Publications by authors named "Jin-Hao Yu"
Circular RNAs (circRNAs) are a distinct class of non-coding RNAs that play regulatory roles in the initiation and progression of tumors. With advancements in transcriptome sequencing technology, numerous circRNAs that play significant roles in tumor-related genes have been identified. In this study, we used transcriptome sequencing to analyze the expression levels of circRNAs in normal adjacent tissues, primary colorectal cancer (CRC) tissues, and CRC tissues with liver metastasis.
View Article and Find Full Text PDFMany studies reported that long noncoding RNAs (lncRNAs) play a critical role in gastric cancer (GC) metastasis and tumorigenesis. However, the underlying mechanisms of lncRNAs in GC remain unexplored to a great extent. LINC01537 expression level was detected using quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and immunohistochemistry (IHC).
View Article and Find Full Text PDF[Genetic algorithm-based dose optimization in intensity modulated radiation therapy].
Nan Fang Yi Ke Da Xue Xue Bao
January 2007
Article Synopsis
- Genetic algorithms (GA) are effective for optimizing complex problems that might be discontinuous or highly non-linear, offering quick convergence and extensive search capabilities.
- This thesis applies GA specifically to optimize beam weights in intensity modulated radiation therapy (IMRT) inverse planning, which is crucial for improving cancer treatment.
- The research includes evaluations of treatment plans using 2D and 3D isodose contours and dose volume histograms (DVH), along with discussions of the results achieved.
[A new method for static intensity-modulated radiation therapy].
Di Yi Jun Yi Da Xue Xue Bao
December 2005
Objective: To develop a new method for static intensity-modulated radiation therapy (IMRT) possible for implementation in smaller hospitals by incorporating accurate location equipments and treatment planning system in the available equipments for general radiotherapy.
Methods: Based on the techniques of conformal radiotherapy, a new split method for fabricating the three-dimensional physical compensator was developed to achieve IMRT.
Results: Experiment with the new method showed that the fabricated compensator could achieve good match between the high dosage shape in the target area and the dimensions of the tumor, and allowed adjustment of the dosage distribution according to the therapeutic requirement.