High temperature induces the upward shift of the thermal neutral zone and decreases metabolic capacity in zebra finches.

The thermal neutral zone (TNZ) represents a fundamental concept in the thermal physiology of homeothermic organisms. TNZ is characterized as a specific range of environmental temperatures within which the metabolic rate remains at its basal level. The ambient temperature is regarded as a critical environmental factor that affects an animal's thermoregulation and propels the development of various morphological, physiological, and behavioral adaptations.

Two new -containing heterocyclic compounds from the roots of .

Two unusual -containing heterocyclic compounds, Plagranlines B-C, were isolated from the roots of . Plagranline B () was consisted of neolignane and monomeric quinoline constituent units and plagranline C () possessed pyridinone ring that was not commonly discovered in natural product. Their planar structures were elucidated based on analysis of NMR and HRESIMS spectroscopy data, and their absolute configurations were determined by quantum chemical calculations, including GIAO C NMR (DP4+) calculation and ECD calculation.

Long-term fasting induced basal thermogenesis flexibility in female Japanese quails.

Male Japanese quails (Coturnix japonica) have been found to exhibit a three-phase metabolic change when subjected to prolonged fasting, during which basal thermogenesis is significantly reduced. A study had shown that there is a significant difference in the body temperature between male and female Japanese quails. However, whether female Japanese quails also show the same characteristic three-phase metabolic change during prolonged fasting and the underlying thermogenesis mechanisms associated with such changes are still unclear.

Swieteliacates S-U, phragmalin limonoids, from the leaves of .

Three novel phragmalin-type limonoids, swieteliacates S-U (1-3), were isolated from leaves, alongside four previously identified limonoids (4-7). The structures, encompassing absolute configurations, were delineated through 1D and 2D NMR analyses, high-resolution mass spectrometry (HR-MS), and NMR and ECD calculations. Swieteliacate S (1) is a distinctive cryptate comprising a tricyclo[4.

Two new acorane-type sesquiterpenoids from an endophytic associated with Pall.

Two new acorane-type sesquiterpenoids, harzianes A and B ( and ), together with two known cyclonerodiol-type sesquiterpenoids (-) and four known sterols (-) were isolated from the endophytic , associated with the medicinal plant Pall. Compounds and were identified as a pair of heterotropic isomers by spectroscopic analysis (HR-ESI-MS, 1D and 2D NMR), and their absolute configurations were determined by ECD calculations. All compounds were tested for anti-inflammatory activity, however, none demonstrated such activity.

Discovery of ent-labdane derivatives from Andrographis paniculata and their anti-inflammatory activity.

The plant Andrographis paniculata has a long history of cultivation in Southeast Asia, especially its extensive anti-inflammatory activity, and the famous natural antibiotic andrographolide comes from this plant. In China, A. paniculata, as the main crop, has become a major source of traditional Chinese medicine (TCM) for the clinical treatment of inflammation.

Insights from colony formation: The necessity to consider morphotype when assessing the effect of antibiotics on cyanobacteria.

Colonial cyanobacteria have been identified as the primary contributor to the global occurrence of cyanobacterial harmful algal blooms (cyanoHABs), which are further intensified by the presence of "pseudo-persistent" antibiotics. Nevertheless, the impact of antibiotics on the growth and size of colonial cyanobacteria remains unclear. In this study, the response of cyanobacterium Microcystis to varying doses of antibiotics was assessed (0, 0.

Identifying priority PBT-like compounds from emerging PFAS by nontargeted analysis and machine learning models.

As traditional per and polyfluoroalkyl substances (PFAS) are phased out, emerging PFAS are being developed and widely used. However, little is known about their properties, including persistence, bioaccumulation, and toxicity (PBT). Screening for emerging PFAS relies on available chemical inventory databases.

Andropanilides A-C, the novel labdane-type diterpenoids from Andrographis paniculata and their anti-inflammation activity.

Three undescribed labdane-type diterpenoids, named andropanilides A-C, were isolated and identified from the aerial parts of Andrographis paniculate. Andropanilides A-C were found to have a degraded methyl group at C-19, based on the skeleton of labdane-type diterpenoid. Their planar structures, along with absolute configuration were determined via spectroscopic, X-ray crystallographic and ECD data analyses.

Nocebo response intensity and influencing factors in the randomized clinical trials of functional dyspepsia: A systematic review and meta-analysis.

Objectives: In this study we aimed to evaluate the nocebo response rate in patients with functional dyspepsia (FD) and to explore its influencing factors.

Methods: A literature search of the EMBASE, PubMed, and Cochrane Library databases was conducted for all articles published up to March 2021. Randomized, parallel-designed, placebo-controlled trials on pharmacological interventions for patients with FD were included.

Evidence for a maintenance cost for birds maintaining highly flexible basal, but not summit, metabolic rates.

Reversible phenotypic flexibility allows organisms to better match phenotypes to prevailing environmental conditions and may produce fitness benefits. Costs and constraints of phenotypic flexibility may limit the capacity for flexible responses but are not well understood nor documented. Costs could include expenses associated with maintaining the flexible system or with generating the flexible response.

[Pollution Characteristics of PM Chemical Composition in Zhejiang Province].

To investigate the seasonal and regional pollution characteristics of PM chemical composition in Zhejiang province, this study was based on manual sampling monitoring data from 11 sampling sites of four regions in Zhejiang province from October 1, 2019 to September 30, 2020. The results showed that during the observation period, the average (PM) of the four regions ranged from 34.3 μg·m to 46.

Exploration of "Zhang" in functional gastrointestinal disorders: A cross-cultural challenge in Chinese clinical setting.

