Publications by authors named "Jin Yue Liu"
Background: Haemaphysalis concinna, carrying multiple pathogens, has attracted increasing attention because of its expanded geographical range and significant role in disease transmission. This study aimed to identify the potential public health risks posed by H. concinna and H.
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- Malaria cases in Niger skyrocketed from over 592,000 in 2000 to over 3 million in 2010, prompting a major public health response with various interventions, although their effectiveness requires further examination.
- A study conducted from 2010 to 2019 analyzed malaria data, revealing a decrease in incidence rates regionally, but with an increase in mortality and case fatality ratios in certain age groups, especially among 10-24 year olds.
- While some malaria interventions effectively reduced incidence rates, challenges persist in controlling mortality rates, indicating a need for improved surveillance, diagnosis, treatment, and preventive measures like insecticide-treated bed nets in Niger.
There has been increasing global concern about the spillover transmission of pangolin-associated microbes. To assess the risk of these microbes for emergence as human pathogens, we integrated data from multiple sources to describe the distribution and spectrum of microbes harbored by pangolins. Wild and trafficked pangolins have been mainly recorded in Asia and Africa, while captive pangolins have been reported in European and North American countries.
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- * The systematic review created a detailed database capturing the pathogen's distribution, prevalence, and genetic diversity through phylogenetic analyses, with A. capra found in 18 countries across Asia, Europe, and Africa.
- * The research indicated that domestic ruminants, especially goats and sheep, are primary hosts, with certain ticks like Haemaphysalis longicornis being key carriers, while habitat modeling identified optimal regions for A. capra mainly in Asia and eastern Europe.
The seasonal human coronaviruses (HCoVs) have zoonotic origins, repeated infections, and global transmission. The objectives of this study are to elaborate the epidemiological and evolutionary characteristics of HCoVs from patients with acute respiratory illness. We conducted a multicenter surveillance at 36 sentinel hospitals of Beijing Metropolis, China, during 2016-2019.
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- A tick-borne protozoan poses a significant veterinary health threat to livestock and wildlife, with a limited number of genome sequences available until now.
- Researchers at Cheeloo College of Medicine sequenced the whole genome of a new strain, named str. Cheeloo, derived from infected goats, revealing it has the smallest genome size and fewer gene variations compared to other known species.
- The findings indicate a high infection rate (81.5%) in goats, highlighting str. Cheeloo's significance in the understanding and control of theileriosis, which has resulted in considerable economic losses in animal husbandry.
The increasing incidence and range expansion of tick-borne diseases have caused global threats to human and animal health under the background of climate and socioeconomic changes. As an efficient vector in transmission of tick-borne diseases, a growing burden caused by and associated pathogens could not be underestimated. This study summarized the distribution, hosts, and pathogens of , and predicted the suitable habitats of this tick species worldwide.
View Article and Find Full Text PDFThe increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses.
View Article and Find Full Text PDFTrigeminal ganglion (TG) is the first station of sensory pathways in the orofacial region. The TG neurons communicate with satellite glial cells (SGCs), macrophages and other cells forming a functional unit that is responsible for processing of orofacial sensory information. Purinergic signaling, one of the most widespread autocrine and paracrine pathways, plays a crucial role in intercellular communication.
View Article and Find Full Text PDFObjectives: To investigate the independent and collective impact of alcohol drinking and tobacco smoking on the drug-resistance of newly diagnosed tuberculosis (TB).
Design: This was a retrospective cohort study.
Setting: Shandong, China.
Article Synopsis
- Respiratory syncytial virus (RSV) is an RNA virus that primarily causes severe respiratory illness in children under two, as well as affecting infants and the elderly globally.
- RSV circulates only among humans but was first isolated from chimpanzees; while it can infect some lab animals, it doesn’t naturally spread in them.
- Research discovered that Malayan pangolins have RSV strains closely related to human strains, indicating the possibility of human-to-wildlife transmission of the virus.
Background: The current surveillance system only focuses on notifiable infectious diseases in China. The arrival of the big-data era provides us a chance to elaborate on the full spectrum of infectious diseases.
Methods: In this population-based observational study, we used multiple health-related data extracted from the Shandong Multi-Center Healthcare Big Data Platform from January 2013 to June 2017 to estimate the incidence density and describe the epidemiological characteristics and dynamics of various infectious diseases in a population of 3,987,573 individuals in Shandong province, China.
Background: Drug-resistant tuberculosis (DR-TB), obesity, and malnutrition are growing public health problems in the world. However, little has discussed the impact of different BMI status on the emergence of TB drug resistance. We aimed to explore the drug-resistant profiles of DR-TB and its clinical predictors among underweight, overweight or obesity population.
