Publications by authors named "Jin-guo Zheng"
[Prognostic value of admission B-type natriuretic peptide on outcome for patients with congestive heart failure].
Zhonghua Xin Xue Guan Bing Za Zhi
June 2012
Objective: To observe the prognostic value of admission B-type natriuretic peptide (BNP) on outcome for patients with congestive heart failure (CHF).
Methods: Blood BNP levels, routine echocardiography and tissue Doppler image were obtained in 162 CHF patients [95 male, mean age: (71.8±3.
There is an accumulating body of evidence indicating a strong association between inflammation and the pathogenesis of atrial fibrillation (AF). Interleukin-6 (IL-6) is a pleiotropic cytokine, functions as a mediator of inflammatory response, and has both proinflammatory and anti-inflammatory properties. The aim of the present study was to investigate the association of the -634C/G polymorphism of the IL-6 gene with AF in elderly Han Chinese patients with essential hypertension (EH).
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- * A study investigated the connection between interleukin 6 (IL-6) gene variations and thrombus presence in Han Chinese patients with AF, finding significant differences between those with and without thrombus.
- * The results showed that G allele carriers (CG + GG genotypes) have a significantly higher risk of developing thrombus or severe spontaneous echocontrast compared to those with the CC genotype, highlighting the G allele's role as an independent risk factor.
Interleukin-6 (IL-6) is a cytokine involved in different physiologic and pathophysiologic processes including essential hypertension (EH). Associations of the IL-6 promoter region polymorphisms with circulating level of IL-6 have been reported in various studies. We detected the IL-6-597G/A polymorphism in 246 EH patients and 194 healthy controls from Jiangsu area (south of China).
View Article and Find Full Text PDFBackground: Interleukin 6 (IL-6) is a cytokine involved in different physiologic and pathophysiologic processes, and circulating levels of IL-6 differ greatly between individuals, but the results have not always been concordant among diverse populations. The aim of present study was to determine the prevalence of the 3 polymorphisms (-174G/C, -597G/A, and -634C/G) in the IL-6 gene promoter region and their effects on inflammatory markers in normal Han Chinese population.
Methods: A total of 232 subjects (143 men and 89 women; mean age, 51.