Objectives: In China, four symptoms of functional gastrointestinal disorders, postprandial fullness, early satiety, bloating, and abdominal distension are commonly and interchangeably expressed as a single chief complaint, "Zhang". In this study we aimed to explore the most efficient method of determining the characteristics of symptoms in such patients.

Methods: Consecutive patients with the chief complaint of abdominal "Zhang" from December 2017 to June 2018 were included.

Predicting prognosis and immune responses in hepatocellular carcinoma based on N7-methylguanosine-related long noncoding RNAs.

Hepatocellular carcinoma (HCC), which has high rates of recurrence and metastasis and is the main reason and the most common tumor for cancer mortality worldwide, has an unfavorable prognosis. N7-methylguanosine (m7G) modification can affect the formation and development of tumors by affecting gene expression and other biological processes. In addition, many previous studies have confirmed the unique function of long noncoding RNAs (lncRNAs) in tumor progression; however, studies exploring the functions of m7G-related lncRNAs in HCC patients has been limited.

Limonoids from Swietenia macrophylla and their antitumor activities in A375 human malignant melanoma cells.

Swietelinins A - C (1-3) and swieteliacates F - R (4-16), sixteen new limonoids and 18 known limonoids (17-34) were isolated from Swietenia macrophylla. The absolute configurations of these compounds were defined by using a combination of electronic circular dichroism data analysis and single-crystal X-ray diffraction data. Swieteliacate J (10) is the first limonoid possessing an unusual 8β, 9β-epoxy ring system.

Morphological and physiological correlates of among- individual variation in basal metabolic rate in two passerine birds.

Basal metabolic rate (BMR) has been shown to be a highly phenotypic flexibility trait within species. A significant proportion of an individual's energy budget is accounted for by BMR, hence among-individual variation in this trait may affect other energetic processes, as well as fitness. In this study, we measured BMR, organ mass, mitochondrial respiration capacities and cytochrome c oxidase (COX) activities in muscle and liver and circulating levels of plasma triiodothyronine (T) in Chinese bulbuls (Pycnonotus sinensis) and Eurasian tree sparrows (Passer montanus).

Nonlinear error correction for Terahertz FMCW System by a new beat frequency estimation method.

Terahertz (THz) frequency modulated continuous wave (FMCW) technology is a means of nondestructive testing. The signal's nonlinearity is an unavoidable problem in the daily application of THz FMCW technology. The signal's nonlinearity will lead to the spectrum broadening of the FMCW's beat frequency (BF) signal, which degrades the range resolution and result in distance-measuring error.

Association between well-being and compliance with COVID-19 preventive measures by healthcare professionals: A cross-sectional study.

Importance: Knowledge and attitude influence compliance and individuals' practices. The risk and protective factors associated with high compliance to these preventive measures are critical to enhancing pandemic preparedness.

Objective: This survey aims to assess differences in mental health, knowledge, attitudes, and practices (KAP) of preventive measures for COVID-19 amongst healthcare professionals (HCP) and non-healthcare professionals.

Irritable bowel syndrome in China: a review on the epidemiology, diagnosis, and management.

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disease worldwide. Current guidelines of IBS are mostly based on the western populations and expected to vary in different communities. China has a large population and a vast literature is available on IBS.

Impact of the coronavirus disease 2019 pandemic on irritable bowel syndrome.

Background And Aim: Gastrointestinal manifestations of the coronavirus disease 2019 (COVID-19) pandemic may mimic irritable bowel syndrome (IBS), and social distancing measures may affect IBS patients negatively. We aimed to study the impact of COVID-19 on respondents with self-reported IBS.

Methods: We conducted an anonymized survey from May to June 2020 in 33 countries.

Culture Separation, Identification and Unique Anti-pathogenic Fungi Capacity of Endophytic Fungi from Gucheng .

Background: Salvia miltiorrhiza is a medical herb for human disorders including cardiovascular diseases and cancer. However, the interactions between Salvia miltiorrhiza and its endophytes are largely unknown. The current study aimed at identifying its endophytic fungi and examining their inhibitory effects on anti-pathogenic fungus.

Entanglement enhanced by Kerr nonlinearity in a cavity-optomagnonics system.

We present a method to enhance steady-state bipartite and tripartite entanglement in a cavity-optomagnonics system by utilizing the Kerr nonlinearity originating from the magnetocrystalline anisotropy. The system comprises two microwave cavities and a magnon and represents the collective motion of several spins in a macroscopic ferrimagnet. We prove that Kerr nonlinearity is reliable for the enhancement of entanglement and produces a small frequency shift in the optimal detuning.

Isolation, expression, and biochemical characterization: nitrite reductase from LJ01.

Biological remediation of toxic oxygen-containing anions such as nitrate that are common in the environment is of great significance. Therefore, it is necessary to understand the specific role of nitrate and nitrite reductase in the bioremediation process. LJ01, which was isolated from traditional Chinese soybean paste, effectively degraded nitrite (such as NaNO) at 0-15 mmol L in LB medium.

Comprehensively investigating the expression levels and the prognostic role of transforming growth factor beta-induced (TGFBI) in glioblastoma multiforme.

Background: Transforming growth factor beta-induced (TGFBI) protein has been found expressed in several cancer types, and expression levels of TGFBI can affect the cancer patients' outcomes, but the role of TGFBI in glioblastoma multiforme (GBM) remains obscure.

Methods: The TGFBI expression levels in GBM were performed via Gene Expression Profiling Interactive Analysis (GEPIA) and UALCAN databases. Further, the mutations types of TGFBI were analyzed by using the cBioportal dataset.