Publications by authors named "Jin-Chun Wu"
Ferroptosis is a novel, iron-dependent cell death characterized by the excessive accumulation of ferroptosis lipid peroxides ultimately leading to oxidative damage to the cell membrane. Iron, lipid, amino acid metabolism, and other signaling pathways all control ferroptosis. Numerous bodily tissues experience hypoxia under normal and pathological circumstances.
View Article and Find Full Text PDFBackground: Regulatory T (Treg) cells are a class of anti-inflammatory lymphocyte subpopulations with a potential protective effect against atherosclerosis, whereas T helper 17 (Th17) cells have been reported to possess proatherogenic activity. It was believed that disturbed circulating Treg/Th17 balance was associated with the onset and progression of atherosclerosis. This study is designed to probe the regulative action of serum Nod-like receptor protein 3 (NLRP3) on the Treg/Th17 balance in patients with atherosclerosis.
View Article and Find Full Text PDFArticle Synopsis
- A study aimed to evaluate the learning curve of robotic portal lobectomy with four arms (RPL-4) in patients with lung tumors using data collected prospectively from 100 consecutive cases.
- The analysis identified three distinct phases in the learning curve: an initial learning phase (1-10 cases), a plateau phase (11-51 cases), and a mastery phase (beyond 51 cases), with a mastery expertise requiring at least 56 cases for optimal surgical outcomes.
- As surgeons gained experience, they showed significant reductions in operative time, console time, and docking time, indicating improved efficiency over time, though not all clinical indicators varied across the phases.
[The correlation analysis between glucose level and its variability and prognosis in traumatic patients].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
November 2012
Objective: To investigate the effect of glucose level, variability on the prognosis of traumatic patients.
Methods: A retrospective study involving 300 traumatic patients admitted to intensive care unit (ICU) was performed. The average glucose (GluAve), glucose standard deviation (GluSD) and glucose coefficient of variation (GluCV) during the first 72 hours were calculated.