Publications by authors named "Jin-Long Wang"
Background: Growing evidence indicates that N-methylguanosine (mG) modification plays critical roles in epigenetic regulation. However, no data regarding mG modification are currently available in Eimeria tenella, a highly virulent species causing coccidiosis in chickens.
Methods: In the present study, we explore the distribution of internal messenger RNA (mRNA) mG modification in sporulated and unsporulated oocysts of E.
Article Synopsis
- - The new mechanochromic light control technology aims to create energy-saving windows that adjust to solar irradiation but faces challenges in selective modulation for various scenarios.
- - A layer-by-layer assembly method is introduced to produce a film that responds mechanically, allowing for dynamic modulation of visible and near-infrared light, with optical modulation rates of up to 42.4% at 550 nm.
- - The multilayer structure enhances both the film's optical performance and its durability, surviving up to 100,000 stretching cycles, and demonstrates a cooling effect in real-world applications, potentially benefiting energy-efficient design.
Article Synopsis
- Thin films made from low-dimensional nanomaterials, like nanowires and nanoplates, are crucial in engineering due to their unique properties.
- The study focuses on a new method of assembling these nanostructures at a liquid interface, which improves the alignment and properties of the resulting quasi-2D nanofilms.
- Findings indicate that this new approach not only enhances electrical conductivity and optical characteristics compared to 1D materials but also opens up opportunities for better material design and synthesis techniques.
Article Synopsis
- Several trichomonad species have been found in pigs, suggesting possible health risks, but no data exists on their prevalence in Shanxi Province, North China.
- A study analyzed 362 pig fecal samples from three counties using nested PCR, revealing a 49.72% prevalence of trichomonads, with region and age significantly influencing infection rates.
- The research offers insights into the genetic similarities and variations of trichomonad isolates, contributing to the understanding of their distribution in pigs in China and helping to inform future research and control methods.
Article Synopsis
- - Developing new drugs is expensive and risky, and understanding drug-protein interactions is crucial for effective treatment, a task being revolutionized by advances in deep learning (DL).
- - Two main challenges in this area are preventing gradient disappearance while capturing detailed local characteristics and understanding the overall interactions between drugs and proteins, both of which are essential for drug development.
- - The proposed DL network, MolLoG, features two key components—a local feature encoder to extract detailed characteristics and a global interactive learning module to combine these features effectively, outperforming existing models in predicting drug-target interactions across multiple datasets.
Cerebral syphilitic gumma misdiagnosed as brain abscess: A case report.
World J Clin Cases
January 2024
Article Synopsis
- Cerebral syphilitic gumma is a rare condition often mistaken for brain tumors or abscesses due to its non-specific symptoms and similar imaging results.
- A reported case involved a patient initially misdiagnosed with a brain abscess, leading to unnecessary surgery until a correct diagnosis of syphilitic gumma was made post-operation.
- To improve diagnostic accuracy, it’s crucial for physicians to recognize the characteristics of neurosyphilis and combine multiple examination methods in their assessments.
Inhibits Ovarian Cancer Metastasis by Regulating Cytoskeleton Remodeling via .
Cancers (Basel)
December 2023
Epithelial ovarian cancer is the most lethal gynecological malignant tumor. Although debulking surgery, chemotherapy, and PARP inhibitors have greatly improved survival, the prognosis for patients with advanced EOC without HRD is still poor. , as a cell polarity factor, is involved in maintaining cell polarity and asymmetric cell division.
View Article and Find Full Text PDF. Non-primary radiation doses to normal tissues from proton therapy may be associated with an increased risk of secondary malignancies, particularly in long-term survivors. Thus, a systematic method to evaluate if the dose level of non-primary radiation meets the IEC standard requirements is needed.
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- The text discusses an innovative structural color film that can switch its color in response to external stimuli like voltage, heat, or light, enhancing display applications.
- This film features a unique design incorporating photonic crystal technology with polystyrene microspheres, which allows it to exhibit significant polarization sensitivity and broad color range based on viewing angles.
- The advancements in this intelligent film hold potential for future applications in multicolor displays and smart windows, indicating a step forward in display technology.
Article Synopsis
- Smart windows are energy-efficient innovations that adjust sunlight to improve indoor comfort and manage heat more effectively.
- Researchers developed a co-assembly strategy that combines electrochromic and thermochromic features, allowing for better control of solar radiation through tunable components.
- By optimizing the materials and structures used, the smart windows can significantly reduce near-infrared light absorption and enhance visibility while maintaining a comfortable temperature range.
Article Synopsis
- The study investigates the genotyping features of human fecal strains and the link between antibiotic resistance genes (ARGs) and multidrug resistance (MDR) in a Beijing district known for high rates of infectious diarrhea.
- Over three years, researchers isolated 94 strains from fecal samples, assessing antibiotic susceptibility and analyzing genetic data through whole-genome sequencing.
- Findings showed a high prevalence of MDR among the isolates, with similar rates in both diarrheal and healthy individuals, and the study suggests ongoing monitoring of ARGs and MDR is necessary for improving predictions and understanding the transmission of resistance genes.
[Main Infection Control Measures for Respiratory Infectious Diseases in Medical Institutions and Public Places in China].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2023
Article Synopsis
- Respiratory infectious diseases (RID) pose significant public health threats, and effective infection control (IC) is crucial for managing their spread.
- A review of literature since 2018 highlighted achievements, problems, and challenges in IC across various levels of medical institutions in China, showing inconsistent efforts in different regions.
- Recommendations include better application of existing IC tools, the development of advanced technology for new IC products, and the establishment of a digital platform for monitoring and managing infections to enhance IC measures.