View Article and Find Full Text PDFCoronavirus disease 2019 (COVID-19) and tuberculosis (TB) are two major infectious diseases posing significant public health threats, and their coinfection (aptly abbreviated COVID-TB) makes the situation worse. This study aimed to investigate the clinical features and prognosis of COVID-TB cases. The PubMed, Embase, Cochrane, CNKI, and Wanfang databases were searched for relevant studies published through December 18, 2020.
View Article and Find Full Text PDFDrug-Resistant Tuberculosis Among Children: A Systematic Review and Meta-Analysis.
Front Public Health
October 2021
Drug-resistant tuberculosis (DR-TB), especially multidrug-resistant tuberculosis (MDR-TB) is a public health threat. Little is known about estimates of different profiles and rates of DR-TB among children globally. We did a systematic review and meta-analysis of observational studies reporting DR-TB among children by searching Embase, PubMed, and Scopus databases from January 1, 2000 to October 1, 2020.
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- The study aimed to identify risk factors for drug-resistant tuberculosis (DR-TB) and how comorbid conditions affect drug resistance in patients being retreated for pulmonary tuberculosis (PTB) in Shandong, China, over a 16-year period.
- Out of nearly 11,000 PTB patients, 26.2% were found to have DR-TB, with smoking, lung cavities, and comorbidities like diabetes and hypertension identified as significant risk factors for developing drug resistance during treatment.
- Comorbidities were associated with higher rates of various drug resistances, and patients with these conditions were generally older and had poorer lifestyle habits, emphasizing the need for targeted interventions in vulnerable populations.
Ambient air pollutants, diabetes and risk of newly diagnosed drug-resistant tuberculosis.
Ecotoxicol Environ Saf
August 2021
Background: Drug-resistant tuberculosis (DR-TB), diabetes and exposure to air pollution are thought to be important threat to human health, but no studies have explored the effects of ambient air pollutants on DR-TB when adjusting diabetes status so far.
Methods: We performed a study among 3759 newly diagnosed TB cases with drug-susceptibility testing results, diabetes status, and individual air pollution data in Shandong from 2015 to 2019. Generalized linear mixed models (GLMM) including three models (Model 1: without covariates, Model 2: adjusted by diabetes status only, Model 3: with all covariates) were applied.
Background: Considering the high morbidity and mortality of lung cancer and the high incidence of pulmonary nodules, clearly distinguishing benign from malignant lung nodules at an early stage is of great significance. However, determining the kind of lung nodule which is more prone to lung cancer remains a problem worldwide.
Methods: A total of 480 patients with pulmonary nodule data were collected from Shandong, China.
Background: To explore population aging and the epidemic trend of pulmonary tuberculosis (PTB) in the elderly, and provide a basis for the prevention and control of pulmonary tuberculosis among the elderly.
Methods: We collected clinical information of 239,707 newly active PTB patients in Shandong Province from 2005 to 2017. We analyzed and compared the clinical characteristics, reported incidence and temporal trend of PTB among the elderly group (≥60 years) and the non-elderly group (< 60 years) through logistic model and Join-point regression model.
The releasing of transgenic soybeans (Glycine max (L.) Merr.) into farming systems raises concerns that transgenes might escape from the soybeans via pollen into their endemic wild relatives, the wild soybean (Glycine soja Sieb.
View Article and Find Full Text PDFBackground: Tuberculosis (TB) is one of the major infectious diseases that seriously endanger people's health. In Shandong province, the relationship between the level of economic development and TB incidence has not been studied. This study aims to provide more research basis for the government to prevent and control TB by exploring the impact of different economic factors on TB incidence.
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- * Results show that TB patients with diabetes exhibit a higher rate of drug resistance (34.41% vs. 25.00% for non-DM patients) and have significantly increased odds of various drug-resistant TB profiles.
- * These findings highlight the importance of monitoring drug resistance in TB patients with diabetes due to their elevated risk, emphasizing a need for targeted interventions.
Background: Primary drug-resistant tuberculosis (DR-TB) has contributed to a significant health and economic burden on a global scale, especially in China. we sought to estimate epidemiological characteristics of primary DR-TB in China from 2004 to 2018.
Methods: Eleven thousand four hundred sixty-seven newly diagnosed and 1981 retreated TB cases with drug susceptibility data were included.
Article Synopsis
- The study explored the relationship between tuberculosis (TB) and diabetes mellitus (DM) in China, highlighting the increased risk of drug-resistant tuberculosis (DR-TB) in TB patients who also have diabetes from 2004 to 2017. !* -
- Among 7,223 newly diagnosed TB patients, 5.90% were identified as TB-DM cases, which showed higher rates of drug resistance compared to TB patients without diabetes, particularly in forms like polydrug resistant TB (PDR-TB) and streptomycin-resistant TB. !* -
- The findings conclude that diabetes significantly contributes to a higher likelihood of drug resistance in TB patients, emphasizing the need for improved management of diabetes to aid