Publications by authors named "Jin-Ru Xie"
Background: Oral microbiome has been associated with various cancers, including nasopharyngeal carcinoma (NPC), but its role in cancer treatment and prognosis remains largely unknown. This study aims to address the dynamic changes in oral microbiome following cancer treatment and their prognostic implications in NPC patients.
Patients And Methods: Unstimulated whole saliva samples were collected from 23 NPC patients before and after treatment, with an average of 2.
Article Synopsis
- The study explores the link between oral microbes and their potential role in developing nasopharyngeal carcinoma (NPC), revealing that these microbes can migrate from the mouth to the nasopharynx.
- It found an increased risk of NPC associated with oral-to-nasopharyngeal microbial translocation, with certain species like Fusobacterium nucleatum identified as prevalent in NPC patients.
- Additionally, the presence of these oral microbes in tumors influences the local environment and interacts with Epstein-Barr virus (EBV) loads, suggesting a complex relationship in cancer development.
Article Synopsis
- This study explored the link between oral hygiene, the oral microbiome, and nasopharyngeal carcinoma (NPC) by analyzing 218 NPC patients and 192 healthy individuals.
- Researchers used advanced gene sequencing to evaluate the oral microbiome and found that poor oral hygiene and dental fillings were associated with a higher risk of NPC.
- The analysis suggested that changes in the oral microbiome due to poor oral hygiene could partly explain the increased risk of NPC, shedding light on the underlying mechanisms at play.
[Visualization analysis of traditional Chinese medicine for neurogenesis research based on CiteSpace].
Zhongguo Zhong Yao Za Zhi
September 2021
Article Synopsis
- The study used CiteSpace software to analyze the trends and hotspots in traditional Chinese medicine (TCM) research related to neurogenesis from 1987 to 2020, focusing on bibliometric data from the CNKI database.
- A total of 736 publications were reviewed, revealing a general upward trend in annual publications and the formation of stable research teams, primarily led by researchers such as DING Fei and ZHOU Chong-jian.
- Key areas of focus in TCM research for neurogenesis included disease treatment, therapeutic methods, and molecular mechanisms, with predictions that future research will increasingly target TCM therapies and their molecular impacts on the central nervous system.