[Clinicopathologic analysis of cervical lymph node metastasis in 708 patients with oral squamous cell carcinoma].

Purpose: To investigate the characteristics of cervical lymph node metastasis in oral squamous cell carcinoma (OSCC), and the relationship between clinicopathologic factors of OSCC and cervical lymph node metastasis (CLNM).

Methods: Clinicopathologic data of 708 patients with OSCC who underwent neck dissection were retrospectively analyzed. The relationship between clinicopathologic factors of OSCC and CLNM was analyzed with univariate analysis and multivariate analysis using SPPPSS19.

Application of molecular imaging technologies in antitumor drug development and therapy.

Molecular imaging enables noninvasive characterization, quantification and visualization of biological and pathological processes in vivo at cellular and molecular level. It plays an important role in drug discovery and development. The skillful use of molecular imaging can provide unique insights into disease processes, which greatly aid in identifications of target.

Chimeric flaps pedicled with the lateral circumflex femoral artery for individualised reconstruction of through-and-through oral and maxillofacial defects.

Reconstruction of through-and-through oral and maxillofacial defects has always been difficult. We have evaluated the feasibility and reconstructive efficacy of chimeric flaps pedicled with the lateral circumflex femoral artery in the reconstruction of 41 through-and-through oral and maxillofacial defects after resections for cancer. There were 29 chimeric anterolateral thigh and anterolateral thigh flaps and 12 chimeric anterolateral thigh and anteromedial thigh flaps, the sizes of which ranged from 5×8 to 9×11 cm.

[Preparative technique of anterolateral thigh flap].

Objective: To investigate the surgical techniques and methods of anterolateral thigh (myocutaneous) flap.

Methods: Two hundred and forty-five consecutive free anterolateral thigh (myocutaneous) flaps for reconstruction of the defects of oral and maxillofacial region following the malignant tumors resection from January 2007 to August 2009 were reviewed. The incision was designed in the upper, middle or lower part 3 cm medial of the iliac-patella line according to the thickness of flaps needed.

[The chimeric perforator flap pedicled with descending branch of lateral circumflex femoral artery for reconstruction of oromaxillary soft tissue defect].

Objective: To report the application of the chimeric perforator flap pedicled with descending branch of lateral circumflex femoral artery for large and complicated oromaxillary soft tissue defect.

Methods: Based on the anatomic study of descending branches and cutaneous perforators of lateral circumflex femoral artery, the perforator vessels were found and used as flap pedicle. The perforator flap was made as chimeric flap for repairing the oromaxillary soft tissue defect in 8 cases.

[Clinical application of free anterolateral thigh flap in the reconstruction of oromaxillo-facial defects].

Objective: To analyze the possibility and practicality of using free anterolateral thigh flap to repair defects of oromaxillo-facial region.

Methods: One hundred and seventy-two patients underwent anterolateral thigh flap (ALP) reconstruction from Jan. 2007 to Dec.