondii was significantly more prevalent in the lungs and heart of pigs compared to their liver and spleen, and factors like age and geographic location contributed to the infection rates.
- - Six distinct genetic variants of T. gondii were identified, with the most common being the Chinese I genotype, alongside the first report of two new genotypes (New 1 and New 2
[Effect of Toxoplasma gondii Infection in Female Mice on Dopamine Level in the Brain of the Male Offspring].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
February 2015
Objective: To investigate the effect of Toxoplasma gondii infection in female mice on dopamine level in the brain of male offspring.
Methods: Thirty-six ICR female mice were randomly divided into control group and infection group, 18 mice in each group. Each mouse in infection group was orally infected with 10 cysts of T.
[Observation of animal model of life cycle of Angiostrongylus cantonensis].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
December 2014
Objective: To observe the effect of artificially construction of the life cycle of Angiostrongylus cantonensis in the laboratory condition, so as to provide the basis for the research of angiostrongyliasis.
Methods: SD rats were infected orally with the third-stage larvae of A. cantonensis collected from infected Pomacea canaliculata.
[High level expression of recombinant chicken interferon-gamma in insect cells].
Wei Sheng Wu Xue Bao
October 2005
The recombinant transfer vector pFastBacl-ChIFN-y was constructed by plasmid pcDNA-ChIFN-gamma digested with EcoR I and Not I enzymes and cloned into pFastbacl. Then the transfer vector was transformed into E. coli competent cells DH10Bac which contained the bacmid with amini-attTn7 target site and the helper plasmid.
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