Publications by authors named "Jin-jia Zhang"
Species of the family Microdochiaceae (Xylariales, Sordariomycetes) have been reported from worldwide, and collected from different plant hosts. The proposed new genus and two new species, , , and , are based on multi-locus phylogenies from a combined dataset of ITS rDNA, LSU, RPB2 and TUB2 with morphological characteristics. has been collected from diseased leaves of and this is the first report of the fungus on this host plant.
View Article and Find Full Text PDF[Advances in traditional Chinese medicine treatment of non-alcoholic fatty liver disease via farnesoid X receptor].
Zhongguo Zhong Yao Za Zhi
December 2023
Article Synopsis
- Non-alcoholic fatty liver disease (NAFLD) is a growing global health issue due to its rising prevalence as a chronic metabolic condition.
- Research shows that targeting the farnesoid X receptor (FXR) can enhance liver function and metabolic health in NAFLD patients, making it a promising avenue for drug development.
- This paper reviews how traditional Chinese medicines and their active components interact with FXR to treat NAFLD, highlighting their safety and effectiveness while identifying potential targets for future drug development.
Background: Oxidative stress and neuroinflammation play crucial roles in the progression of neonatal hypoxic-ischemic brain damage (HIBD). Genistein, a natural phytoestrogen, has been found to protect against ischemic brain injury. However, its effects and potential mechanisms in HIBD have not yet been explored.
View Article and Find Full Text PDFPrevious studies have demonstrated that the activation of delta opioid receptors is neuroprotective against neonatal hypoxia-ischemia (HI) brain injury. The aim of this study was to investigate the neuroprotective effects of biphalin, a dimeric opioid peptide, in a mouse model of neonatal HI and the underlying mechanisms. On postnatal day 10, mouse pups were subjected to unilateral carotid artery ligation followed by 1 h of hypoxia (10 % O in N).
View Article and Find Full Text PDF[Optimization of induction and culture conditions for hairy roots of Salvia miltiorrhiza].
Zhongguo Zhong Yao Za Zhi
August 2014
To establish induction and liquid culture system for hairy roots of Danshen (Salvia miltiorrhiza), Agrobacterium rhizogenes A4, LBA9402, 15834 as test bacterium were used to infect aseptic leaves of Danshen. The hairy roots were induced and positive transgenic hairy roots were selected with PCR using rolB and rolC as the target gene. Then hairy roots of S.
View Article and Find Full Text PDFArticle Synopsis
- - Researchers produced hairy roots from Danshen (Salvia miltiorrhiza) by infecting its leaves with Agrobacterium rhizogenes, leading to the generation of various beneficial compounds, including salvianolic acids.
- - The study evaluated how methyl jasmonate (MeJA) and yeast elicitor (YE) influenced the levels of these compounds; MeJA generally enhanced their accumulation, while YE promoted some but suppressed others.
- - Findings suggest that these hairy roots are a promising alternative source for producing salvianolic acids and imply that salvianolic acid K and a compound with a molecular weight of 538 may play a role in transforming rosmarinic acid to salvianolic acid B. *