Synergistic effects of rare earth doping and carbon quantum dots on BiOF/BiMoO heterojunctions for enhanced visible-near-infrared photocatalysis.

Herein, we designed and synthesized a series of rare earth doped BiOF/BiMoO heterojunctions. The doping locations of rare earth ions were altered to determine the influence on the visible and near-infrared photocatalytic activity of heterojunctions. It is experimentally and theoretically confirmed that doping with Tm/Yb in one semiconductor of the heterojunction produces superior photocatalytic efficiency than doping in both semiconductors.

Long noncoding RNA ADAMTS9-AS1 represses ferroptosis of endometrial stromal cells by regulating the miR-6516-5p/GPX4 axis in endometriosis.

Endometriosis (EMs) is one of the most frequent diseases of reproductive-age women and is characterized by the growth of endometrial tissues beyond the uterus. The enhanced proliferative and migratory potential of endometrial stromal cells (ESCs) plays an important role in the progression of EMs. Mounting studies have demonstrated that long noncoding RNAs (lncRNAs) exert an important role in regulating the development and progression of EMs.

The periumbilical incision for anterior lumbar interbody fusions.

The traditional retroperitoneal approach for the anterior lumbar interbody fusion (ALIF) uses a longitudinal paramedian incision. In this study, we use a discrete periumbilical incision. A 270-degree semicircular incision is made around the umbilicus and the subcutaneous tissue is dissected radially at a 45-degree angle, creating a mound around the umbilical stalk.

Lung transplant patients with coronary artery disease rarely die of cardiac causes.

Background: A relative contraindication for lung transplant (LT) is coronary disease burden sufficient to cause risk of myocardial infarction after LT. We analyzed cause of death and outcomes of our LT patients with coronary artery disease (CAD).

Methods: Inpatient records from March 1, 2004, to January 31, 2015, were retrospectively examined and data of 306 LTs extracted.

[Design of sponge city and its inspiration to landscape ecology: A case of Liaodong Bay area of Panjin City, Northeast China].

With the expansion of urban area, many cities are facing urban water environment issues, i.e., water resources shortage, lack of groundwater reserves, water pollution, urban waterlogging.

[Non-point source pollution simulation under land use change scenarios in Hun-Taizi River watershed.].

Non-point source (NPS) pollution has become a major source of water pollution in recent years. The research of NPS pollution mechanism and control has an important scientific and practical meaning. To study the effect of land use change on NPS pollution load, near future land use of Hun-Taizi River watershed was simulated under three scenarios based on CLUE-S model, including urban planning, historical trend and ecological protection scenarios.

A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P(2).

Inwardly rectifying potassium (Kir) channels are gated by the membrane phospholipid phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P(2)). Among them, Kir3 requires additional molecules, such as the betagamma subunits of G proteins or intracellular sodium, for channel gating. Using an interactive computational-experimental approach, we show that sodium sensitivity of Kir channels involves the side chains of an aspartate and a histidine located across from each other in a crucial loop in the cytosolic domain, as well as the backbone carbonyls of two more residues and a water molecule.

Stoichiometry of Kir channels with phosphatidylinositol bisphosphate.

Phosphatidylinositol bisphosphate (PIP(2)) is the most abundant phosphoinositide in the plasma membrane of cells and its interaction with many ion channel proteins has proven to be a critical factor enabling ion channel gating. All members of the inwardly rectifying potassium (Kir) channel family depend on PIP(2) for their activity, displaying distinct affinities and stereospecificities of interaction with the phosphoinositide. Here, we explored the stoichiometry of Kir channels with PIP(2).

Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K+ channels.

Neurotransmitter and hormone regulation of cellular function can result from a concomitant stimulation of different signaling pathways. Signaling cascades are strongly regulated during disease and are often targeted by commonly used drugs. Crosstalk of different signaling pathways can have profound effects on the regulation of cell excitability.

Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

Kir3.4 and Kir3.1 potassium channel subunits mediate the acetylcholine induced inwardly rectifying current I(KACh) in the heart.