Three-dimensional-arterial spin labeling perfusion correlation with diabetes-associated cognitive dysfunction and vascular endothelial growth factor in type 2 diabetes mellitus rat.

Background: Type 2 diabetes mellitus (T2DM) has been strongly associated with an increased risk of developing cognitive dysfunction and dementia. The mechanisms of diabetes-associated cognitive dysfunction (DACD) have not been fully elucidated to date. Some studies proved lower cerebral blood flow (CBF) in the hippocampus was associated with poor executive function and memory in T2DM.

[Anatomical study of improved lateral arm free flap].

Objective: To study the anatomy and preparation methods of an improved lateral arm free flap (LAFF) for the future clinical application.

Methods: Twenty-two adult upper extremities from cadavers after injected with red latex through common carotid arteries were used. The course, branches, distribution and variations of the blood vessels and nerves of the improved LAFF were observed.

[Expression and clinical significance of P-gp in colonic gland of chronic schistosomiasis patients].

Objective: To study the expression of P-glycoprotein (P-gp) in patients with chronic schistosomiasis and its relationship with gender and age, and to explore its clinical significance.

Methods: The colonic mucosa specimens of 50 chronic schistosomiasis patients and 4 persons who had a family history of colon cancer but their physical examinations were normal (as a control group) were selected and the expressions of P-gp in the colonic gland of these samples were detected with the immunohistochemical staining method.

Results: Compared with the control group, the mean gray value of the positive particles of P-gp of colonic epithelial cells of the chronic schistosomiasis group was significantly reduced (P < 0.

[Endogenous BDNF promote regeneration of injured nervous system].

Objective: To test the effect of endogenous BDNF on injured nervous system.

Methods: The left sciatic nerves of the rats were cut off, and then divided into two groups, each with 8 rats. The rats in the experimental group were intraperitoneally injected with anti-BDNF, while the control group was given normal sheep serum (NSS).