Effect of proteins on the oxidase-like activity of CeO nanozymes for immunoassays.

Having the benefits of low cost, excellent stability and tolerance to extreme conditions, nanozymes are a potential alternative of horseradish peroxidase (HRP) or other enzymes for bioanalytical chemistry, especially immunoassays. CeO nanoparticles have oxidase-mimicking activity and can avoid the use of unstable HO. For robust assays, the effect of proteins on the activity of CeO needs to be carefully studied.