Publications by authors named "Jin-Ying Lin"

Article Synopsis
  • Rapidly progressive interstitial lung disease (RP-ILD) is a serious complication in patients with idiopathic inflammatory myopathy (IIM), often leading to poor outcomes, making the need for effective treatments essential.
  • Plasma exchange (PE) may help by quickly removing harmful substances from the blood, and this study assesses its effectiveness when combined with immunosuppressants in improving survival rates and reducing inflammatory markers.
  • Results showed an 80% survival rate at 6 months for patients undergoing PE, which was significantly better than for those not receiving PE, suggesting its potential as a beneficial treatment option for IIM-RP-ILD.
View Article and Find Full Text PDF
Article Synopsis
  • Scientists wanted to see if combining arsenic compounds with a medicine called imatinib could help people with chronic myeloid leukemia (CML) better than just using imatinib alone.
  • They did a study with 191 patients who were recently diagnosed, giving some a mix of arsenic and imatinib while others got a placebo with imatinib.
  • After following the patients for over four years, they found that while both treatments worked similarly, the combination treatment might help more people achieve better results after 12 months.
View Article and Find Full Text PDF

Objective: To show the impact of Sjögren's syndrome (SS) on maternal and fetal outcomes following pregnancy.

Methods: We performed a literature search based on PubMed, Web of science, Wan fang, China National Knowledge Infrastructure and ProQuest databases from 1 January 2007 to 6 November 2022. Grading of Recommendations, Assessment, Development, and Evaluations approach was used to assess the certainty of the evidence.

View Article and Find Full Text PDF

Background: Rheumatic diseases, mainly affecting women, including rheumatoid arthritis, Sjogren's syndrome, systemic lupus erythematosus, etc., are chronic, inflammatory, autoimmune disorders that may involve multiple organs or systems and are closely related to sexual health, which is an important aspect of human physical and mental health. Sjogren's syndrome (SS) is the second most common rheumatic illnesses after rheumatoid arthritis with a female predominance.

View Article and Find Full Text PDF

Background: The optimal treatment strategy for refractory or relapse (R/R) indolent non-Hodgkin lymphoma (iNHL) has not been fully identified. This study aims to investigate the efficacy and tolerance of bendamustine hydrochloride developed in native Chinese corporation in the treatment of patients with R/R iNHL.

Methods: A total of 101 patients from 19 centers were enrolled in this study from July 2016 to February 2019.

View Article and Find Full Text PDF

In an attempt to establish the advantages of fluorescence in situ hybridization (FISH) studies over conventional cytogenetic (CC) analysis, a total of 2302 de novo MDS patients from 31 Chinese institutions were prospectively selected in the present study for both CC and standardized FISH analysis for +8, -7/7q-, -5/5q-, 20q- and-Y chromosomal abnormalities. CC analysis was successful in 94.0% of the patients; of these patients, 35.

View Article and Find Full Text PDF

The aim of this study is to investigate the remission rate of rheumatoid arthritis (RA) in China and identify its potential determinants. A multi-center cross-sectional study was conducted from July 2009 to January 2012. Data were collected by face-to-face interviews of the rheumatology outpatients in 28 tertiary hospitals in China.

View Article and Find Full Text PDF

Objective: To investigate the medication status of rheumatoid arthritis (RA) patients and to analyze the clinical use of sulphasalazine (SSZ) and the adverse effect.

Methods: A total of 1 096 outpatients and inpatients diagnosed with RA were investigated in 21 hospitals all over China from July 2009 to December 2010, including gender, age of onset, clinical manifestations, as well as the clinical characteristics and medication status of 160 RA patients who received SSZ therapy.

Results: In the group of 160 patients who received SSZ, the male-to-female ratio was 1:7, The average age at onset was (46.

View Article and Find Full Text PDF

Objective: To learn about the prevalence and risk factors of coronary artery disease (CAD) in rheumatoid arthritis (RA).

Methods: Data were obtained from a 12-month retrospective investigation of the patients with RA, randomly selected from Departments of Rheumatology and Immunology in 21 big hospitals in China. The data were collected about their social conditions, clinical conditions, medications associated with RA, such as disease modifying anti-rheumatic drugs (DMARDs), non steroidal anti-inflammatory drugs (NSAIDs), glucocorticoid, biologic agents.

View Article and Find Full Text PDF

This study was aimed to investigate the clinical value of detecting BCR/ABL fusion gene by fluorescence in situ hybridization (FISH). The conventional cytogenetic test and detection of BCR/ABL fusion gene by FISH for bone marrow of patients with newly diagnosed chronic myeloproliferative disease or myelodysplastic and myeloproliferative disorders, acute lymphocytic leukemia and chronic myelogenous leukemia (CML) after allogeneic hematopoietic stem cell transplantation were carried out. The results showed that (1) out of 46 newly diagnosed as chronic myeloproliferative disease or myelodysplastic and myeloproliferative disorders, 22 cases were diagnosed as CML, the FISH detection showed all positive (100%), while cytogenetic test showed 86.

View Article and Find Full Text PDF

Objective: The aim of this investigation was to examine the changes of the color stability, surface microstructure and chemical constitution of light-curing composite resin after accelerated aging, and the relations between them.

Methods: Four light-curing composite resin were aged in an accelerated aging instrument. The color was measured by CIE L*a*b* with a spectrophotometer after treatment for 24 h and 96 h.

View Article and Find Full Text PDF

This study was purpose to explore the effect of combination of SCF, FL, TPO without serum and stroma on the ex vivo expansion of the mononuclear cells derived from umbilical cord blood (CB) and to evaluate the proper infused time and implantation of expanded cells. Mononuclear cells derived from CB were cultured with the combination of SCF, FL and TPO for 14 days. At 0, 7, 10 and 14 days, the total mononuclear cells in culture were counted, CD34+ cells and CD34+CXCR4+, CD34+CD49d+ cells were assayed by flow cytometry, and CFU were determined.

View Article and Find Full Text PDF

Objective: To evaluate the matching of the shade between beverage and modifying porcelain shade guide according to Munsell color order system, thus to provide the reference basis for selecting modifying porcelain to mimic the stain of natural tooth by technician.

Methods: The shade of Vita Akzent, Vita Interno, Shofu Vintage & Unibond and Noritake Super Porcelain EX-3 shade tabs as well as 15 kinds of beverage were measured according to Munsell color order system on Color-Eye 7000A spectrophotometer. The difference of the frequency of approximate hue, value, and chroma between shade tabs and beverage were compared by calculating the Fisher exact probabilities.

View Article and Find Full Text PDF

To simultaneously compare and evaluate the examinations of bone marrow smear and trephine biopsy in differential diagnosis and therapeutical effect of pancytopenia patients, the differences between bone marrow smear and trephine biopsy in degree of cellularity, misdiagnosis rate and therapeutical effect for 71 patients with pancytopenia were analyzed. The results showed that the degree of cellularity in bone marrow biopsy for cytologic morphology was higher than that from the smear, but misdiagnosis rate in the biopsy was lower than that in the smear. In conclusion, bone marrow biopsy is necessary to the differential diagnosis and more valuable for evaluation of therapeutical effect and prognosis of pancytopenia patients.

View Article and Find Full Text PDF