Publications by authors named "Jin-Woo Bae"

We isolated three novel strains, S1, S2, and S5, from human oral cavities and identified them as distinct novel species. All these strains are facultatively anaerobic, Gram-stain-positive, and non-flagellated bacteria. Their optimal growth conditions for these strains were observed in Columbia broth (CB) at 37 °C, pH 7.

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Coupling piezo-active and triboelectric materials has recently emerged as an effective technique for developing high-performance hybrid nanogenerators (HNGs). This is the first paper to report the fabrication of piezo-active poly(vinylidene fluoride-hexafluoropropylene)(PVDF-HFP)/MXene-based hybrid composite fibers through conventional electrospinning. Here, the effect of MXene content (1-5%) on the surface potential and electrical performance of the as-synthesized composites is investigated and optimized.

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Background And Purpose:  We aimed to examine the histological characteristics of vastus lateralis muscles in patients undergoing total hip arthroplasty (THA) following femoral neck fractures and to explore the correlation between muscle fiber types and postoperative functional recovery.

Methods:  34 patients undergoing THA for femoral neck fractures were included. A biopsy of the vastus lateralis muscle was performed during surgery, followed by immunohistochemical staining.

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Article Synopsis
  • * IBD patients, especially those with Crohn's disease, showed lower microbial diversity compared to healthy individuals, with a notable increase in the Escherichia-Shigella genus related to dysbiosis.
  • * The study found that specific microbial taxa could help in diagnosing IBD and that functional pathways linked to bacterial pathogenesis were upregulated, indicating potential areas for future clinical research on IBD management.
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  • - The gut microbiome is a diverse collection of microorganisms in the human intestine that plays a crucial role in overall health, with imbalances linked to various health issues like gastrointestinal and metabolic disorders.
  • - Fecal microbiota transplantation (FMT) and live biotherapeutic products (LBPs) are promising treatments aimed at restoring gut microbial balance and addressing related health problems.
  • - The review emphasizes the importance of standardization, safety, and long-term studies to improve the clinical use of FMT and LBPs for better health outcomes.
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Existing research has underscored the vital interplay between host organisms and their associated microbiomes, which affects health and function. In both plants and animals, host factors critically shape microbial communities and influence growth, health, and immunity. Post-harvest plants, such as those used in kimchi, a traditional Korean dish, offer a unique avenue for exploring host-microbe dynamics during fermentation.

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Background: Lipid-lowering therapies are mainstays in reducing recurrence after acute ischemic stroke (AIS). Evolocumab, a Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitor, is a promising lipid-lowering agent known to decrease LDL cholesterol and mitigate vascular events alongside statins. However, its effects on the early functional outcomes post-mechanical thrombectomy (MT) remain unclear.

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Endovascular thrombectomy (EVT) has been established as the standard of care in the treatment of acute ischemic stroke (AIS) based on landmark randomized controlled trials. Nevertheless, while the strict eligibility of EVT for AIS patients restrict the wide application of EVT, a considerable population still undergoes off-label EVT. Besides, it is important to acknowledge that recanalization is not achieved in approximately 20% of procedures, and more than 50% of patients who undergo EVT still do not experience a favorable outcome.

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There are many disagreements about the merits of navigation in total knee arthroplasty (TKA). We compared and analyzed the difference in the accuracy of femoral resection according to the degree of lateral femoral bowing in 2 surgical methods (conventional and navigation-assisted TKA). A total of 238 (100 who underwent navigation TKA and 138 who underwent conventional TKA from 2016 to 2021) were included in this study.

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Background: The objectives of the researchers are as follows: First, to investigate whether intraoperative or postoperative administration of Intravenous (IV) iron supplements in patients undergoing primary total knee arthroplasty (TKA) can contribute to the hemoglobin recovery during the postoperative period (between 4 and 8 weeks after surgery). Second, to examine whether the administration of IV iron supplements during or immediately after TKA in patients undergoing primary TKA can reduce the need for allogenic blood transfusion during hospitalization.

Methods: Articles published between January 1, 1990, and June 30, 2023 were searched in PubMed, Cochrane, and Embase.

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First, we want to find out whether computer-assisted surgery (CAS) for total knee arthroplasty (TKA), which does not require opening the femoral medullary canal, results in a lesser C-reactive protein (CRP) level increase postoperatively compared to manual TKA. Second, they seek to examine whether the CRP reduction in CAS TKA and manual TKA follows a similar pattern within the first 2 weeks after surgery. Third, the study aims to compare and analyze the CRP levels in 3 different groups: CRP levels in CAS TKA with surgeons who started TKA surgery by CAS, CRP levels in manual TKA by surgeons with little experience, and CRP levels in skillful manual TKA performed after conducting over 200 cases.

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Background: Ultramicrobacteria (UMB), also known as ultra-small bacteria, are tiny bacteria with a size less than 0.1 µm. They have a high surface-to-volume ratio and are found in various ecosystems, including the human body.

