Publications by authors named "Jin-hui Tan"
[Efficacy of local injection of RhTNFR: Fc in collagen-induced arthritis of rats].
Zhonghua Yi Xue Za Zhi
October 2013
Objective: To evaluate the efficacy of recombinant human tumor necrosis factor-α receptor II: IgG fusion protein (RhTNFR:Fc) local injection in collagen-induced arthritis (CIA) of rats.
Methods: Twenty-four CIA rats were randomly divided into 3 groups: single therapy (Group I), multiply therapies (Group II) and control (Group III). Group I received normal saline thrice after a single RhTNFR:Fc local treatment while Groups II and III had 4 times of RhTNFR:Fc or normal saline local injection.
Article Synopsis
- Ankylosing spondylitis (AS) is a common inflammatory disease with limited treatment options, and this study investigates the impact of the alkaloid sinomenine (SIN) on patients' peripheral blood mononuclear cells (PBMCs).* -
- The study involved 30 AS patients whose PBMCs were tested with and without SIN; results showed changes in the expression of various proteins linked to apoptosis and immune function.* -
- Eight proteins were identified as differentially expressed in SIN-treated PBMCs, providing insights into how SIN may work in treating AS.*