Publications by authors named "Jin-Yong Xu"

Background: Older age is a risk factor for obstructive sleep apnea (OSA), which is associated with the development of nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the correlation between OSA and liver injury among older patients. .

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Article Synopsis
  • Patients with obstructive sleep apnoea (OSA) face significant damage to their blood vessels, primarily due to a condition called chronic intermittent hypoxia (CIH).
  • The study examined how CIH impacts human vein endothelial cells by monitoring cell health, mitochondrial function, and specific protein expressions.
  • Findings revealed that CIH led to decreased cell viability and increased cell death, but treatments with certain drugs improved cell survival and mitochondrial health, indicating that a protein called PPARγ plays a critical role in these protective processes.
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A series of cationic cyclometalated iridium(III) complexes with -carborane cage on the main ligand of 2-phenylbenzothiazole were synthesized. The prepared iridium complexes (-) were fully characterized by UV-vis, NMR, and FT-IR spectra. The exact molecular structure of complex was further studied by single crystal X-ray diffraction analysis.

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Background: Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in China, constitutes a Public Health Emergency of International Concern. It is well known that COVID-19 patients may have increased serum lactate dehydrogenase (LDH) levels in the early stage. The clinical changes in LDH may have predictive value in disease evolution and prognosis in critically ill COVID-19 patients.

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Introduction: Small fiber neuropathy (SFN)-the early stage of diabetic peripheral neuropathy (DPN)-progresses gradually and is difficult to diagnose using neurophysiological tests. To facilitate the early diagnosis of SFN, biomarkers for SFN must be identified. The purpose of this study was to investigate the characteristics of SFN in prediabetic patients and the relationship between pNF-H and SFN.

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