Reconstruction of beagle hemi-mandibular defects with allogenic mandibular scaffolds and autologous mesenchymal stem cells.

Objective: Massive bone allografts are frequently used in orthopedic reconstructive surgery, but carry a high failure rate of approximately 25%. We tested whether treatment of graft with mesenchymal stem cells (MSCs) can increase the integration of massive allografts (hemi-mandible) in a large animal model.

Methods: Thirty beagle dogs received surgical left-sided hemi-mandibular defects, and then divided into two equal groups.

[Application of computer-aided surgery in fibrous dysplasia of cranio-maxillofacial bone].

Purpose: To evaluate the effect of computer-aided surgical techniques in surgical treatment of cranio-maxillofacial fibrous dysplasia.

Methods: Twenty-two patients from January 1999 to December 2012 with cranio-maxillofacial fibrous dysplasia were treated in our department. According to the patients' specific conditions, surgeons designed surgical programs, and used computer-assisted surgical techniques to produce skull model and navigation template individually.

[Early reconstruction of the periorbital injuries].

Objective: To study the clinical characteristics and the treatment of periorbital injuries.

Methods: 61 cases were treated, including 30 cases orbitozygomatic fracture, 6 cases of frontal-orbital fracture, 8 cases of naso-ethmoid-orbital fracture, 7 cases of blow -out fracture and 10 cases of complicated fracture. The patients were diagnosed after physical examination and other examination, like CT.

[Genioplasty with two-step osteotomy for severe microgenia].

Objective: To investigate a technique for correction of severe microgenia.

Methods: The mandibular symphysis was exposed through intraoral mucous incision. Two parallel osteotomies were performed under mental foramen.

[Analysis of the complications following mandibular distraction using internal distractors].

Objective: To investigate the causes and the prophylactic for the complications following mandibular distraction osteogenesis using internal distractors.

Methods: From 1997 to 2004, a total of 46 patients (61 sides) suffering from malformations or defects of mandible who underwent mandibular distraction osteogenesis were analyzed. The diseases included hemifacial microsomia in 27 cases, congenital or acquired mandibular hypoplasia and micrognathia bilateral in 8 cases and unilateral in 4 cases, electronical injury or postoperative mandibular defects in 3 cases, Treacher Collins syndrome in 2 cases, obstructive sleep apnea syndrome in 2 cases.

[Surgical management of craniomaxillofacial fibrous dysplasia].

Objective: To explore the method to obtain good aesthetic and functional results in surgical management of craniomaxillofacial fibrous dysplasia and correct the grotesque deformity.

Methods: According to the type of the lesions, different excision and reconstruction methods were used.

Results: 19 cases (4 monostotic cases and 15 polyostotic cases) were surgically treated.

[Surgical treatment of orbital and periorbital fibrous dysplasia].

Objective: To explore the surgical approaches to obtain good aesthetic and functional results in the management of orbital and periorbital fibrous dysplasia and related deformities.

Methods: Ten cases of orbital and periorbital fibrous dysplasia were treated surgically. The location, extension and shape of the lesions were identified based on X-ray examination and two and three dimensions CT examinations preoperatively.

[Applications of autogenous outer table of the calvarial and mandibular bone in posttraumatic deformities of the nose].

Objective: To study the applications of bone grafts from the cranium or mandible in the repair of posttraumatic deformities of the nose.

Methods: From 1997 to 2002, a total of 44 patients, who presented with secondary nose deformity as well as facial fractures, were reconstructed by autogeneous outer table grafts of the calvarial or mandibular bone after facial skeleton reposition. In this series, 32 cases used the calvarial bone, 12 cases used the mandible bone, which was harvested through a coronal incision and an oral approach respectively.

[Chin augmentation with bone transplantation from the mandible].

Objective: To explore a new method for mentoplasty.

Methods: The bilateral prominent mandibular angle or outer lamina was resected through the intraoral approach. The resected bone fragments were shaped and rigid fixed to the chin with miniplates and screws.

[Individual prefabricated titanium implant for the reconstruction of the skull bone defect].

Objective: This paper presents a new method of individual prefabricated titanium implant for the reconstruction of the skull bone defect.

Method: A computer-based 3D model of the cranial bone defect is created from helical CT-data and serves as the basis for the computer aided design and manufacturing (CAD/CAM) of the individual prefabricated titanium implant for the cranial bone defect reconstruction.

Result: Since 2001, a total of nine patients suffering from the cranial bone defect have been operated on by this method with satisfied result.

[Compositive treatment of square face].

Objective: To investigate the treatment of square face with compositive methods. METHODS A total of 71 patients with square-shape face were treated. According to the different face skeleton and desire of patient, mandible angle curved-osteotomy and mentoplasty were used as main methods and zygomatoplasty, buccal fat pad resecting and other aesthetic methods as assistant methods to recontour the whole face skeleton.

[Secondary reconstruction of post-fracture deformities in the nasal-orbital ethmoid region].

Objective: To study the surgical reconstruction of secondary fracture deformities of the nasal-orbital ethmoid area.

Methods: Typical bicoronal and subciliary incisions or the adjacent scar incision were employed to expose the fractured area. The flattened nasal bone was narrowed by curved osteotomy along the medial orbital rims and trimed with a bur.