The Effect of Time Spent on Online Gaming on Problematic Game Use in Male: Moderating Effects of Loneliness, Living Alone, and Household Size.

Objective: This study aimed to investigate the association between gaming time and problematic game use (PGU) within a large sample of Korean male gamers and to examine the potential moderating effects of loneliness, living alone, and household size.

Methods: This study employed data from 743 male gamers from the National Mental Health Survey 2021, a nationally representative survey of mental illness conducted in South Korea. Self-reported data on the average gaming time per day, severity of PGU, loneliness, living alone, and household size were used.

Preventing Risks of Infections and Medication Errors in IV therapy (PRIME): a patient safety initiative.

Background: Two major avoidable reasons for adverse events in hospital are medication errors and intravenous therapy-induced infections or complications. Training for clinical staff and compliance to patient safety principles could address these.

Methods: Joint Commission International (JCI) consultants created a standardised, 6-month training programme for clinical staff in hospitals.

Reduction of Ethyl Carbamate in an Alcoholic Beverage by CRISPR/Cas9-Based Genome Editing of the Wild Yeast.

Ethyl carbamate (EC) is a naturally occurring substance in alcoholic beverages from the reaction of ethanol with urea during fermentation and storage. EC can cause dizziness and vomiting when consumed in small quantities and develop kidney cancer when consumed in excess. Thus, the reduction of EC formation in alcoholic beverages is important for food safety and human health.

Gut microbiota modulation and gold nanoparticle-mediated photothermal therapy for treatment of recalcitrant acne.

Recent studies highlight that gut dysbiosis, an imbalanced state of intestinal microbiota, exacerbates skin inflammation. Here, we showed the presence of gut microbiota alterations in two patients with recalcitrant acne and investigated the impact of its therapeutic modulation together with gold nanoshell-mediated photothermal therapy (gold PTT).

Black Si Photocathode with a Conformal and Amorphous MoS Catalytic Layer Grown Using Atomic Layer Deposition for Photoelectrochemical Hydrogen Evolution.

We demonstrated how the photoelectrochemical (PEC) performance was enhanced by conformal deposition of an amorphous molybdenum sulfide (a-MoS) thin film on a nanostructured surface of black Si using atomic layer deposition (ALD). The a-MoS is found to predominantly consist of an octahedral structure (S-deficient metallic phase) that exhibits high electrocatalytic activity for the hydrogen evolution reaction with a Tafel slope of 41 mV/dec in an acid electrolyte. The a-MoS has a smaller work function (4.

The Effect of a Non-Invasive Positive Pressure Ventilation Simulation Program on General Ward Nurses' Knowledge and Self-Efficacy.

The purpose of this study is to develop a simulation-based ventilator training program for general ward nurses and identify its effects. Quantitative data were collected from 29 nurses (intervention group: 15, control group: 14), of which seven were interviewed with focus groups to collect qualitative data. The quantitative results revealed significant differences in ventilator-related knowledge ( = 0.

Safety of Combined Fractional Microneedle Radiofrequency and CO2 as an Early Intervention for Inflammatory Acne and Scarring Treated With Concomitant Isotretinoin.

Background: Fractional microneedle radiofrequency (FMRF) systems are popular options for treating acne scars. However, treatment efficacy when used in combination with traditional ablative fractional laser (AFL) and the safety profile with concomitant use of isotretinoin remain unknown.

Objective: The aim of this study was to assess the safety and efficacy of an early intervention combination treatment protocol for inflammatory acne and acne scars.

Bipolar Energetics and Bifunctional Catalytic Activity of a Nanocrystalline Ru Thin-Film Enable High-Performance Photoelectrochemical Water Reduction and Oxidation.

Photoelectrochemical (PEC) cells, which represent a promising technology for the production of hydrogen fuel through water splitting reactions, must meet two criteria to achieve high-performance operation: (i) a high thermodynamic open-circuit potential and (ii) a low kinetic overpotential. Herein, we achieved these criteria in both an oxygen-evolving n-Si photoanode and hydrogen-evolving p-Si photocathode by simple electrodeposition of a nanocrystalline thin film of Ru. The bifunctional electrocatalytic activity of the nanocrystalline Ru led to low overpotentials in both the acidic oxygen evolution reaction (0.

Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation.

Background: Extrinsic skin aging caused by atmospheric pollutants is associated with a sustained inflammatory response which is a significant risk factor for lentigines and melasma.

Aims: The aim of this study was to evaluate the efficacy of topical application of combination formulation of vitamin C, vitamin E, and ferulic acid as an adjuvant to Q-switched Nd:YAG (QSNY) lasers treatment in individuals with lentigines and melasma.

Methods: A single blinded, prospective, randomized split-face trial was conducted.

Nitramine-Group-Containing Energetic Prepolymer: Synthesis, and Its Properties as a Binder for Propellant.

A composite solid propellant which generates high propulsive force in a short time is typically composed of an oxidizer, a metal fuel powder and a binder. Among these, the binder is an important component. The binder maintains the mechanical properties of propellant grains and endures several thermal and mechanical stresses in the engine.

A semiconductor junction photoelectrochemical device without a depletion region.

Semiconductor junctions are believed to form a depletion region at the band edge of the semiconductor as the chemical potentials for electrons (work functions) are aligned to the same level. Here, we demonstrated that ultrathin Ni film (less than 4 nm thick)/Si junction-based photoelectrochemical (PEC) devices have no depletion region due to three distinct phenomena: (i) the electrostatic or electrochemical potential extrinsically charged to the electrolytic-capacitive Ni surface dominates rather than the chemical potential of electrons (work function) of the bulk Ni, (ii) the charged potential is dynamically variable depending on the reaction and is rapidly volatile so as not to be constant; therefore, (iii) the charged potential is misaligned with the chemical potential of Si under equivalent circuit conditions. Such junction PEC devices were shown to follow a novel operating principle in which the output voltage (open circuit potential) is generated by the electrochemical potential charged at the Ni surface, and not by the light-induced potential (photovoltage) in Si.

Seasonal differences in dissolved organic matter properties and sources in an Arctic fjord: Implications for future conditions.

The Arctic Ocean is undergoing drastic changes due to the effects of climate change. Arctic fjords are preferred systems to study these changes as they respond quickly to variations in ocean, land and atmosphere conditions. In this study, we investigated for the first time the seasonal variability of dissolved organic matter (DOM) properties and its origin in an Arctic fjord, which allows for an assessment of the future potential effects of climate change in this environment.

Seebeck-voltage-triggered self-biased photoelectrochemical water splitting using HfO/SiO bi-layer protected Si photocathodes.

The use of a photoelectrochemical device is an efficient method of converting solar energy into hydrogen fuel via water splitting reactions. One of the best photoelectrode materials is Si, which absorbs a broad wavelength range of incident light and produces a high photocurrent level (~44 mA·cm). However, the maximum photovoltage that can be generated in single-junction Si devices (~0.

Dynamic Photoelectrochemical Device with Open-Circuit Potential Insensitive to Thermodynamic Voltage Loss.

The open-circuit potential ( V) represents the maximum thermodynamic potential in a device, and achieving a high V is crucial for self-biased photoelectrochemical (PEC) devices that use only solar energy to produce chemical energy. In general, V is limited by the photovoltage ( V), which is a potential difference generated by light-induced thermodynamic processes at semiconductor photoelectrodes, such as the generation and recombination of charge carriers. Therefore, low light intensity and nanostructured semiconductor materials degrade V (and V) by inefficient carrier generation and by enhancing recombination loss, respectively.

Hydrogen Water Drinking Exerts Antifatigue Effects in Chronic Forced Swimming Mice via Antioxidative and Anti-Inflammatory Activities.

Purpose: This study was performed to evaluate antifatigue effect of hydrogen water (HW) drinking in chronic forced exercise mice model.

Materials And Methods: Twelve-week-old C57BL6 female mice were divided into nonstressed normal control (NC) group and stressed group: (purified water/PW-treated group and HW-treated group). Stressed groups were supplied with PW and HW, respectively, ad libitum and forced to swim for the stress induction every day for 4 consecutive weeks.

