Publications by authors named "Jin-Hui Su"

Article Synopsis
  • Probiotic pretreatment using Lactobacillus johnsonii L531 is effective in preventing Salmonella infections in piglets, reducing diarrhea and inflammation when administered before infection.
  • Treatment with L. johnsonii increases the abundance of beneficial bacteria in the ileum, decreases total bacteria in the ileal mucosa, and reduces tissue damage due to Salmonella.
  • The study shows that L. johnsonii L531 positively influences T-cell responses and alleviates endoplasmic reticulum stress, contributing to intestinal health during bacterial challenges.
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  • Intestinal pathogenic E. coli (InPEC) is a major cause of postweaning diarrhea (PWD) in pigs, with a study isolating 455 strains from affected pigs on large-scale farms between 2014 and 2016.
  • Real-time PCR revealed that the most common virulence factor was the heat-labile enterotoxin (LT), followed by other toxins like heat-stable enterotoxin (STb), with significant variation based on location and year.
  • A concerning finding was that 94.15% of the isolates were multidrug-resistant, highlighting the need for better strategies to combat InPEC-related diarrheal diseases in pigs.
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  • - The study evaluates the impact of a mixture called LBB-mix, consisting of L531, BL1721, and BS1715, on preventing Serovar Infantis infection in piglets, which is significant for both swine health and potential human food-borne illness transmission.
  • - Administering LBB-mix to newly weaned piglets before exposure to the infection resulted in reduced fever, immune response, growth issues, and inflammation in the intestines, while also decreasing harmful bacteria in their feces.
  • - The treatment with LBB-mix helped maintain the integrity of the intestinal barrier and reduced cell death caused by the infection, indicating its potential as a protective measure against Serovar Infantis in pigs.
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In the current study, we screened Lactobacillus strains isolated from the colon of clinically healthy weaned piglets for potential probiotic properties and isolated Lactobacillus. johnsonii L531, which produced high levels of beneficial metabolites (butyric, acetic, and lactic acid) in vitro. We also evaluated the efficacy of this metabolites-producing probiotic in treating Salmonella.

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Article Synopsis
  • The study explored the frequency and distribution of bacterial serovars and antimicrobial resistance in pig isolates with diarrhea across 26 provinces in China from 2014 to 2016.
  • A total of 104 isolates were identified, with 4,[5],12:i:- being the most common serovar, and all isolates showed resistance to trimethoprim-sulfamethoxazole and high levels of resistance to other antibiotics like ampicillin and tetracycline.
  • Genetic analysis revealed that while the isolates were diverse, clonal expansion occurred with ST34 being the most prevalent, indicating a widespread problem of multidrug-resistant bacteria in pigs that may impact farming practices.
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The Yangtze River Basin in China is one of the global hotspots of freshwater mussel (order Unionida) diversity with 68 nominal species. Few studies have tested the validity of these nominal species. Some taxa from the Yangtze unionid fauna have not been adequately examined using molecular data and well-positioned phylogenetically with respect to the global Unionida.

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serovar Infantis (. Infantis) is a common source of foodborne gastroenteritis worldwide. Here, GG (LGG) was administrated to weaned piglets for 1 week before .

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The family Margaritiferidae encompasses 12 valid species, which are distributed widely but disjunctively in the Northern Hemisphere. A lack of a well resolved and temporally calibrated phylogenetic framework of Margaritiferidae has made it difficult to discuss the evolutionary pattern and process. Phylogenetic relationships between five major clades, which were revealed in earlier studies, remain elusive and unresolved.

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In this study, we investigated the effect of Lactobacillus rhamnosus GG strain (LGG) in ameliorating enteritis in newly weaned pigs following challenge with a monophasic variant of Salmonella enterica serovar Typhimurium (serotyped as 4,[5],12:i:-), which has been linked to disease in humans and livestocks over the past 10 years. In weaned pigs, S. enterica serovar 4,[5],12:i:- induced the mRNA expression of toll like receptor (TLR) 5 and TLR4, while increasing interleukin (IL)-8 and IL-6 mRNA expression in the jejunum.

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The high rate of serovar Infantis (. Infantis) infection poses significant risk for the development of non-typhoidal gastroenteritis. However, efficient strategies to prevent or treat the infection remain elusive.

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A traditional capsule endoscope can only take 2D images, and most of the images are not clear enough to be used for diagnosing. A 3D capsule endoscope can help doctors make a quicker and more accurate diagnosis. However, blurred images negatively affect reconstruction accuracy.

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Objective: The study aims to evaluate the effectiveness of voice therapy (VT) and analyze the vocal aerodynamic characteristics in mutational falsetto (MF) patients.

Methods: From October 2010 through May 2014, 26 patients with MF at Sun Yat-sen Memorial Hospital were studied retrospectively. Vocal assessment, including the 10-item Voice Handicap Index (VHI-10), fundamental frequency (F0), and vocal aerodynamic parameters (subglottic pressure [SGP]), aerodynamic power [AP], mean expiratory airflow, and maximum phonation time [MPT]), was proceeded before and after VT.

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