Publications by authors named "Jin-Xi He"
Article Synopsis
- Thymoma is the most common tumor found in the front part of the chest, and this study focused on identifying prognostic factors for patients who underwent surgery to remove the tumor.
- The research involved 137 patients and tracked their recovery, determining that 5-year progression-free survival (PFS) was 79.5% and overall survival (OS) was 88.4%.
- Key findings indicated that smoking and tumor size impact PFS, while high neutrophil levels are crucial for determining OS; a nomogram was created to help predict patient outcomes based on these factors.
Background: Recent studies have shown that according to the expression levels of achaete-scute homolog 1 (ASCL1), neurogenic differentiation factor 1 (NEUROD1), and POU class 2 homeobox 3 (POU2F3), small cell lung cancer (SCLC) can be divided into four subtypes: SCLC-A (ASCL1-dominant), SCLC-N (NEUROD1-dominant), SCLC-P (POU2F3-dominant), and SCLC-I (triple negative or SCLC-inflamed). However, there are limited data on the clinical characteristics and prognosis of molecular subtypes of SCLC.
Methods: Immunohistochemistry (IHC) was used to detect the expression levels of ASCL1, NEUROD1, and POU2F3 in 53 patient samples of resectable SCLC.
We aimed to evaluate the role of pretreatment carcinoembryonic antigen (CEA) and platelet to lymphocyte ratio (PLR) in predicting brain metastasis after radical surgery for lung adenocarcinoma patients. The records of 103 patients with completely resected lung adenocarcinoma between 2013 and 2014 were reviewed. Clinicopathologic characteristics of these patients were assessed in the Cox proportional hazards regression model.
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