Dynamic Photoelectrochemical Device Using an Electrolyte-Permeable NiO /SiO/Si Photocathode with an Open-Circuit Potential of 0.75 V.

As a thermodynamic driving force obtained from sunlight, the open-circuit potential (OCP) in photoelectrochemical cells is typically limited by the photovoltage ( V). In this work, we establish that the OCP can exceed the value of V when an electrolyte-permeable NiO thin film is employed as an electrocatalyst in a Si photocathode. The built-in potential developed at the NiO /Si junction is adjusted in situ according to the progress of the NiO hydration for the hydrogen evolution reaction (HER).

Endogenous Agmatine Induced by Ischemic Preconditioning Regulates Ischemic Tolerance Following Cerebral Ischemia.

Ischemic preconditioning (IP) is one of the most important endogenous mechanisms that protect the cells against ischemia-reperfusion (I/R) injury. However, the exact molecular mechanisms remain unclear. In this study, we showed that changes in the level of agmatine were correlated with ischemic tolerance.

Facile Synthesis of F-TiO2/TiOF2 Mixture by High-Thermal Direct Fluorination and Its Photocatalytic Evaluation.

In this study, the mixture of F-TiO2/TiOF2 has been easily synthesized using titanium (IV) isopropoxide (TTIP) as titanium source by direct fluorination at high temperature according to different partial pressure of fluorine gas. The morphological properties and crystalline of thermally fluorinated photocatalysts were investigated using scanning electron microscope (SEM) and X-ray diffraction (XRD). Chemical composition and optical properties of thermally fluorinated photocatalysts were analyzed by X-ray Photoelectron Spectroscopy (XPS) and Photoluminescence (PL) spectrometer.

Ozonation of chlortetracycline in the aqueous phase: Degradation intermediates and pathway confirmed by NMR.

Chlortetracycline (CTC) degradation mechanism in aqueous phase ozonation was evaluated for degradation mechanism and its correlation with the biodegradability and mineralization. CTC was removed within 8 and 4 min of ozonation at pH 2.2 and 7.

Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea.

Purpose: The purpose of this study was to assess the safety and early outcomes of the Pipeline device for large/giant or fusiform aneurysms.

Materials And Methods: The Pipeline was implanted in a total of 45 patients (mean age, 58 years; M:F=10:35) with 47 large/giant or fusiform aneurysms. We retrospectively evaluated the characteristics of the treated aneurysms, the periprocedural events, morbidity and mortality, and the early outcomes after Pipeline implantation.

Evaluation of orange peel for biosurfactant production by Bacillus licheniformis and their ability to degrade naphthalene and crude oil.

A Gram-positive bacterium was isolated from mangrove soil and was identified as Bacillus licheniformis (KC710973). The potential of a mangrove microorganism to utilize different natural waste carbon substrates for biosurfactant production and biodegradation of hydrocarbons was evaluated. Among several substrates used in the present study, orange peel was found to be best substrate of biosurfactant yield with 1.

Folding-Generated Molecular Tubes Containing One-Dimensional Water Chains.

A series of indolocarbazole-pyridine (IP) oligomers were prepared that fold into helical conformations, and their folding features in solution and in the solid state were revealed. Helical folding of these IP foldamers is induced by dipolar interactions through the ethynyl bond and π-stacking between two repeating units. Upon helical folding, (1)H NMR signals of aromatic protons were significantly shifted upfield by Δδ = 0.

Design of a fused phantom for quantitative evaluation of brain metabolites and enhanced quality assurance testing for magnetic resonance imaging and spectroscopy.

Background: Magnetic resonance imaging and spectroscopy (MRI-MRS) is a useful tool for the identification and evaluation of chemical changes in anatomical regions. Quality assurance (QA) is performed in either images or spectra using QA phantom. Therefore, consistent and uniform technical MRI-MRS QA is crucial.

Bio-inspired bending actuator for controlling conical nose shape using piezoelectric patches.

In this paper, a bio-inspired bending actuator was designed and fabricated using piezoelectric patches and cantilever-shaped beam for controlling nose shape. The aim of this study is to investigate the use of the bending actuator. PZT and single crystal PMN-PT actuators were used to generate translational strain and shear stress.