Article Synopsis
- - The study examines how globalization has increased the movement of people and consequently altered the spread of diseases among foreign travelers in China, focusing on the types and characteristics of imported infections.
- - Data from 2014 to 2018 revealed that over 17,000 travelers were diagnosed with 58 different infectious diseases, with respiratory infections like influenza and blood/sex-transmitted diseases like Hepatitis B and HIV being the most common.
- - Findings highlight that Asia and Europe contribute the most cases, and Africa has the highest incidence rate. Specific seasonal patterns for vector-borne diseases were identified, indicating the need for targeted health measures.
Sepsis is a life-threatening organ dysfunction caused by the maladjustment of the body's response to infection. Abnormal immune response plays an important role in the progression of sepsis, and immunomodulatory therapy is a promising therapeutic strategy for sepsis. Great efforts have been made recently to elucidate the mechanism by which immune dysfunction contributes to sepsis, and identify potential biomarkers and targets for the diagnosis and therapy of sepsis induced by emerging pathogens, especially for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19.
View Article and Find Full Text PDFSolar thermoelectric devices play a significant role in addressing the problem of global warming, owing to their unique features of converting both waste heat and solar energy directly into electricity. Herein, a flexible 3D Janus helical ribbon architecture is designed, starting from well-aligned tellurium (Te) nanowire film, using an in situ redox process reacting with Ag and Cu resulting in n-type, p-type, and photothermal sides in one film. Remarkably, the device shows all-day electricity generation and large temperature gradient by coupling the cold side with a passive radiative cooling technique and the hot side with a selective solar absorption technique, showing a temperature gradient of 29.
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- Tellurium (Te), usually studied for positive photoconductance in p-type semiconductors, exhibits an unusual negative photoresponse in nanowires (NWs) under certain light conditions.
- The experimental results indicate that the presence of adsorbed oxygen on Te NWs influences this abnormal behavior, as it competes with the normal photoconductive effect.
- The study further investigates the impact of Te NW size and the introduction of a Te-Au heterojunction, which enhances negative photoresponse through hot-electron injection, suggesting new potential applications for Te-NW-based photodetectors.
The photothermoelectric effect, directly converting light energy into electrical energy, shows promising prospects in self-powered broad-band optical detection, which can extend to various applications, such as sensing, optoelectronic communications, and wide-temperature-range measurements. However, the low photosensitivity, narrow-band response, and rapid performance degeneration under continuous illumination restrict its broad application. Herein, we propose a simple bottom-up strategy to manipulate nanowires (NWs) into a well-defined multilayer Te-AgTe-Ag NW film, resulting in a high-performance photothermoelectric photodetector with a broad-band responsivity (4.
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- Natural biomaterials exhibit ordered nanowire structures (ONWS) that can provide unique colors and enhanced mechanical properties, with many modern nanodevices utilizing these structures for research.
- Various assembly methods, including Langmuir-Blodgett and spin-coating, have been developed to transition synthetic nanowires from disordered to ordered states, but a lack of understanding of assembly mechanisms limits practical applications.
- Advanced in situ techniques like synchrotron-based X-ray and transmission electron microscopy are now enabling dynamic monitoring of nanowire behavior, which is crucial for optimizing assembly structures and linking nanoscale properties to macroscopic functionalities.
Article Synopsis
- Understanding atomic migration in catalysts is key for improving their performance in reactions.
- The study outlines a novel method for converting noble-metal nanoparticles into single atom alloys using thermal treatment with hydrogen and argon.
- Findings show that this conversion results from the combination of hydrogen dissociation and the reduction of metal oxide supports, providing insights into catalyst design and nanomaterial formation.
Fatal community-acquired bloodstream infection caused by : A case report.
World J Clin Cases
March 2022
Article Synopsis
- A 52-year-old male patient showed severe symptoms and was admitted to the hospital, where initial tests ruled out several potential infections but bacterial cultures revealed a highly lethal subspecies of an infective microorganism.
- Despite treatment with carbapenem antibiotics, the patient's condition deteriorated rapidly leading to death just 72 hours after symptom onset due to septic shock.
- This case study highlights the critical need for advanced genetic testing in diagnosing and managing infections, especially those caused by virulent subspecies, to improve patient outcomes.
Article Synopsis
- The study investigates how globalization and increased international travel contribute to the importation of respiratory infectious diseases (RIDs) in China, using data from 2014 to 2018.
- It found that over 31,000 cases of imported RIDs were reported during this period, mostly comprised of influenza, with a notable increase in incidence rates over the years.
- The findings highlight the need for enhanced surveillance and high-tech methods to detect and prevent the spread of imported RIDs to safeguard public health in China.
Article Synopsis
- Sepsis is a serious condition resulting from the body's improper response to infection, with TLR-4 playing a crucial role in inflammation and immune cell death.
- Clinical trials using monoclonal antibodies targeting TLR-4 and immunotherapy focusing on inflammatory cytokines have not been successful in treating sepsis.
- Recent research suggests that the innate immune system is more important for controlling sepsis progression than the adaptive immune system, leading to a proposed shift in treatment strategies and highlighting the potential role of TREML4 in sepsis management.
Article Synopsis
- - SARS-CoV-2 causes a global health crisis due to its high infectivity and rapid spread, leading to severe cases of COVID-19 with complications.
- - Advances in understanding SARS-CoV-2's molecular biology have revealed various laboratory biomarkers that can aid in diagnosing, treating, and predicting patient outcomes for COVID-19.
- - This review highlights the current progress in identifying COVID-19-related biomarkers and suggests future approaches for their application in clinical settings.