Publications by authors named "Jin-fu Liu"

Background: (CR) is widely used in traditional Chinese medicine to prevent and treat a variety of diseases. However, its functions and mechanism of action in osteoarthritis (OA) has not been elucidated. Here, a comprehensive strategy combining network pharmacology, molecular docking, molecular dynamics simulation and in vitro experiments was used to address this issue.

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Osteoarthritis (OA) is a chronic joint disease that reduces quality of life for patients. Ferroptosis plays a significant role in OA. However, its underlying mechanism remains unclear.

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The typical river-lake ecotone (tail end area) of Poyang Lake, which is a sensitive area and prone to outbreaks of cyanobacteria bloom, is vulnerable to frequent human activities. To explore the diversity of phytoplankton community structure and the relevant driving mechanism in the typical river lake junction area of Poyang Lake, the water quality and phytoplankton at seven sampling points in the typical river lake junction area of Poyang Lake, at six sampling points in the middle section of Poyang Lake River, and at one sampling point in the main lake area were investigated in the field from 2019 to 2020 (dry season), April (flood season), July (wet season), and October (recession period). The results showed that there were seven phyla and 64 genera of phytoplankton in the typical river-lake ecotone of Poyang Lake, and the biomass and relative abundance of phytoplankton were dominated by diatoms and cyanobacteria.

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Article Synopsis
  • The survival rate of seedlings from seed is low, complicating the regeneration of natural forests, and the study focuses on how forest gaps affect this process.
  • The research examined different sized forest gaps (large, medium, small) and their positions, finding that medium gaps had the highest seed germination rates and radicle growth.
  • Key factors influencing seed success were found to be canopy openness and air temperature, leading to the conclusion that medium gaps are optimal for growing endangered species in the studied forest.
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When seeds fallen from the mother trees, their initial contact physical environment was litter or soil. The dispersal positions of seeds (seeds positioned on top of the litter, the soil surface and beneath the litter) determine the process of their natural regeneration. We simulated three different dispersal positions of , including seeds positioned on top of the litter (2 and 4 cm litter was placed below the seed layer), soil surface (without litter), and seeds beneath the litter (2, 4, 6 and 8 cm litter covers in the upper layer of seeds).

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The tumor microenvironment (TME) has important effects on the tumorigenesis and development of osteosarcoma (OS). However, the dynamic mechanism regulating TME immune and matrix components remains unclear. In this study, we collected quantitative data on the gene expression of 88 OS samples from The Cancer Genome Atlas (TCGA) database and downloaded relevant clinical cases of OS from the TARGET database.

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Article Synopsis
  • A rare plant species in Yun-xiao County, Fujian Province, has a critically low population consisting of only 25 individuals, mainly young seedlings, and just one mature mother tree.
  • The spatial distribution shows most seedlings are clustered within 10-25 meters of the mother tree, indicating an unsustainable population due to lack of older trees and intense competition from surrounding species.
  • An evaluation of this plant's conservation status reveals it is classified as "extremely endangered" with high protection value and priority, suggesting immediate conservation actions are necessary.
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Urbanization usually pollutes the environment leading to alterations in key biogeochemical cycles. Therefore, understanding its effects on forest nitrogen (N) saturation is becoming increasingly important for addressing N pollution challenges in urban ecosystems. In this study, we compared soil (N availability, net N mineralization, net nitrification, and δN) and foliar (N concentrations and δN) variables in upstream, midstream and downstream forest stands of Bailongjiang River (BJR; more urbanized) and Wulongjiang River (WJR; less urbanized), the two branches of the Minjiang River Estuary.

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Objective: To study the effect of Bifidobacterium on the expression of β-defensin-2 (BD-2) in intestinal tissue of neonatal rats with necrotizing enterocolitis (NEC).

Methods: A total of 40 rats were randomly divided into four groups: normal control, Bifidobacterium control, NEC model, and Bifidobacterium treatment, with 10 rats in each group. A rat model of NEC was induced by hypoxia, cold stimulation, and artificial feeding.

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Designing the nature reserves is an effective approach to protecting biodiversity. The traditional approaches to designing the nature reserves could only identify the core area for protecting the species without specifying an appropriate land area of the nature reserve. The site selection approaches, which are based on mathematical model, can select part of the land from the planning area to compose the nature reserve and to protect specific species or ecosystem.

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  • A genome-shuffled strain of Candida versatilis S3-5 was tested for its fermentation performance during soy sauce production compared to a wild-type strain.
  • The S3-5 strain produced ethanol more rapidly and in larger quantities than the WT, along with higher levels of organic acids like malic, citric, and succinic acids.
  • Additionally, S3-5 generated significantly more flavor compounds, particularly esters, suggesting it has better metabolic capabilities and could be beneficial as a salt-tolerant yeast in fermentation processes.
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As one of the major microbes in the soy sauce fermentation, Candida versatilis enriches the flavor and improves the quality of soy sauce. In this study, a combination of five different GC-MS and LC-MS-based metabolome analytical approaches was used to analyze the intracellular, extracellular and whole metabolites of C. versatilis.

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Background: This study aimed to enhance and improve the quality and safety of soy sauce. In the present work, the change of biogenic amines, such as histamine, tyramine, cadaverine, spermidine, was examined by the treatment of Candida versatilis and Zygosaccharomyces rouxii, and the influence of salt-tolerant yeast on biogenic amines was analysed during the whole fermentation process.

Results: The results showed that the content of biogenic amines was elevated after yeast treatment and the content of biogenic amines was influenced by using yeast.

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Glyptostrobus pensilis is a rare and endangered relict species in China. To make a comparative study on the genetic diversity and genetic structure of natural and planted G. pensilis populations would have significance in the conservation and proliferation of the species.

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The effect of H(2)O(2) supplement on cell growth and β-carotene productions in recombinant Saccharomyces cerevisiae CFW-01 and CFW-01 ctt1 deficiency in cytosolic catalase were investigated in shaking flasks. The results showed that supplement of H(2)O(2) (0.5 and 1.

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