Publications by authors named "Jin-Hun Park"
Article Synopsis
- Current image-based methods for monitoring cell confluency are subjective, leading to inconsistencies in cell therapy quality.
- A deep neural network was used to analyze images of mesenchymal stem cells from different culture vessels, employing a classification and detection algorithm to assess cell status accurately.
- This research is groundbreaking in using deep learning for analyzing cell images, enhancing the yield and quality critical to stem cell therapeutics.
Background: Musculoskeletal symptoms, such as neck pain and low back pain (LBP) are common after a traffic accident (TA). While motion-style acupuncture treatment (MSAT) is effective in relieving pain, MSAT using traction (T-MSAT) has rarely been studied, and evidence for its efficacy and safety is lacking. To address this gap, this study aimed to assess the effectiveness and safety of T-MSAT for pain and functional disturbances in patients with acute LBP caused by a TA.
View Article and Find Full Text PDFAims: The association between skeletal muscle mass and diabetes incidence/insulin resistance/glycated hemoglobin (HbA1C) is unknown. The aim of this study was to investigate such association in clinically apparently healthy males and females.
Methods: A cross-sectional study of 372,399 Korean males and females who completed bioelectrical impedance analysis (BIA) in a health-screening programme was performed.
Article Synopsis
- The study investigates the link between posterior delamination of the rotator cuff and subscapularis tendon tears, noting a lack of previous research on this relationship.
- Conducted from March 2018 to June 2021 with 553 patients, the research compares various factors like age, tear size, symptom duration, and shoulder function between groups with delaminated and nondelaminated rotator cuff tears.
- Results show that older patients with larger tears are more likely to have delamination; those with delamination also experience longer symptoms, worse shoulder function, and a higher prevalence of subscapularis tears compared to those without delamination.
Background: The association of the severity of clinical symptoms and level of functional performance with the degree of magnetic resonance imaging abnormalities in patients with lateral epicondylitis has not been fully elucidated. This study aimed to investigate the association between the degree of anatomical abnormalities by evaluating three-dimensional magnetic resonance imaging models of the common extensor tendon and clinical parameters in patients with lateral epicondylitis.
Materials And Methods: A total of 61 patients (24 men and 37 women) with lateral epicondylitis were included in this study.
Background: The number of patients with an osteoporotic vertebral compression fracture, which is often accompanied by lower back pain and restrained activities, is growing. Balloon kyphoplasty involves the inflation of a balloon to restore height and reduce kyphotic deformity before stabilization with polymethylmethacrylate. However, there is a great deal of debate about whether balloon kyphoplasty also increases fracture morbidity by either inducing or facilitating subsequent adjacent vertebral fractures.
View Article and Find Full Text PDFArticle Synopsis
- - The study focuses on treating acute low back pain (LBP) caused by traffic accidents using a specific acupuncture therapy called motion style acupuncture therapy with traction (T-MSAT).
- - Conducted at Jaseng Hospital in South Korea, the randomized controlled trial (RCT) will involve 100 participants, comparing T-MSAT combined with integrative Korean medicine therapy against a control group receiving only the latter.
- - The outcomes will analyze pain relief and functional improvements using various scales, and the results can inform policymakers and healthcare providers on effective treatments for LBP post-traffic accidents.
Article Synopsis
- The article was initially published on August 5, 2020.
- There was an error present in the original version.
- The article likely underwent a revision to correct this mistake.
Article Synopsis
- The study compared bone mineral density (BMD) between two groups of proximal hip fractures: femoral neck fractures and intertrochanteric fractures, using data from 329 patients collected from 2010 to 2017.
- The results showed that BMD was significantly lower in the intertrochanteric fracture group, with beta values being approximately twice as high compared to the femoral neck fracture group.
- These findings highlight the importance of recognizing differences in fracture types to enhance treatment strategies and outcomes for patients.
Article Synopsis
- * 50 patients who had one-level corpectomy or discectomies were analyzed, with two types of plates used: Codman and Zephir, and dysphagia was assessed through follow-up interviews.
- * Results showed that dysphagia rates (20% short-term, 14% persistent) were similar regardless of the plate type, indicating plate size does not influence the risk of developing dysphagia post-surgery.
Study Design: A retrospective study.
Objective: To analyze the clinical outcomes and radiologic changes after microsurgical bilateral decompression via a unilateral approach in patients with lumbar spinal stenosis (LSS) and degenerative spondylolisthesis (DS).
Summary Of Background Data: Satisfactory short-term results have been observed after minimally invasive decompressive procedures, but intermediate-term and long-term outcomes have not been assessed.
A series of 18 new imidazo[2,1-b]thiazole derivatives was synthesized. Their in vitro antiproliferative activities against A375P human melanoma cell line and NCI-60 cell line panel were tested. Compounds 15, 16, 18, 22, 26-28, and 31 showed superior potency against A375P to sorafenib.
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- A study was conducted on new amides and esters prodrugs of olmesartan to assess their effectiveness.
- The ester derivative IIa was found to quickly convert into olmesartan in rat plasma, doing so within just 30 minutes.
- Pharmacokinetic analysis suggests that IIa could serve as a promising prodrug for olmesartan, potentially improving its therapeutic use.
Synthesis of a new series of diarylureas and amides having pyrrolo[2,3-d]pyrimidine scaffold is described. Their in vitro antiproliferative activities against A375 human melanoma cell line and HS 27 fibroblast cell line were tested and the effect of substituents on pyrrolo[2,3-d]pyrimidine was investigated. The newly synthesized compounds, except N-acetyl derivatives (Id, Ie, and Im), generally showed superior or similar activity against A375 to Sorafenib.
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