Publications by authors named "Jin-Xin Xie"

The purpose of this study was to investigate the effect of Huaier extract supernatant(HES) on the proliferation, apoptosis, autophagy, and migration of human gastric cancer HGC-27 and MGC-803 cells and its molecular mechanisms. The main components in HES were preliminarily analyzed by high-performance liquid chromatography-mass spectrometry(HPLC-MS). Methyl thiazolyl tetrazolium(MTT) assay, colony formation assay, and 5-ethynyl-2'-deoxyuridine(EdU) staining assay were used to explore the effect of HES on the proliferation of human gastric cancer HGC-27 and MGC-803 cells.

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Article Synopsis
  • The study aimed to investigate human parechovirus (HPeV) in stool samples from children under 5 with acute gastroenteritis.
  • A real-time PCR test identified HPeV in 27 out of 306 children, with a higher incidence in autumn and a notable peak in July, especially in children older than 2.
  • The findings align with previous reports on HPeV epidemiology, and the researchers emphasize the importance of ongoing large-scale surveillance for HPeV, as HPeV3 was notably absent in their samples.
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Group A rotavirus are the most frequently detected viral agent associated with the acute diarrhea in calves. In order to investigate the situation of rotavirus strains circulating in diary farms, a total of 117 fecal specimens were collected from diarrhea calves under 4 weeks-age on Yinluo diary farm in Daqing region in China from 2008 to 2009. Ten specimens were detected to be positive by a Rotavirus Group A Diagnostic Kit, which confirmed that the rotavirus was important viral agent associated with diarrhea in this diary farm.

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Article Synopsis
  • The study aimed to identify and analyze the Aichi virus in both diarrhea cases and healthy children in Lanzhou, exploring its potential link to infant diarrhea.
  • Utilizing RT-PCR methods, researchers found a very low detection rate of Aichi virus (0.06%) in hospitalized children with diarrhea, with no virus found in healthy children; the virus detected belonged to genotype B.
  • The findings indicate the presence of B genotype Aichi virus in China, highlighting the need for further research on its characteristics and role in illness.
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Objective: To study the epidemiologic characteristics of virus-induced acute diarrhea in children under 5 years old in Taiyuan, Shanxi province.

Methods: Stool specimens and clinical data were collected from 346 inpatients with acute diarrhea from children less than 5 years old. Rotavirus-positive specimens were identified by ELASA kit.

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From November 2008 to January 2009, a sharp increase of diarrhea in children in Guangdong province appeared, we randomly collected 53 stool specimens from out-patient children with dirrhea in 3 major hospitals (Guangzhou City Children's Hospital, Shenzhen Baoan District Maternal and Child Health Hospital, First Affiliated Hospital of Shantou University). Rotavirus and calicivirus were screened by ELISA and RT-PCR. We found 29 cases of rotavirus infection with diverse serotypes.

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