Publications by authors named "Jin-Wei Ying"
Background: Intervertebral disc (IVD) degeneration is a condition characterized by a reduction in the water and extracellular matrix content of the nucleus pulposus (NP) and is considered as one of the dominating contributing factors to low back pain. Recent evidence suggests that stromal cell-derived factor 1α (SDF-1α) and its receptor C-X-C chemokine receptor type 4 (CXCR4) direct the migration of stem cells associated with injury repair in different musculoskeletal tissues.
Aim: To investigate the effects of SDF-1α on recruitment and chondrogenic differentiation of nucleus pulposus-derived stem cells (NPSCs).
Objective: Angiographic slow/no-reflow during emergency percutaneous coronary intervention (PCI) in patients with ST-elevated acute myocardial infarction (AMI) may result in unfavorable outcomes. The aim of our study was to investigate the clinical factors and angiographic findings that predict slow/no-reflow phenomenon and the long-term prognosis of AMI patients with angiographic slow/no-reflow.
Methods: A total of 210 consecutive AMI patients, who underwent primary PCI within 12 hours of symptom onset were divided into a normal flow group (thrombolysis in myocardial infarction [TIMI] flow grade 3, n = 169) and a slow/no-reflow group (≤TIMI flow grade 2, n = 41), based on cineangiograms performed during PCI.
Background: Inflammatory mechanisms had played an important role in the occurrence and prognosis of acute myocardial infarction, inflammatory mediators was associated with adverse outcomes of acute myocardial infarction. This study tested the hypothesis that in the acute phase of myocardial infarction with ST-segment elevation, neutrophil count and high-sensitivity C-reactive protein are predictive of angiographic morphologic features that indicate thrombus formation in the infarct-related artery.
Methods: This retrospective study included 182 consecutive patients with acute myocardial infarction and ST-segment elevation.
Objective: Distal embolization after percutaneous coronary intervention (PCI) is one of the major mechanisms of no-reflow. The aim of the study was to investigate clinical, angiographic predictors of distal embolization on angiography in patients with ST-elevation acute myocardial infarction (AMI) after PCI, and to assess the short-term prognosis of patients with distal embolization.
Methods: There were 318 consecutive AMI patients, who underwent primary PCI within 12 h of symptom onset, and were divided into distal embolization group (N = 97) and non-distal embolization group (N = 221), based on cineangiograms performed during PCI.