Publications by authors named "Jin-Jin Zhao"
Article Synopsis
- * In this study, the quinoline-2-thione derivative KA3D was tested and showed effectiveness in reducing the viability of ovarian cancer cells, causing cell death (apoptosis), and disrupting the cell cycle, specifically blocking the G2 phase.
- * Mechanistic analysis revealed that KA3D promotes the expression of pro-apoptotic proteins while inhibiting anti-apoptotic ones; in animal tests, KA3D effectively suppressed cancer growth without significant side effects, indicating its potential as a chemotherapy agent.
Two isostructural lanthanide complexes were synthesized by solvent evaporation with 3-dimethylaminobenzoic acid and 5,5'-dimethyl-2,2'-bipyridine as ligands. The general formula of the structure is a [Ln(3-N,N-DMBA)(5,5'-DM-2,2'-bipy)]·2(3-N,N-DMHBA), Ln = (Gd(), Tb()), 3-N,N-DMBA = 3-Dimethylamino benzoate, 5,5'-DM-2,2'-bipy = 5,5'-dimethyl-2,2' bipyridine. Both complexes exhibited dimeric structures based on X-ray diffraction analysis.
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- Cistanche is a traditional Chinese medicine known for its dried stems high in phenylethanol glycosides (PhGs), especially in Cistanche tubulosa compared to Cistanche deserticola; however, the genes responsible for PhGs production in C. tubulosa are not fully understood.
- This study utilized advanced sequencing technologies to analyze the full transcriptome of C. tubulosa, resulting in 237,772 unique transcripts and identifying 22 enzymes related to PhGs biosynthesis, with a significant reduction in PhGs content from young stems to harvest stage.
- The research is a pioneering exploration of C. tubulosa's transcriptome, paving the way for further investigation into the biosynthesis of
P-N depleted bulk BiOBr/α-FeO heterojunction (DBH) nanostructures with the growth of (001) BiOBr facets were prepared via a simple hydrothermal method. BiOBr possesses an average thickness of around 50 nm and shows preferential exposure of the (001) facets. α-FeO nanoparticles, with an average diameter of 5 nm, are attached on the surface of BiOBr as 20-50 nm clusters with an intimate contact interface.
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- Lecanicillium lecanii, a biopesticide, was genetically modified using a polyethylene glycol (PEG)-mediated system to enhance its effectiveness against agricultural pests, specifically Aphis gossypii.
- The incorporation of the CDEP1 protease gene from Beauveria bassiana increased the fungal virulence, resulting in a doubled lethality (LC50) rate and faster action against the pests compared to the wild type.
- The study concluded that the PEG-mediated transformation was successful, significantly improving the fungal's ability to combat cotton aphids without adversely affecting its growth and reproduction on a colony level.
Article Synopsis
- The entomopathogenic fungus L. lecanii is used as a biopesticide for insect control in agriculture, but its persistence in soil had not been thoroughly studied until now.
- A selective medium using cetyl trimethyl ammonium bromide (CTAB) was created to isolate and count L. lecanii in soil, providing satisfactory recovery rates.
- The study found that L. lecanii could persist for at least 14 months in agricultural soil, with its population declining quickly initially, stabilizing for several months, and then gradually decreasing until undetectable.
Lecanicillium lecanii has been used in the biological control of several insects in agricultural practice. Since the gene manipulation tools for this entomopathogenic fungus have not been sufficiently developed, Agrobacterium tumefaciens-mediated transformation (ATMT) in L. lecanii was investigated in this study, using the wild-type isolate FZ9906 as a progenitor strain and the hygromycin B resistance (hph) gene as a selection marker.
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- The study investigates a green strategy to enhance the value of biomass by creating hybrids from lignocelluloses and silver using an eco-friendly sonochemistry method with NaBH4 as a reducing agent.
- The characteristics of these hybrids, such as phase, microstructure, and morphology, were analyzed using various techniques including XRD, SEM, TGA, and DTA, while also examining the effects of different reaction parameters.
- These silver-lignocellulose hybrids show potential as antimicrobial materials for biomedical applications, highlighting a sustainable approach to utilizing lignocelluloses.
This study aims to investigate the fabrication and property of cellulose/Ag/AgCl hybrids. In this article, preparation of cellulose/Ag/AgCl hybrids was reported using the cellulose solution, AgNO₃, AlCl₃·6H₂O with ultrasound agitation method. The cellulose solution was synthesized by the dissolution of the microcrystalline cellulose in NaOH/urea aqueous solution.
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