Publications by authors named "Jin-Zhao Xie"

Aim: Robotic-assisted pancreatectomy has been widely used. Organ-preserving pancreatectomy (OPP) and parenchymal-sparing pancreatectomy (PSP) has been gradually adopted for pancreatic benign or low-grade malignant tumors. This study aimed to evaluate the safety and efficacy of robotic-assisted OPP/PSP in our institute.

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Article Synopsis
  • RSVP-SPDP is a surgical technique that preserves the spleen during distal pancreatectomy and shows a lower splenic infarction risk compared to the traditional method, though it's more complex.
  • A study analyzed 74 patients, finding a significant improvement in operation time and blood loss after the surgeon's 16th case, although some other metrics didn't show significant changes.
  • The results suggest that RSVP-SPDP is a safe and effective option for specific patients once the surgeon has overcome the learning curve associated with the procedure.
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Objectives: To develop a computed tomography (CT) radiomics-based interpretable machine learning (ML) model to predict the pathological grade of pancreatic neuroendocrine tumors (pNETs) in a non-invasive manner.

Methods: Patients with pNETs who underwent contrast-enhanced abdominal CT between 2010 and 2022 were included in this retrospective study. Radiomics features were extracted, and five radiomics-based ML models, namely logistic regression (LR), random forest (RF), support vector machine (SVM), XGBoost, and GaussianNB, were developed.

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Article Synopsis
  • The study evaluated the outcomes and learning curves of robotic-assisted pancreatoduodenectomy (RPD) performed by a single surgeon over a six-year period.
  • Significant reductions in surgery times for both resection and reconstruction were observed after the surgeon completed 30 and 45 cases, respectively.
  • The procedure demonstrated safety with improved intraoperative blood loss and a decrease in post-operative complications as the surgeon gained experience.
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Background: The application of robotic-assisted radical resection in perihilar cholangiocarcinoma (pCCA) remains poorly defined. This study aimed to evaluate the safety and efficacy of robotic-assisted radical resection for pCCA in our institute.

Methods: Between July 2017 and July 2022, pCCA patients undergoing robotic-assisted and open radical resection at First Affiliated Hospital of Sun Yat-sen University (Guangzhou, China) were included.

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Background And Objective: The value of debulking surgery for unresectable well-differentiated metastatic pancreatic neuroendocrine tumor (m-PNET) remains poorly defined. This study aimed to evaluate the outcomes of m-PNET following debulking surgery in our institute.

Methods: Patients with well-differentiated m-PNET in our hospital between February 2014 and March 2022 were collected.

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Background: The feasibility of spleen-preserving distal pancreatectomy (SPDP) to treat well-differentiated non-functioning pancreatic neuroendocrine tumors (NF-pNETs) located at the body and/or tail of the pancreas remains controversial. Distal pancreatectomy with splenectomy (DPS) has been widely applied in the treatment of NF-pNETs; however, it may increase the post-operative morbidities. This study aimed to evaluate whether SPDP is inferior to DPS in post-operative outcomes and survivals when being used to treat patients with NF-pNETs in our institute.

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Background: Routine lymphadenectomy in pancreatic neuroendocrine tumors (pNETs) is debated. There lacks accurate model to predict lymph node metastasis (LNM) preoperatively in pNETs. Therefore, this study aimed at developing a nomogram in predicting LNM in pNETs preoperatively.

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