Exercise training improves cardiac function and regulates myocardial mitophagy differently in ischaemic and pressure-overload heart failure mice.

New Findings: What is the central question of this study? What are the cardioprotective effects of different aerobic exercises on chronic heart failure with different aetiologies, and is mitophagy involved? What is the main finding and its importance? Moderate-intensity continuous training may be the 'optimum' modality for improving cardiac structure and function in ischaemic heart failure, while both moderate-intensity continuous training and high-intensity interval training were suitable for pressure-overload heart failure. Various mitophagy pathways, especially parkin-dependent pathways, participated in the protective effects of exercise on heart failure.

Abstract: The cardioprotective effects of different aerobic exercises on chronic heart failure with different aetiologies and whether mitophagy is involved remain elusive.

Crushed/chewed administration of potent P2Y inhibitors in ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: Systematic review and meta-analysis.

Crushed or chewed potent P2Y inhibitors are commonly used in the hope of bridging the gap of platelet inhibition in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). The study aimed to investigate the efficacy and safety of this alternative oral administration strategy by performing a meta-analysis of available randomized clinical trials (RCTs). PubMed, Embase, the Cochrane Library and Web of Science medical literature databases were searched for RCTs comparing crushed/chewed vs.

[Effects of the volatiles from different tomato varieties on host selection behavior of B-biotype Bemisia tabaci].

By the methods of headspace solid-phase micro extraction and gas chromatography-mass spectrometry, and using Y-type olfactometer, this paper identified the volatiles from six tomato varieties (Zheza 809, Zheza 203, Hezuo 903, Kate No. 1, Huangtuoyan, and Jinfei), and bio-assayed the olfactory responses of female B-biotype Bemisia tabaci to the tomato plants and their released volatiles. Thirteen kinds of compounds in the volatiles collected from the six tomato varieties were identified, among which, terpenoids were the main components.