Publications by authors named "Jin-Yu Shew"
Article Synopsis
- The study investigates the diversity of cancer stem/progenitor cells in breast cancer, paralleling findings already established in leukemia, by analyzing various stem cell markers in human breast cancer cell lines and primary samples using flow cytometry.
- Results showed that different breast cancer cell lines exhibited significant variation in stem cell marker expression, highlighting that traditional markers like CD44(+)/CD24(-/low) and ALDH may not be the most effective for identifying cancer stem cells in all cases.
- Notably, the research identified PROCR and ESA as more reliable markers for enriching stem/progenitor cell populations in certain breast cancer cell lines, demonstrating their potential for self-renewal and tumorigenicity, as well as a correlation between marker expression
