Publications by authors named "Jin-Xu Zhang"
Intervention of inflammation associated with ankylosing spondylitis by triptolide promotes histone H3 Iys-27 trimethylation.
Immunopharmacol Immunotoxicol
December 2024
This study aims to explore the effects of Triptolide (TP) on the differentiation of Th17 cells in ankylosing spondylitis (AS). Peripheral blood mononuclear cells (PBMCs) collected from 10 patients with active AS patients were exposed to TP, GSK-J4 or vehicle. T lymphocyte subsets were analyzed using flow cytometry.
View Article and Find Full Text PDFThe JASMONATE ZIM DOMAIN (JAZ) proteins are a key inhibitors of the jasmonic acid (JA) signaling pathway that play an important role in the regulation of plant growth and development and environmental stress responses. However, there is no systematic identification and functional analysis of JAZ gene family members in sugarcane. In this study, a total of 49 SsJAZ genes were identified from the wild sugarcane species Saccharum spontaneum genome that were unevenly distributed on 13 chromosomes.
View Article and Find Full Text PDFArticle Synopsis
- The bromodomain binds to acetylated lysine residues in histones, which activates gene transcription; the study characterizes 37 GTE and GTE-Like genes in sugarcane (Saccharum spontaneum) for the first time.
- SsGTEL3a, a specific gene identified, showed higher expression under drought stress in drought-resistant sugarcane varieties and improved drought tolerance when overexpressed in Arabidopsis.
- The study also uncovered an interaction between the gene ScFAR1 and SsGTEL3a, highlighting new potential targets for molecular breeding aimed at enhancing drought resistance in sugarcane.