[Relationship between polymorphism of interleukin-1 and pneumoconiosis susceptibility].

Objective: To explore the relationship between the polymorphism of Interleukin-1 and the pneumoconiosis susceptibility.

Methods: Eighty patients with silicosis and 45 with coal workers' pneumoconiosis (CWP) were selected while 125 male workers, Han nationality in the same workplace as the patients were selected as the controls. Between the patients and the control, the differences of age and cumulative length of service were less than five years and two years, respectively.

[Relationship between polymorphisms of DNA repair gene XRCC1 and susceptibility to radiation injury].

Objective: To explore the relationship between polymorphisms of DNA repair gene XRCC1 and susceptibility to radiation injury.

Methods: In 1:1 case-control study, 113 abnormal chromosome workers exposed to ionizing radiation were selected as cases and 113 normal chromosome as controls who matched with case for sex, age (+/- 5 years), nation, type of work, the same or more but in 2 years work length and the same similar levels of the cumulative exposure radiation dose. Genotypes were analysed using PCR based restriction fragment length polymorphism techniques.

[Relationship between pneumoconiosis and the polymorphisms of HLA-DRB1*, DQB1* genes].

Objective: To explore the relationship between the polymorphism of HLA-DRB1*, DQB* genes and the susceptibility of pneumoconiosis.

Methods: 1:1 case-control study was adopted. one hundred and thirteen cases of I grade pneumoconiosis were investigated.