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Objective: Little is known about the relationship between postoperative changes in cerebral perfusion and the ivy sign representing leptomeningeal collateral burden in moyamoya disease (MMD). This study aimed to investigate the usefulness of the ivy sign in evaluating cerebral perfusion status following bypass surgery in patients with adult MMD.

Methods: Two hundred thirty-three hemispheres in 192 patients with adult MMD undergoing combined bypass between 2010 and 2018 were retrospectively enrolled.

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Three novel bacterial strains, 321, 335, and 353, were isolated from the intestines of Aegosoma sinicum larvae collected from Paju-Si, South Korea. The strains were Gram-negative, obligate aerobe and had rod-shaped cells with a single flagellum. The three strains belonged to the genus Luteibacter in the family Rhodanobacteraceae and shared < 99.

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Objective: Several particular morphological factors that contribute to the hemodynamics of the anterior communicating artery (ACoA) have been documented, but no study has investigated the role of the degree of anterior cerebral artery (ACA) rotation on the presence of ACoA aneurysms (ACoAAs).

Methods: A retrospective study of an institutional aneurysm database was performed; patients with ruptured or nonruptured ACoAAs were selected. Two sex- and age-matched control groups were identified: control Group A (nonaneurysms) and control Group B (middle cerebral artery aneurysms).

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Background: Reconstructive strategies for unruptured vertebral artery dissecting aneurysms (VADAs) have increasingly relied on newly developed endovascular devices. However, their clinical performance metrics are seldom reported.

Objective: To compare stent-assisted coil embolization (SACE) and flow-diverting stent (FDS) deployment as treatments for unruptured VADAs, focusing on efficacy and safety.

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Article Synopsis
  • Two new bacterial strains, J2M5 and J1M15, were discovered in the intestinal tract of a lake prawn, characterized by their distinct colony colors and aerobic properties.
  • Strain J2M5 is an obligately aerobic rod-coccus bacterium with a genome size of 4.52 Mbp, while strain J1M15 is a facultative aerobe with a genome size of 3.20 Mbp, both showing high genetic similarity to known strains.
  • Comprehensive analysis revealed differences in their cellular structure, fatty acids, and potential for antibiotic resistance, suggesting they are novel species within their respective genera.
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  • - The study explored how the gut microbiome might affect cancer development, specifically looking at newly diagnosed patients with diffuse large B-cell lymphoma (DLBCL), finding significant differences in microbial composition compared to healthy individuals.
  • - Patients with DLBCL showed lower microbial diversity and higher levels of the Enterobacteriaceae family, which were linked to worse treatment outcomes, including shorter progression-free survival.
  • - The presence of Enterobacteriaceae was associated with complications like febrile neutropenia and had connections to specific cytokine levels, highlighting the need for further research on gut dysbiosis in lymphoma patients.
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Purpose: Stent protective or balloon remodeling techniques have enabled coil embolization of complexly configured aneurysms. Still, the utility of such methods may be limited in some small-caliber and/or inherently tortuous lesions. The present study was conducted to examine the efficacy of microcatheter protection (MCP) when applied in these circumstances.

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Presently, pertinent information on the ultra-small microbiome (USM) in fermented vegetables is still lacking. This study analyzed the metatranscriptome and metataxonome for the USM of kimchi. Tangential flow filtration was used to obtain a USM with a size of 0.

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Three novel strains, (D17, D13, and D25) isolated from the gut of the Korean dark sleeper (Odontobutis platycephala), Kumgang fat minnow (Rhynchocypris kumgangensis), and the Korean oily bitterling (Tanakia koreensis) were identified as two novel species. Strains D17 and D13 showed the highest similarities in 16S rRNA gene and complete genome sequences to Deefgea rivuli WB 3.4-79 (98.

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Cardiovascular disease (CVD) is a health problem worldwide, and elevated cholesterol levels are a key risk factor for the disease. Dysbiotic gut microbiota has been shown to be associated with CVD development. However, the beneficial effects of healthy microbiota in decreasing cholesterol levels have not been summarized.

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Synopsis of recent research by authors named "Jin-Woo Bae"

  • - Jin-Woo Bae's recent research encompasses various fields, including biomedical engineering, orthopedics, and gastrointestinal health, reflecting a diverse exploration of innovative solutions for health-related challenges.
  • - One significant area of focus is the development of advanced hybrid nanogenerators using electrospun composites, showcasing the interplay between materials science and energy generation, highlighting the potential of MXene and PVDF-HFP in enhancing nanogenerator performance.
  • - In the medical field, Bae investigates the relationship between muscle histology and functional recovery after hip surgeries, the impacts of the gut microbiome on inflammatory bowel disease, and gastrointestinal health, and explores methodologies for improving outcomes in total knee arthroplasty and acute ischemic stroke treatments.