Synopsis of recent research by authors named "Jin-Sang Wang"
- Jin-Sang Wang's research primarily focuses on the molecular mechanisms involved in cancer progression and treatment, particularly in gastric and hepatocellular carcinomas, showcasing the roles of various proteins and inhibitors in these processes.
- Key findings include the development of monoclonal antibodies targeting autocrine motility factor (AMF) to suppress gastric cancer growth and the investigation of gankyrin's involvement in cell proliferation and p53 degradation in hepatocellular carcinoma models.
- Additionally, the work explores the impact of HCV core protein on liver fibrogenesis, utilizing innovative in vitro co-culture systems to elucidate the interactions between viral proteins and hepatic stellate cells, which may contribute to liver cirrhosis.
